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Erschienen in: Annals of Surgical Oncology 11/2019

11.06.2019 | Breast Oncology

Practitioner Opinion on Contralateral Prophylactic Mastectomy: How Do We Steer a Patient-Driven Discussion?

verfasst von: Angela E. Schellenberg, MD, Amanda Stypulkowski, BSc, Erin Cordeiro, MD, Claire M. B. Holloway, MD, Andrea Eisen, MD, Adena S. Scheer, MD

Erschienen in: Annals of Surgical Oncology | Ausgabe 11/2019

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Abstract

Background

Contralateral prophylactic mastectomy (CPM) is increasing despite a recent statement from The American Society of Breast Surgeons discouraging average-risk women with unilateral breast cancer (BC) from undergoing CPM. The objective of our study was to conduct a needs assessment of BC health practitioners to gather information about their opinions, attitudes, and experiences surrounding CPM.

Methods

The Ottawa Decision Support Framework was the theoretical framework for the development of the interview guide. Semistructured interviews were conducted until data saturation with a convenience sample of 16 BC practitioners (Ontario, Canada), including oncologic and reconstructive surgeons, medical oncologists, and nurse navigators.

Results

Nearly all practitioners identified the discussion regarding CPM as patient-initiated. The majority of practitioners (13/16) described their role as supporting the patient in the decision-making process. Practitioners described educating patients on the lack of survival benefit and in general discouraging CPM. Practitioners agreed that most patients demonstrate decisional conflict (11/16) as a barrier to decision-making, and it is a challenge to realign patients’ understanding and expectations. Almost all practitioners (15/16) identified a need for information materials to help educate patients on the risks and benefits of CPM and to help realign expectations.

Conclusions

Practitioners have identified CPM in average-risk women with unilateral BC as a patient-driven phenomenon that is on the rise, despite highlighting the increased risk of complications and lack of survival benefit. Our practitioner needs assessment identifies the need for a dynamic decision aid to help guide the shared decision-making process for practitioners and patients.
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Literatur
1.
Zurück zum Zitat Healey EA, Cook EF, Orav EJ, Schnitt SJ, Connolly JL, Harris JR. Contralateral breast cancer: clinical characteristics and impact on prognosis. J Clin Oncol. 1993;11(8):1545–52.CrossRefPubMed Healey EA, Cook EF, Orav EJ, Schnitt SJ, Connolly JL, Harris JR. Contralateral breast cancer: clinical characteristics and impact on prognosis. J Clin Oncol. 1993;11(8):1545–52.CrossRefPubMed
2.
Zurück zum Zitat Kollias J, Ellis IO, Elston CW, Blamey RW. Clinical and histological predictors of contralateral breast cancer. Eur J Surg Oncol. 1999;25(6):584–9.CrossRefPubMed Kollias J, Ellis IO, Elston CW, Blamey RW. Clinical and histological predictors of contralateral breast cancer. Eur J Surg Oncol. 1999;25(6):584–9.CrossRefPubMed
3.
Zurück zum Zitat Dragun AE, Pan J, Riley EC, Kruse B, Wilson MR, Rai S, Dharamvir J. Increasing use of elective mastectomy and contralateral prophylactic surgery among breast conservation candidates: a 14-year report from a comprehensive cancer center. Am J Clin Oncol. 2013;36(4):375–80.CrossRefPubMed Dragun AE, Pan J, Riley EC, Kruse B, Wilson MR, Rai S, Dharamvir J. Increasing use of elective mastectomy and contralateral prophylactic surgery among breast conservation candidates: a 14-year report from a comprehensive cancer center. Am J Clin Oncol. 2013;36(4):375–80.CrossRefPubMed
4.
Zurück zum Zitat Jones NB, Wilson J, Kotur L, Stephens J, Farrar WB, Agnese DM. Contralateral prophylactic mastectomy for unilateral breast cancer: an increasing trend at a single institution. Ann Surg Oncol. 2009;16:2691–6.CrossRefPubMed Jones NB, Wilson J, Kotur L, Stephens J, Farrar WB, Agnese DM. Contralateral prophylactic mastectomy for unilateral breast cancer: an increasing trend at a single institution. Ann Surg Oncol. 2009;16:2691–6.CrossRefPubMed
5.
Zurück zum Zitat Guilfoyle C, Christoudias M, Collett AE, Gracely EJ, Frazier TG, Barrio AV. Effect of preoperative MRI on mastectomy and contralateral prophylactic mastectomy rates at a community hospital by a single surgeon. Breast J. 2014;20(1):79–83.CrossRefPubMed Guilfoyle C, Christoudias M, Collett AE, Gracely EJ, Frazier TG, Barrio AV. Effect of preoperative MRI on mastectomy and contralateral prophylactic mastectomy rates at a community hospital by a single surgeon. Breast J. 2014;20(1):79–83.CrossRefPubMed
6.
Zurück zum Zitat King TA, Sakr R, Patil S, Gurevich I, Stempel M, Sampson M, Morrow M. Clinical management factors contribute to the decision for contralateral prophylactic mastectomy. J Clin Oncol. 2011;29(16):2158–64.CrossRefPubMed King TA, Sakr R, Patil S, Gurevich I, Stempel M, Sampson M, Morrow M. Clinical management factors contribute to the decision for contralateral prophylactic mastectomy. J Clin Oncol. 2011;29(16):2158–64.CrossRefPubMed
7.
Zurück zum Zitat Rosenberg S, Michaela T, Meyer M, et al. Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey. Ann Intern Med. 2013;159(6):373–81.CrossRefPubMedPubMedCentral Rosenberg S, Michaela T, Meyer M, et al. Perceptions, knowledge, and satisfaction with contralateral prophylactic mastectomy among young women with breast cancer: a cross-sectional survey. Ann Intern Med. 2013;159(6):373–81.CrossRefPubMedPubMedCentral
8.
Zurück zum Zitat Carbine NE, Lostumbo L, Wallace J, Ko H. Risk-reducing mastectomy for the prevention of primary breast cancer. Cochrane Database Syst Rev. 2018;4:CD002748. Carbine NE, Lostumbo L, Wallace J, Ko H. Risk-reducing mastectomy for the prevention of primary breast cancer. Cochrane Database Syst Rev. 2018;4:CD002748.
9.
Zurück zum Zitat Chung A, Huynh K, Lawrence C, Sim MS, Giuliano A. Comparison of patient characteristics and outcomes of contralateral prophylactic mastectomy and unilateral total mastectomy in breast cancer patients. Ann Surg Oncol. 2012;19(8):2600–6.CrossRefPubMed Chung A, Huynh K, Lawrence C, Sim MS, Giuliano A. Comparison of patient characteristics and outcomes of contralateral prophylactic mastectomy and unilateral total mastectomy in breast cancer patients. Ann Surg Oncol. 2012;19(8):2600–6.CrossRefPubMed
10.
Zurück zum Zitat Geiger AM, West CN, Nekhlyudov L, et al. Contentment with quality of life among breast cancer survivors with and without contralateral prophylactic mastectomy. J Clin Oncol. 2006;24(9):1350–6.CrossRefPubMed Geiger AM, West CN, Nekhlyudov L, et al. Contentment with quality of life among breast cancer survivors with and without contralateral prophylactic mastectomy. J Clin Oncol. 2006;24(9):1350–6.CrossRefPubMed
11.
Zurück zum Zitat Boughey JC, Attai DJ, Chen SL, et al. Contralateral prophylactic mastectomy consensus statement from the American Society of Breast Surgeons: additional considerations and a framework for shared decision making. Ann Surg Oncol. 2016;23:3106–11.CrossRefPubMedPubMedCentral Boughey JC, Attai DJ, Chen SL, et al. Contralateral prophylactic mastectomy consensus statement from the American Society of Breast Surgeons: additional considerations and a framework for shared decision making. Ann Surg Oncol. 2016;23:3106–11.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Boughey JC, Attai DJ, Chen SL, et al. Contralateral prophylactic mastectomy (CPM) consensus statement from the American Society of Breast Surgeons: Data on CPM outcomes and risks. Ann Surg Oncol. 2016;23:3100–5.CrossRefPubMedPubMedCentral Boughey JC, Attai DJ, Chen SL, et al. Contralateral prophylactic mastectomy (CPM) consensus statement from the American Society of Breast Surgeons: Data on CPM outcomes and risks. Ann Surg Oncol. 2016;23:3100–5.CrossRefPubMedPubMedCentral
14.
Zurück zum Zitat Parker PA, Peterson SK, Bedrosian I, et al. Prospective study of surgical decision-making processes for contralateral prophylactic mastectomy in women with breast cancer. Ann Surg. 2016;263(1):178–83.CrossRefPubMedPubMedCentral Parker PA, Peterson SK, Bedrosian I, et al. Prospective study of surgical decision-making processes for contralateral prophylactic mastectomy in women with breast cancer. Ann Surg. 2016;263(1):178–83.CrossRefPubMedPubMedCentral
15.
Zurück zum Zitat Venetis MK, MacGeorge EL, Baptiste DF, et al. Social network, surgeon, and media influence on the decision to undergo contralateral prophylactic mastectomy. Am J Clin Oncol. 2018;41:519–25.CrossRefPubMed Venetis MK, MacGeorge EL, Baptiste DF, et al. Social network, surgeon, and media influence on the decision to undergo contralateral prophylactic mastectomy. Am J Clin Oncol. 2018;41:519–25.CrossRefPubMed
16.
Zurück zum Zitat Jagsi R, Hawley ST, Griffith KA, et al. Contralateral prophylactic mastectomy decisions in a population-based sample of patients with early-stage breast cancer. JAMA Surg. 2017;152(3):274–82.CrossRefPubMedPubMedCentral Jagsi R, Hawley ST, Griffith KA, et al. Contralateral prophylactic mastectomy decisions in a population-based sample of patients with early-stage breast cancer. JAMA Surg. 2017;152(3):274–82.CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Abbott A, Rueth N, Pappas-Varco S, Kuntz K, Kerr E, Tuttle T. Perceptions of contralateral breast cancer: an overestimation of risk. Ann Surg Oncol. 2011;18:3129–36.CrossRefPubMed Abbott A, Rueth N, Pappas-Varco S, Kuntz K, Kerr E, Tuttle T. Perceptions of contralateral breast cancer: an overestimation of risk. Ann Surg Oncol. 2011;18:3129–36.CrossRefPubMed
18.
Zurück zum Zitat Bellavance E, Peppercorn J, Kronsberg S, et al. Surgeons’ perspectives of contralateral prophylactic mastectomy. Ann Surg Oncol. 2016;23:2779–87.CrossRefPubMed Bellavance E, Peppercorn J, Kronsberg S, et al. Surgeons’ perspectives of contralateral prophylactic mastectomy. Ann Surg Oncol. 2016;23:2779–87.CrossRefPubMed
19.
Zurück zum Zitat Gao X, Fisher S, Emami B. Risk of second primary cancer in the contralateral breast in women treated for early-stage breast cancer: a population-based study. Int J Radiat Oncol Biol Phys. 2003;56(4):1038–45.CrossRefPubMed Gao X, Fisher S, Emami B. Risk of second primary cancer in the contralateral breast in women treated for early-stage breast cancer: a population-based study. Int J Radiat Oncol Biol Phys. 2003;56(4):1038–45.CrossRefPubMed
20.
Zurück zum Zitat Covelli AM, Baxter NN, Fitch MI, McCready DR, Wright FC. Taking control of cancer: understanding women’s choice for mastectomy. Ann Surg Oncol. 2015;22:383–91.CrossRefPubMed Covelli AM, Baxter NN, Fitch MI, McCready DR, Wright FC. Taking control of cancer: understanding women’s choice for mastectomy. Ann Surg Oncol. 2015;22:383–91.CrossRefPubMed
21.
Zurück zum Zitat Musiello T, Bornhammar E, Saunders C. Breast surgeons’ perceptions and attitudes towards contralateral prophylactic mastectomy. ANZ J Surg. 2013;83:527–532.CrossRefPubMed Musiello T, Bornhammar E, Saunders C. Breast surgeons’ perceptions and attitudes towards contralateral prophylactic mastectomy. ANZ J Surg. 2013;83:527–532.CrossRefPubMed
22.
Zurück zum Zitat Arrington AK, Jarosek SL, Virnig BA, Habermann EB, Tuttle TM. Patient and surgeon characteristics associated with increased use of contralateral prophylactic mastectomy in patients with breast cancer. Ann Surg Oncol. 2009;16:2697–704.CrossRefPubMed Arrington AK, Jarosek SL, Virnig BA, Habermann EB, Tuttle TM. Patient and surgeon characteristics associated with increased use of contralateral prophylactic mastectomy in patients with breast cancer. Ann Surg Oncol. 2009;16:2697–704.CrossRefPubMed
23.
Zurück zum Zitat Agarwal S, Kidwell KM, Kraft CT, Kozlow JH, Sabel MS, Chung KC, Momoh AO. Defining the relationship between patient decisions to undergo breast reconstruction and contralateral prophylactic mastectomy. Plast Reconstr Surg. 2015;135:661–70.CrossRefPubMedPubMedCentral Agarwal S, Kidwell KM, Kraft CT, Kozlow JH, Sabel MS, Chung KC, Momoh AO. Defining the relationship between patient decisions to undergo breast reconstruction and contralateral prophylactic mastectomy. Plast Reconstr Surg. 2015;135:661–70.CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Ashfaq A, McGhan LJ, Pockaj BA, et al. Impact of breast reconstruction on the decision to undergo contralateral prophylactic mastectomy. Ann Surg Oncol. 2014;21:2934–40.CrossRefPubMed Ashfaq A, McGhan LJ, Pockaj BA, et al. Impact of breast reconstruction on the decision to undergo contralateral prophylactic mastectomy. Ann Surg Oncol. 2014;21:2934–40.CrossRefPubMed
25.
Zurück zum Zitat Boughey JC, Schilz SR, Van Houten HK, Zhu L, Habermann EB, Lemaine V. Contralateral prophylactic mastectomy with immediate breast reconstruction increases healthcare utilization and cost. Ann Surg Oncol. 2017;24(10):2957–64.CrossRefPubMed Boughey JC, Schilz SR, Van Houten HK, Zhu L, Habermann EB, Lemaine V. Contralateral prophylactic mastectomy with immediate breast reconstruction increases healthcare utilization and cost. Ann Surg Oncol. 2017;24(10):2957–64.CrossRefPubMed
26.
Zurück zum Zitat Billig JI, Duncan A, Zhong L, et al. The cost of contralateral prophylactic mastectomy in women with unilateral breast cancer. Plast Reconstr Surg. 2018;141(5):1094–102.CrossRefPubMedPubMedCentral Billig JI, Duncan A, Zhong L, et al. The cost of contralateral prophylactic mastectomy in women with unilateral breast cancer. Plast Reconstr Surg. 2018;141(5):1094–102.CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Miller ME, Czechura T, Martz B, et al. Operative risks associated with contralateral prophylactic mastectomy: a single institution experience. Ann Surg Oncol. 2013;20:4113–20.CrossRefPubMed Miller ME, Czechura T, Martz B, et al. Operative risks associated with contralateral prophylactic mastectomy: a single institution experience. Ann Surg Oncol. 2013;20:4113–20.CrossRefPubMed
28.
Zurück zum Zitat Osman F, Saleh F, Jackson TD, Corrigan MA, Cil T. Increased postoperative complications in bilateral mastectomy patients compared to unilateral mastectomy: an analysis of the NSQIP database. Ann Surg Oncol. 2013;20:3212–7.CrossRefPubMed Osman F, Saleh F, Jackson TD, Corrigan MA, Cil T. Increased postoperative complications in bilateral mastectomy patients compared to unilateral mastectomy: an analysis of the NSQIP database. Ann Surg Oncol. 2013;20:3212–7.CrossRefPubMed
29.
Zurück zum Zitat Fayanju OM, Stoll CRT, Fowler S, Colditz GA, Margenthaler JA. Contralateral prophylactic mastectomy after unilateral breast cancer: a systematic review and meta-analysis. Ann Surg. 2014;260:1000–10.CrossRefPubMedPubMedCentral Fayanju OM, Stoll CRT, Fowler S, Colditz GA, Margenthaler JA. Contralateral prophylactic mastectomy after unilateral breast cancer: a systematic review and meta-analysis. Ann Surg. 2014;260:1000–10.CrossRefPubMedPubMedCentral
Metadaten
Titel
Practitioner Opinion on Contralateral Prophylactic Mastectomy: How Do We Steer a Patient-Driven Discussion?
verfasst von
Angela E. Schellenberg, MD
Amanda Stypulkowski, BSc
Erin Cordeiro, MD
Claire M. B. Holloway, MD
Andrea Eisen, MD
Adena S. Scheer, MD
Publikationsdatum
11.06.2019
Verlag
Springer International Publishing
Erschienen in
Annals of Surgical Oncology / Ausgabe 11/2019
Print ISSN: 1068-9265
Elektronische ISSN: 1534-4681
DOI
https://doi.org/10.1245/s10434-019-07432-6

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