Erschienen in:
01.04.2019 | Original Article
Predictive value of 18F-FDG PET/CT in patients with acute type B aortic intramural hematoma
verfasst von:
Fan Yang, MD, Jianfang Luo, MD, Qingyi Hou, MD, Nianjin Xie, MD, Zhiqiang Nie, MD, Wenhui Huang, MD, Yuan Liu, MD, Yingling Zhou, MD, Jiyan Chen, MD, Qingshan Geng, MD
Erschienen in:
Journal of Nuclear Cardiology
|
Ausgabe 2/2019
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Abstract
Background
The clinical course and predictors of adverse aortic events (AAE) in patients with acute Stanford type B intramural hematoma (IMH) remain controversial. This study aimed to investigate whether 18F-FDG PET/CT can predict risk in patients with acute type B IMH.
Methods and Results
This study included 34 patients with acute type B IMH who underwent PET/CT within 14 days from the onset of symptoms. The maximal standardized uptake values (SUVmax) of 18F-FDG uptake was significantly different between patients with or without AAE (4.3 ± 0.6 vs 3.7 ± 1.0, P = 0.020), but not the target to blood ratio (TBR, SUVmax divided by SUV in the superior vena cava) (1.6 ± 0.2 vs 1.5 ± 0.5, P = 0.064). In patients with initial ulcer-like projection (ULP), a blood-filled pouch protruding into the IMH, which was seen in 25 patients(74%), both the SUVmax and TBR were significantly higher in patients who developed AAE, (4.3 ± 0.6 vs 3.3 ± 0.5, P = 0.001; 1.6 ± 0.2 vs 1.4 ± 0.2, P = 0.01); the TBR >1.5, which is determined from receiver-operating-characteristic curve, had a sensitivity of 73% and a specificity of 80% in predicting AAE.
Conclusion
Patients with ULP and high 18F-FDG uptake were more likely to develop AAE and may require closer surveillance with serial imaging.