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01.12.2017 | Case Report | Ausgabe 1/2017 Open Access

World Journal of Surgical Oncology 1/2017

Postoperative extracranial metastasis from glioblastoma: a case report and review of the literature

World Journal of Surgical Oncology > Ausgabe 1/2017
Wenjiao Wu, Dequan Zhong, Zhan Zhao, Wentao Wang, Jun Li, Wei Zhang



Glioblastoma is the most common primary malignant brain tumor. Extraneural metastases are rarely reported in the literature.

Case presentation

We report a case of a 38-year-old patient who was diagnosed with glioblastoma in 2015. Four months after surgery, local relapse was found and the patient received a second surgery. After another 4 months, we found a hard mass in the right posterior neck when she admitted to our department for fourth cycle of adjuvant chemotherapy. Immunohistochemical investigation supported the diagnosis of glioblastoma metastases to the neck after resection of the right neck mass. A few days later, spinal vertebral magnetic resonance imaging (MRI) confirmed multiple metastases in the thoracic, lumbar, sacral, and bilateral iliac bones.


Glioblastoma is the most common primary malignant brain tumor. Whole tumor resection and early radiotherapy and chemotherapy can delay recurrence and prolong survival. Extracranial metastases are extremely rare. We report this case with the aim of bringing attention to extracranial metastasis of brain glioma.
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