Skip to main content

01.09.2020 | Coronary Heart Disease (S. Virani and S. Naderi, Section Editor) | Ausgabe 9/2020

Current Atherosclerosis Reports 9/2020

Premature Atherosclerotic Cardiovascular Disease: What Have We Learned Recently?

Current Atherosclerosis Reports > Ausgabe 9/2020
Dhruv Mahtta, Umair Khalid, Arunima Misra, Zainab Samad, Khurram Nasir, Salim S. Virani
Wichtige Hinweise
This article is part of the Topical Collection on Coronary Heart Disease

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.


Purpose of Review

In contrast to patients with non-premature atherosclerotic cardiovascular disease (ASCVD), patients with premature ASCVD have not observed a similar decline in cardiovascular mortality and recurrent adverse events. We sought to review the underlying risk factors, potential gaps in medical management, associated outcomes, and tools for risk prognostication among patients with premature ASCVD.

Recent Findings

In addition to traditional cardiovascular risk factors (i.e., diabetes, familial hypercholesterolemia), non-traditional risk factors such as chronic inflammatory conditions, recreational drug use, genetics, and pregnancy-related complications play a key role in development and progression of premature ASCVD. Patients with premature ASCVD, and especially women, receive less optimal medical management as compared to their non-premature counterparts.


There is an increasing prevalence of cardiovascular risk factors among young adults. Hence, this population remains at an elevated risk for premature ASCVD and subsequent adverse cardiovascular events. Future studies evaluating different risk assessment tools and focusing on young patients across all three major domains of ASCVD are needed.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

e.Med Interdisziplinär

Für Ihren Erfolg in Klinik und Praxis - Die beste Hilfe in Ihrem Arbeitsalltag als Mediziner

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf

Über diesen Artikel

Weitere Artikel der Ausgabe 9/2020

Current Atherosclerosis Reports 9/2020 Zur Ausgabe

Statin Drugs (R. Ceska, Section Editor)

The Role of Statins in Current Guidelines

Evidence-Based Medicine, Clinical Trials and Their Interpretations (L. Roever,Section Editor)

Impact of Different Doses of Omega-3 Fatty Acids on Cardiovascular Outcomes: a Pairwise and Network Meta-analysis

Women and Ischemic Heart Disease (P. Kohli, Section Editor)

Spontaneous Coronary Artery Dissection: Latest Developments and New Frontiers

Neu im Fachgebiet Innere Medizin

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Innere Medizin und bleiben Sie gut informiert – ganz bequem per eMail.

© Springer Medizin