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Erschienen in: European Journal of Nutrition 8/2016

26.09.2015 | Original Contribution

Postprandial insulin and glucose levels are reduced in healthy subjects when a standardised breakfast meal is supplemented with a filtered sugarcane molasses concentrate

verfasst von: Timothy P. Ellis, Alison G. Wright, Peter M. Clifton, Leodevico L. Ilag

Erschienen in: European Journal of Nutrition | Ausgabe 8/2016

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Abstract

Purpose

A phytochemical- and mineral-rich filtered sugarcane molasses concentrate (FMC), when added to carbohydrate-containing foods as a functional ingredient, lowers postprandial blood glucose and insulin responses. We hypothesised that this beneficial effect would also occur if FMC was administered as an oral supplement taken before a meal.

Methods

This study measured the postprandial glucose and insulin responses elicited by different doses of FMC administered immediately prior to a standard breakfast to healthy subjects. Each subject was given three or five breakfast meals once, on different days. The composition of the meals was identical, except for the addition of either placebo syrup (test meal 1) or increasing doses of FMC (test meals 2–5).

Results

The plasma glucose concentration curves were similar for the five test meals. Plasma insulin curves were lowered in a dose-dependent manner. Stratifying subjects based on age, BMI and insulin resistance showed greater effects of low doses of FMC on lowering insulin responses in those subjects with potentially greater insulin resistance. When insulin response is standardised to amount of carbohydrate in the meal/dose combination, the reduction in response is linear and inversely proportional to the FMC dose.

Conclusions

FMC shows promise as an agent that can reduce insulin responses and lessen the load on the pancreatic beta cells.
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Metadaten
Titel
Postprandial insulin and glucose levels are reduced in healthy subjects when a standardised breakfast meal is supplemented with a filtered sugarcane molasses concentrate
verfasst von
Timothy P. Ellis
Alison G. Wright
Peter M. Clifton
Leodevico L. Ilag
Publikationsdatum
26.09.2015
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Nutrition / Ausgabe 8/2016
Print ISSN: 1436-6207
Elektronische ISSN: 1436-6215
DOI
https://doi.org/10.1007/s00394-015-1043-6

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