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Erschienen in: Langenbeck's Archives of Surgery 6/2013

01.08.2013 | Original Article

Postoperative peripheral blood monocyte count correlates with postoperative bile leakage in patients with colorectal liver metastases after hepatic resection

verfasst von: Koichiro Haruki, Hiroaki Shiba, Yuki Fujiwara, Kenei Furukawa, Shigeki Wakiyama, Masaichi Ogawa, Yuichi Ishida, Takeyuki Misawa, Katsuhiko Yanaga

Erschienen in: Langenbeck's Archives of Surgery | Ausgabe 6/2013

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Abstract

Purpose

Postoperative bile leakage is one of the most common complications after hepatic surgery. The relationship between the inflammatory response and postoperative bile leakage has not been fully investigated. Therefore, we retrospectively investigated the relation between postoperative peripheral blood monocyte count and bile leakage in patients with colorectal liver metastases (CRLM) after elective hepatic resection.

Methods

The study comprised 105 patients who had undergone hepatic resection for CRLM between January 2000 and March 2012. Perioperative risk factors pertinent to development of bile leakage were investigated using univariate and multivariate analyses.

Results

Bile leakage developed in 9 (8.6 %) of 105 patients. In multivariate analysis, intraoperative fresh frozen plasma (FFP) transfusion (p = 0.009) and lower monocyte count of the peripheral blood on postoperative day 1 (p = 0.038) were found as independent risk factors of bile leakage.

Conclusions

Postoperative lower monocyte count and intraoperative FFP transfusion were associated with the development of postoperative bile leakage after elective hepatic resection in patients with CRLM.
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Metadaten
Titel
Postoperative peripheral blood monocyte count correlates with postoperative bile leakage in patients with colorectal liver metastases after hepatic resection
verfasst von
Koichiro Haruki
Hiroaki Shiba
Yuki Fujiwara
Kenei Furukawa
Shigeki Wakiyama
Masaichi Ogawa
Yuichi Ishida
Takeyuki Misawa
Katsuhiko Yanaga
Publikationsdatum
01.08.2013
Verlag
Springer Berlin Heidelberg
Erschienen in
Langenbeck's Archives of Surgery / Ausgabe 6/2013
Print ISSN: 1435-2443
Elektronische ISSN: 1435-2451
DOI
https://doi.org/10.1007/s00423-013-1083-4

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