Obesity and obesity-related conditions, such as type 2 diabetes, are a major issue for Veteran health. Veterans Health Administration (VA) researchers and health systems leaders have worked separately and together to provide more effective weight management programs for Veterans. Although randomized clinical trials are often considered the gold standard for establishing efficacy of interventions in controlled circumstances, pragmatic clinical trials (PCTs) provide agility for translation.
VA researchers and health system leaders collaboratively designed a PCT to compare the Diabetes Prevention Program (VA-DPP) to usual care (MOVE!®) in promoting weight loss and glycemic control among overweight/obese Veterans with prediabetes. Together, they navigated the tensions that exist between quality improvement and research activities, facing challenges but reaping significant rewards. Early findings led to updated national guidance for delivering obesity treatment in VA.
Partnered research and the use of PCTs can be powerful strategies for accelerating evidence-based findings into practice. Collaborative partnerships between researchers and health systems leaders can help enhance and sustain translation in real-world settings.
IOM (Institute of Medicine). Psychosocial interventions for mental and substance use disorders: A framework for establishing evidence-based standards. Washington, DC: The National Academies Press; 2015.
Diabetes Prevention Program Research G. Long-term effects of lifestyle intervention or metformin on diabetes development and microvascular complications over 15-year follow-up: the Diabetes Prevention Program Outcomes Study. Lancet Diabetes Endocrinol. 2015;3(11):866–75. CrossRef
Diabetes Prevention Program Research G, Knowler WC, Fowler SE, Hamman RF, Christophi CA, Hoffman HJ, Brenneman AT, Brown-Friday JO, Goldberg R, Venditti E, et al. 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet. 2009;374(9702):1677–86. CrossRef
Ali MK, Echouffo-Tcheugui J, Williamson DF. How effective were lifestyle interventions in real-world settings that were modeled on the Diabetes Prevention Program? Health Aff (Millwood). 2012;31(1):67–75. CrossRef
Damschroder LJ, Reardon CM, Sperber N, Robinson CH, Fickel JJ, Oddone EZ. Implementation evaluation of the telephone lifestyle coaching (TLC) program: organizational factors associated with successful implementation. Transl Behav Med . In press.
Petzel RA. VHA Operations Activities That May Constitute Research. Washington: In. Edited by Affairs DoV; 2011.
Moin T, Damschroder LJ, AuYoung M, Maciejewski ML, Datta SK, Weinreb JE, Steinle N, Billington C, Hughes M, Makki F, et al. Diabetes prevention program translation in the veterans health administration. American Journal of Preventive Medicine. In press.
Damschroder LJ, Moin T, Datta SK, Reardon CM, Steinle N, Weinreb J, Billington CJ, Maciejewski ML, Yancy Jr WS, Hughes M, et al. Implementation and evaluation of the VA DPP clinical demonstration: protocol for a multi-site non-randomized hybrid effectiveness-implementation type III trial. Implementation science : IS. 2015;10:68. CrossRefPubMedPubMedCentral
Moin T., Damschroder LJ, Youles B., Makki F, Billington C, Yancy W, Maciejewski ML, Kinsinger LS, Weinreb J, Steinle NE, et al. Implementation of a prediabetes identification algorithm for overweight and obese Veterans. J Rehabil Res Dev . In press.
Moin T, Richardson CR, Damschroder LJ. Implementing diabetes prevention in the VA: results from a clinical demonstration project. San Antonio: Paper presented at Society of Behavioral Medicine Annual Meeting and Scientific Sessions; 2015.
Damschroder LJ, Reardon CM, AuYoung M, Moin T, Datta SK, Sparks JB, Maciejewski ML, Steinle N, Weinreb JE, Hughes M. et al. Evaluation of the VA Diabetes Prevention Program (VA-DPP) Clinical Demonstration in the Veterans Health Administration (VHA): Implementation Findings. Under review.
Mador J. New VA program targets diabetes in vets, MPR News. 2012.
Kinsinger LS. Disease prevention in the Veterans Health Administration. N C Med J. 2015;76(5):335–8. PubMed
- Practical partnered research to improve weight loss among overweight/obese veterans: lessons from the trenches
Laura J. Damschroder
Caroline R. Richardson
- BioMed Central
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