Postoperative Hypoalbuminemia as a Predictor of Acute Kidney Injury After Open Repair of Ruptured Abdominal Aortic Aneurysm
- 20.09.2023
- Original Scientific Report
Erschienen in:
- Verfasst von
- Hei Jin Yoon
- Tae-Hoon Kim
- Da Eun Ko
- Jong-Wook Song
- Narhyun Min
- Sung Yeon Ham
- Erschienen in
- World Journal of Surgery | Ausgabe 12/2023
Abstract
Background
Perioperative hypoalbuminemia has a prognostic effect on mortality and morbidity in various cohorts. Patients undergoing open repair of ruptured abdominal aortic aneurysms (rAAA) are at a high risk of hypoalbuminemia due to bleeding and underlying diseases. Hence, this study aimed to investigate the predictive value of immediate postoperative hypoalbuminemia for the risk for acute kidney injury (AKI) in patients undergoing open rAAA repair.
Methods
We retrospectively reviewed 143 patients who underwent open rAAA repair between January 2008 and May 2022. The patients were divided into two groups according to the presence of postoperative AKI. The perioperative serum albumin levels of the two groups were compared. The patients were further divided into two groups based on the median immediate postoperative albumin level (2.4 g/dL). The incidence of AKI was compared between the two groups. Multivariate logistic regression analysis was performed to assess the predictors of postoperative AKI. Kaplan-Meier survival curves were used to evaluate potential of AKI and albumin level as prognostic factors for mortality.
Results
Immediate postoperative serum albumin was significantly lower in the AKI group than in the non-AKI group (2.11 ± 0.62 g/dL vs. 2.59 ± 0.62 g/dL, p < 0.001). The incidence of postoperative AKI was significantly higher in patients with albumin ≤ 2.4 g/dL than in patients with albumin > 2.4 g/dL (53.8% vs. 27.7%, p = 0.002). Immediate postoperative albumin level was an independent predictor of AKI (Odds ratio [OR], 0.310; 95% confidence interval [CI] 0.165–0.583, p < 0.001) and 1-year mortality (OR, 0.230; 95% CI 0.098–0.542, p = 0.001).
Conclusions
Immediate postoperative hypoalbuminemia was associated with postoperative AKI and mortality in patients with rAAA.
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- Titel
- Postoperative Hypoalbuminemia as a Predictor of Acute Kidney Injury After Open Repair of Ruptured Abdominal Aortic Aneurysm
- Verfasst von
-
Hei Jin Yoon
Tae-Hoon Kim
Da Eun Ko
Jong-Wook Song
Narhyun Min
Sung Yeon Ham
- Publikationsdatum
- 20.09.2023
- Verlag
- Springer International Publishing
- Erschienen in
-
World Journal of Surgery / Ausgabe 12/2023
Print ISSN: 0364-2313
Elektronische ISSN: 1432-2323 - DOI
- https://doi.org/10.1007/s00268-023-07178-z
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