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01.03.2013 | Research Article | Ausgabe 3/2013

Clinical and Translational Oncology 3/2013

Practice patterns in the management of prostate cancer in Spain: results from a national survey among radiation oncologists in 2009

Zeitschrift:
Clinical and Translational Oncology > Ausgabe 3/2013
Autoren:
Almudena Zapatero, José López-Torrecilla, Ismael Herruzo, Felipe A. Calvo, SEOR URONCOR GICOR participating Investigators
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1007/​s12094-012-0913-0) contains supplementary material, which is available to authorized users.

Abstract

Introduction

Little is known of practice patterns on advanced prostate cancer (PC) in Spain. The study objectives were to investigate practice patterns in the management of PC and to determine the adherence to the 2007 Spanish guidelines for the management of PC.

Materials and methods

An epidemiological, cross-sectional study was undertaken. Study-specific questionnaires were distributed to all centers with radiation oncology (RO) facilities delivering megavoltage radiation therapy (RT) in Spain (n = 108). A questionnaire evaluated diagnostic and treatment approaches to PC in low-risk and high-risk cases. And a 12-item questionnaire was used to assess guidelines adherence.

Results

Responses were obtained from 102 centers (94.0 % response rate). In the high-risk scenario, the majority of clinicians (99.0 %) chose combined modality treatment with RT and androgen deprivation (AD) and 93.0 % recommended long-term AD. External-beam RT (EBRT) doses ranging 72–76 Gy were used in 59.5 % of centers and >76 Gy was employed in 40.5 %. In the low-risk scenario, EBRT was chosen by 59.6 %, brachytherapy by 39.4 %, and active surveillance by 1 %. The consensus was high (score 5 + 4 ≥ 90 %) on 8/12 questions assessing adherence to guidelines, being high specifically on items related to RT technique, RT dose, combination of HT and RT in intermediate/high-risk patients, and prognostic factors.

Conclusions

This is the largest survey to date of Spanish RO departments dealing with PC. The study results therefore likely provide a highly reliable picture of clinical practice in Spain in this century and show how this practice is influenced by clinical evidence from randomized trials and consensus conferences.

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