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Erschienen in: European Radiology 10/2020

04.05.2020 | Hepatobiliary-Pancreas

Prediction of HCC microvascular invasion with gadobenate-enhanced MRI: correlation with pathology

verfasst von: Ling Zhang, Xian Yu, WenXin Wei, XingPeng Pan, Lun Lu, JinJu Xia, Wei Zheng, Ningyang Jia, Lei Huo

Erschienen in: European Radiology | Ausgabe 10/2020

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Abstract

Purpose

To assess the accuracy of gadobenate-enhanced MRI for predicting microvascular invasion (MVI) in patients operated for hepatocellular carcinoma (HCC).

Methods

The 164 patients who met the inclusion criteria were assigned to one of two groups: the MVI-positive group and the MVI-negative group. Imaging results were compared between the two groups using the Kruskal test, chi-square test, independent sample t test, and logistic regression analysis.

Results

Differences in the capsule (p = 0.037) and margin (p = 0.004) of the tumor, rim enhancement (p = 0.002), peritumoral enhancement in the arterial phase (p < 0.001), and peritumoral hypointensity in the hepatobiliary phase (HBP) (p < 0.001) were statistically significant. The results of multivariate analysis identified rim enhancement in the arterial phase (odds ratio (OR) = 2.115; 95% confidence interval (CI), 1.002–4.464; p = 0.049) and peritumoral hypointensity in the HBP (OR = 5.836; 95% CI, 2.442–13.948; p < 0.001) as independent risk factors for MVI. Use of the two predictors in combination identified 32.79% (20/61) of HCCs with MVI with a specificity of 95.15% (98/103).

Conclusions

Rim enhancement in the arterial phase and peritumoral hypointensity in the HBP were identified as independent risk factors for MVI in patients with HCC.

Key Points

• Rim enhancement in the arterial phase and peritumoral hypointensity in the hepatobiliary phase were independent risk factors for microvascular invasion in patients with HCC.
• Use of the two predictors in combination had a sensitivity of 32.79% and a specificity of 95.15% for predicting microvascular invasion.
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Metadaten
Titel
Prediction of HCC microvascular invasion with gadobenate-enhanced MRI: correlation with pathology
verfasst von
Ling Zhang
Xian Yu
WenXin Wei
XingPeng Pan
Lun Lu
JinJu Xia
Wei Zheng
Ningyang Jia
Lei Huo
Publikationsdatum
04.05.2020
Verlag
Springer Berlin Heidelberg
Erschienen in
European Radiology / Ausgabe 10/2020
Print ISSN: 0938-7994
Elektronische ISSN: 1432-1084
DOI
https://doi.org/10.1007/s00330-020-06895-6

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