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Erschienen in: Current HIV/AIDS Reports 2/2018

19.02.2018 | The Science of Prevention (JD Stekler and J Baeten, Section Editors)

PrEP Stigma: Implicit and Explicit Drivers of Disparity

verfasst von: Sarit A. Golub

Erschienen in: Current HIV/AIDS Reports | Ausgabe 2/2018

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Abstract

Purpose of Review

Despite its promise as an HIV prevention strategy, PrEP uptake remains slow, especially among highest priority populations. One factor that may be impeding implementation and driving disparities is PrEP-related stigma. This paper reviews the role of PrEP-related stigma in PrEP access, adherence, and persistence and examines its antecedents and consequences.

Recent Findings

Although PrEP stigma is often experienced at the community level (i.e., by potential and current users), it can be reinforced and even amplified by public health programs, policy, and research. PrEP stigma disproportionately impacts disadvantaged groups and impedes scalability by influencing behavior of both patients and providers.

Summary

Reducing PrEP stigma and its negative impact on the epidemic requires a significant shift in perspective, language, and programs. Such a shift is necessary to ensure broader reach of PrEP as a prevention strategy and improve its utilization by the individuals who need it most.
Literatur
2.
Zurück zum Zitat Lemly DC, Shepherd BE, Hulgan T, Rebeiro P, Stinnette S, Blackwell RB, et al. Race and sex differences in antiretroviral therapy use and mortality among HIV-infected persons in care. J Infect Dis. 2009;199(7):991–8.CrossRefPubMed Lemly DC, Shepherd BE, Hulgan T, Rebeiro P, Stinnette S, Blackwell RB, et al. Race and sex differences in antiretroviral therapy use and mortality among HIV-infected persons in care. J Infect Dis. 2009;199(7):991–8.CrossRefPubMed
3.
Zurück zum Zitat Hess KL, Hu X, Lansky A, Mermin J, Hall HI. Lifetime risk of a diagnosis of HIV infection in the United States. Ann Epidemiol. 2017;27(4):238–43.CrossRefPubMedPubMedCentral Hess KL, Hu X, Lansky A, Mermin J, Hall HI. Lifetime risk of a diagnosis of HIV infection in the United States. Ann Epidemiol. 2017;27(4):238–43.CrossRefPubMedPubMedCentral
4.
Zurück zum Zitat Zablotska IB, Spelman T, Grulich A. 2015–a seminal year for HIV biomedical prevention. J Int AIDS Soc. 2015;18(1):1–3.CrossRef Zablotska IB, Spelman T, Grulich A. 2015–a seminal year for HIV biomedical prevention. J Int AIDS Soc. 2015;18(1):1–3.CrossRef
5.
Zurück zum Zitat Eaton LA, Matthews DD, Driffin DD, Bukowski L, Wilson PA, Stall RDA. Multi-US City assessment of awareness and uptake of pre-exposure prophylaxis (PrEP) for HIV prevention among black men and transgender women who have sex with men. Prev Sci. 2017;18(5):505–16.CrossRefPubMed Eaton LA, Matthews DD, Driffin DD, Bukowski L, Wilson PA, Stall RDA. Multi-US City assessment of awareness and uptake of pre-exposure prophylaxis (PrEP) for HIV prevention among black men and transgender women who have sex with men. Prev Sci. 2017;18(5):505–16.CrossRefPubMed
6.
Zurück zum Zitat Parsons JT, Rendina HJ, Lassiter JM, Whitfield TH, Starks TJ, Grov C. Uptake of HIV pre-exposure prophylaxis (PrEP) in a National Cohort of gay and bisexual men in the United States. JAIDS J Acquir Immune Defic Syndr. 2017;74(3):285–92.CrossRefPubMed Parsons JT, Rendina HJ, Lassiter JM, Whitfield TH, Starks TJ, Grov C. Uptake of HIV pre-exposure prophylaxis (PrEP) in a National Cohort of gay and bisexual men in the United States. JAIDS J Acquir Immune Defic Syndr. 2017;74(3):285–92.CrossRefPubMed
7.
Zurück zum Zitat Kuhns LM, Hotton AL, Schneider J, Garofalo R, Fujimoto K. Use of pre-exposure prophylaxis (PrEP) in young men who have sex with men is associated with race, sexual risk behavior and peer network size. AIDS Behav. 2017;21(5):1376–82.CrossRefPubMed Kuhns LM, Hotton AL, Schneider J, Garofalo R, Fujimoto K. Use of pre-exposure prophylaxis (PrEP) in young men who have sex with men is associated with race, sexual risk behavior and peer network size. AIDS Behav. 2017;21(5):1376–82.CrossRefPubMed
8.
Zurück zum Zitat Elopre L, Kudroff K, Westfall AO, Overton ET, Mugavero MJ. Brief report: the right people, right places, and right practices: disparities in PrEP access among African American men, women, and MSM in the deep south. J Acquir Immune Defic Syndr. 2017;74(1):56–9.CrossRefPubMed Elopre L, Kudroff K, Westfall AO, Overton ET, Mugavero MJ. Brief report: the right people, right places, and right practices: disparities in PrEP access among African American men, women, and MSM in the deep south. J Acquir Immune Defic Syndr. 2017;74(1):56–9.CrossRefPubMed
9.
Zurück zum Zitat Stigma EG. Notes on the management of spoiled identity. New York: Simon & Schuster Inc; 1963. Stigma EG. Notes on the management of spoiled identity. New York: Simon & Schuster Inc; 1963.
10.
Zurück zum Zitat Golub SA, Gamarel KE, Surace A. Demographic differences in PrEP–related stereotypes: implications for implementation. AIDS Behav. 2017;21(5):1229–35.CrossRefPubMed Golub SA, Gamarel KE, Surace A. Demographic differences in PrEP–related stereotypes: implications for implementation. AIDS Behav. 2017;21(5):1229–35.CrossRefPubMed
11.
Zurück zum Zitat Biello KB, Oldenburg CE, Mitty JA, Closson EF, Mayer KH, Safren SA, et al. The" safe sex" conundrum: anticipated stigma from sexual partners as a barrier to PrEP use among substance using MSM engaging in transactional sex. AIDS Behav. 2017;21(1):300–6.CrossRefPubMedPubMedCentral Biello KB, Oldenburg CE, Mitty JA, Closson EF, Mayer KH, Safren SA, et al. The" safe sex" conundrum: anticipated stigma from sexual partners as a barrier to PrEP use among substance using MSM engaging in transactional sex. AIDS Behav. 2017;21(1):300–6.CrossRefPubMedPubMedCentral
12.
Zurück zum Zitat Van der Elst EM, Mbogua J, Operario D, Mutua G, Kuo C, Mugo P, et al. High acceptability of HIV pre-exposure prophylaxis but challenges in adherence and use: qualitative insights from a phase I trial of intermittent and daily PrEP in at-risk populations in Kenya. AIDS Behav. 2013;17(6):2163–72. Van der Elst EM, Mbogua J, Operario D, Mutua G, Kuo C, Mugo P, et al. High acceptability of HIV pre-exposure prophylaxis but challenges in adherence and use: qualitative insights from a phase I trial of intermittent and daily PrEP in at-risk populations in Kenya. AIDS Behav. 2013;17(6):2163–72.
13.
Zurück zum Zitat Joint United Nations Programme on HIV/AIDS (UNAIDS). On the Fast-Track to end AIDS by 2030: Focus on location and population. Geneva: UNAIDS; 2015. Joint United Nations Programme on HIV/AIDS (UNAIDS). On the Fast-Track to end AIDS by 2030: Focus on location and population. Geneva: UNAIDS; 2015.
15.
Zurück zum Zitat •• Haire BG. Preexposure prophylaxis-related stigma: strategies to improve uptake and adherence–a narrative review. HIV/AIDS (Auckland, NZ). 2015;7:241. This paper provides and important review and analysis of the PrEP stigma literature. •• Haire BG. Preexposure prophylaxis-related stigma: strategies to improve uptake and adherence–a narrative review. HIV/AIDS (Auckland, NZ). 2015;7:241. This paper provides and important review and analysis of the PrEP stigma literature.
16.
Zurück zum Zitat Calabrese SK, Underhill K. How stigma surrounding the use of HIV Preexposure prophylaxis undermines prevention and pleasure: a call to destigmatize "Truvada whores". Am J Public Health. 2015;105(10):1960–4.CrossRefPubMedPubMedCentral Calabrese SK, Underhill K. How stigma surrounding the use of HIV Preexposure prophylaxis undermines prevention and pleasure: a call to destigmatize "Truvada whores". Am J Public Health. 2015;105(10):1960–4.CrossRefPubMedPubMedCentral
17.
Zurück zum Zitat Eaton LA, Kalichman SC, Price D, Finneran S, Allen A, Maksut J. Stigma and conspiracy beliefs related to pre-exposure prophylaxis (PrEP) and interest in using PrEP among black and white men and transgender women who have sex with men. AIDS Behav. 2017;21(5):1236–46.CrossRefPubMed Eaton LA, Kalichman SC, Price D, Finneran S, Allen A, Maksut J. Stigma and conspiracy beliefs related to pre-exposure prophylaxis (PrEP) and interest in using PrEP among black and white men and transgender women who have sex with men. AIDS Behav. 2017;21(5):1236–46.CrossRefPubMed
18.
Zurück zum Zitat Farhat D, Greene E, Paige MQ, Koblin BA, Frye V. Knowledge, stereotyped beliefs and attitudes around HIV chemoprophylaxis in two high HIV prevalence neighborhoods in new York City. AIDS Behav. 2017;21(5):1247–55.CrossRefPubMed Farhat D, Greene E, Paige MQ, Koblin BA, Frye V. Knowledge, stereotyped beliefs and attitudes around HIV chemoprophylaxis in two high HIV prevalence neighborhoods in new York City. AIDS Behav. 2017;21(5):1247–55.CrossRefPubMed
19.
Zurück zum Zitat •• Knight R, Small W, Carson A, Shoveller J. Complex and Conflicting Social Norms: Implications for Implementation of Future HIV Pre-Exposure Prophylaxis (PrEP) Interventions in Vancouver, Canada. PLoS One. 2016;11(1):e0146513. This qualitative study provides examples and analysis of the nature of PrEP stigma among a cohort of men under 25. CrossRefPubMedPubMedCentral •• Knight R, Small W, Carson A, Shoveller J. Complex and Conflicting Social Norms: Implications for Implementation of Future HIV Pre-Exposure Prophylaxis (PrEP) Interventions in Vancouver, Canada. PLoS One. 2016;11(1):e0146513. This qualitative study provides examples and analysis of the nature of PrEP stigma among a cohort of men under 25. CrossRefPubMedPubMedCentral
20.
Zurück zum Zitat Anderson PL, Glidden DV, Liu A, Buchbinder S, Lama JR, Guanira JV, et al. Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men. Sci Transl Med. 2012;4(151):151ra125.CrossRefPubMedPubMedCentral Anderson PL, Glidden DV, Liu A, Buchbinder S, Lama JR, Guanira JV, et al. Emtricitabine-tenofovir concentrations and pre-exposure prophylaxis efficacy in men who have sex with men. Sci Transl Med. 2012;4(151):151ra125.CrossRefPubMedPubMedCentral
21.
Zurück zum Zitat Smith DK, Herbst JH, Zhang X, Rose CE. Condom effectiveness for HIV prevention by consistency of use among men who have sex with men in the United States. JAIDS J Acquir Immune Defic Syndr. 2015;68(3):337–44.CrossRefPubMed Smith DK, Herbst JH, Zhang X, Rose CE. Condom effectiveness for HIV prevention by consistency of use among men who have sex with men in the United States. JAIDS J Acquir Immune Defic Syndr. 2015;68(3):337–44.CrossRefPubMed
22.
Zurück zum Zitat Sullivan PS, Salazar L, Buchbinder S, Sanchez TH. Estimating the proportion of HIV transmissions from main sex partners among men who have sex with men in five US cities. AIDS. 2009;23(9):1153–62.CrossRefPubMed Sullivan PS, Salazar L, Buchbinder S, Sanchez TH. Estimating the proportion of HIV transmissions from main sex partners among men who have sex with men in five US cities. AIDS. 2009;23(9):1153–62.CrossRefPubMed
23.
Zurück zum Zitat MacKellar DA, Valleroy LA, Secura GM, Behel S, Bingham T, Celentano DD, et al. Unrecognized HIV infection, risk behaviors, and perceptions of risk among young men who have sex with men: opportunities for advancing HIV prevention in the third decade of HIV/AIDS. JAIDS J Acquir Immune Defic Syndr. 2005;38(5):603–14.CrossRefPubMed MacKellar DA, Valleroy LA, Secura GM, Behel S, Bingham T, Celentano DD, et al. Unrecognized HIV infection, risk behaviors, and perceptions of risk among young men who have sex with men: opportunities for advancing HIV prevention in the third decade of HIV/AIDS. JAIDS J Acquir Immune Defic Syndr. 2005;38(5):603–14.CrossRefPubMed
24.
Zurück zum Zitat Young SD, Nussbaum AD, Monin B. Potential moral stigma and reactions to sexually transmitted diseases: evidence for a disjunction fallacy. Personal Soc Psychol Bull. 2007;33:789–99.CrossRef Young SD, Nussbaum AD, Monin B. Potential moral stigma and reactions to sexually transmitted diseases: evidence for a disjunction fallacy. Personal Soc Psychol Bull. 2007;33:789–99.CrossRef
25.
Zurück zum Zitat Weinstock H, Dale M, Linley L, Gwinn M. Unrecognized HIV infection among patients attending sexually transmitted disease clinics. Am J Public Health. 2002;92:280–3.CrossRefPubMedPubMedCentral Weinstock H, Dale M, Linley L, Gwinn M. Unrecognized HIV infection among patients attending sexually transmitted disease clinics. Am J Public Health. 2002;92:280–3.CrossRefPubMedPubMedCentral
26.
Zurück zum Zitat Earnshaw VA, Smith LR, Chaudoir SR, Lee IC, Copenhaver MM. Stereotypes about people living with HIV: implications for perceptions of HIV risk and testing frequency among at risk populations. AIDS Educ Prev. 2012;24:574–81.CrossRefPubMedPubMedCentral Earnshaw VA, Smith LR, Chaudoir SR, Lee IC, Copenhaver MM. Stereotypes about people living with HIV: implications for perceptions of HIV risk and testing frequency among at risk populations. AIDS Educ Prev. 2012;24:574–81.CrossRefPubMedPubMedCentral
27.
Zurück zum Zitat Golub SA, Gamarel KE. The impact of anticipated HIV stigma on delays in HIV testing behaviors: findings from a community-based sample of men who have sex with men and transgender women in new York City. AIDS Patient Care STDs. 2013;27(11):621–7.CrossRefPubMedPubMedCentral Golub SA, Gamarel KE. The impact of anticipated HIV stigma on delays in HIV testing behaviors: findings from a community-based sample of men who have sex with men and transgender women in new York City. AIDS Patient Care STDs. 2013;27(11):621–7.CrossRefPubMedPubMedCentral
28.
Zurück zum Zitat Gallagher T, Link L, Ramos M, Bottger E, Aberg J, Daskalakis D. Self-perception of HIV risk and candidacy for pre-exposure prophylaxis among men who have sex with men testing for HIV at commercial sex venues in new York City. LGBT Health. 2014;1(3):218–24.CrossRefPubMed Gallagher T, Link L, Ramos M, Bottger E, Aberg J, Daskalakis D. Self-perception of HIV risk and candidacy for pre-exposure prophylaxis among men who have sex with men testing for HIV at commercial sex venues in new York City. LGBT Health. 2014;1(3):218–24.CrossRefPubMed
29.
Zurück zum Zitat Mack N, Odhiambo J, Wong CM, Agot K. Barriers and facilitators to pre-exposure prophylaxis (PrEP) eligibility screening and ongoing HIV testing among target populations in Bondo and Rarieda, Kenya: results of a consultation with community stakeholders. BMC Heal Serv Res. 2014;14:231.CrossRef Mack N, Odhiambo J, Wong CM, Agot K. Barriers and facilitators to pre-exposure prophylaxis (PrEP) eligibility screening and ongoing HIV testing among target populations in Bondo and Rarieda, Kenya: results of a consultation with community stakeholders. BMC Heal Serv Res. 2014;14:231.CrossRef
30.
Zurück zum Zitat •• Peng P, Su S, Fairley CK, et al. A global estimate of the acceptability of pre-exposure prophylaxis for HIV among men who have sex with men: a systematic review and meta-analysis. AIDS Behav. 2017; https://doi.org/10.1007/s10461-017-1675-z. This meta-analysis reviews PrEP acceptability studies internationally. •• Peng P, Su S, Fairley CK, et al. A global estimate of the acceptability of pre-exposure prophylaxis for HIV among men who have sex with men: a systematic review and meta-analysis. AIDS Behav. 2017; https://​doi.​org/​10.​1007/​s10461-017-1675-z. This meta-analysis reviews PrEP acceptability studies internationally.
31.
Zurück zum Zitat Tangmunkongvorakul A, Chariyalertsak S, Amico KR, Saokhieo P, Wannalak V, Sangangamsakun T, et al. Facilitators and barriers to medication adherence in an HIV prevention study among men who have sex with men in the iPrEx study in Chiang Mai, Thailand. AIDS Care. 2013;25(8):961–7.CrossRefPubMed Tangmunkongvorakul A, Chariyalertsak S, Amico KR, Saokhieo P, Wannalak V, Sangangamsakun T, et al. Facilitators and barriers to medication adherence in an HIV prevention study among men who have sex with men in the iPrEx study in Chiang Mai, Thailand. AIDS Care. 2013;25(8):961–7.CrossRefPubMed
32.
Zurück zum Zitat Blake HC, Turan JM, Atkins G, Kempf MC, Clay OJ, Raper JL, et al. Interpersonal mechanisms contributing to the association between HIV-related internalized stigma and medication adherence. AIDS Behav. 2017;21(1):238–47.CrossRef Blake HC, Turan JM, Atkins G, Kempf MC, Clay OJ, Raper JL, et al. Interpersonal mechanisms contributing to the association between HIV-related internalized stigma and medication adherence. AIDS Behav. 2017;21(1):238–47.CrossRef
33.
Zurück zum Zitat Darlington CK, Hutson SP. Understanding HIV-related stigma among women in the southern United States: a literature review. AIDS Behav. 2017;21(1):12–26.CrossRefPubMed Darlington CK, Hutson SP. Understanding HIV-related stigma among women in the southern United States: a literature review. AIDS Behav. 2017;21(1):12–26.CrossRefPubMed
34.
Zurück zum Zitat Liu A, Cohen S, Follansbee S, Cohan D, Weber S, Sachdev D, et al. Early experiences implementing pre-exposure prophylaxis (PrEP) for HIV prevention in San Francisco. PLoS Med. 2014;11(3):e1001613.CrossRefPubMedPubMedCentral Liu A, Cohen S, Follansbee S, Cohan D, Weber S, Sachdev D, et al. Early experiences implementing pre-exposure prophylaxis (PrEP) for HIV prevention in San Francisco. PLoS Med. 2014;11(3):e1001613.CrossRefPubMedPubMedCentral
35.
Zurück zum Zitat Garcia J, Parker C, Parker RG, Wilson PA, Philbin M, Hirsch JS. Psychosocial implications of homophobia and HIV stigma in social support networks: insights for high-impact HIV prevention among black men who have sex with men. Health Educ Behav. 2016;3(2):217–25.CrossRef Garcia J, Parker C, Parker RG, Wilson PA, Philbin M, Hirsch JS. Psychosocial implications of homophobia and HIV stigma in social support networks: insights for high-impact HIV prevention among black men who have sex with men. Health Educ Behav. 2016;3(2):217–25.CrossRef
38.
Zurück zum Zitat Underhill K. Intimacy, condom use, and pre-exposure prophylaxis (PrEP) acceptability among men who have sex with men (MSM) in primary partnerships: a comment on Gamarel and Golub. Ann Behav Med. 2015;49(2):151–3.CrossRefPubMedPubMedCentral Underhill K. Intimacy, condom use, and pre-exposure prophylaxis (PrEP) acceptability among men who have sex with men (MSM) in primary partnerships: a comment on Gamarel and Golub. Ann Behav Med. 2015;49(2):151–3.CrossRefPubMedPubMedCentral
39.
Zurück zum Zitat Celum CL, Delany-Moretlwe S, McConnell M, Van Rooyen H, Bekker LG, Kurth A, et al. Rethinking HIV prevention to prepare for oral PrEP implementation for young African women. J Int AIDS Soc. 2015;18(4Suppl 3):20227.PubMedPubMedCentral Celum CL, Delany-Moretlwe S, McConnell M, Van Rooyen H, Bekker LG, Kurth A, et al. Rethinking HIV prevention to prepare for oral PrEP implementation for young African women. J Int AIDS Soc. 2015;18(4Suppl 3):20227.PubMedPubMedCentral
41.
Zurück zum Zitat Kowalewski MR, Henson KD, Longshore D. Rethinking perceived risk and health behavior: a critical review of HIV prevention research. Health Educ Behav. 1997;24(3):313–25.CrossRefPubMed Kowalewski MR, Henson KD, Longshore D. Rethinking perceived risk and health behavior: a critical review of HIV prevention research. Health Educ Behav. 1997;24(3):313–25.CrossRefPubMed
42.
Zurück zum Zitat MacKellar DA, Valleroy LA, Secura GM, Behel S, Bingham T, Celentano DD, et al. Perceptions of lifetime risk and actual risk for acquiring HIV among young men who have sex with men. AIDS Behav. 2007;11(2):263–70.CrossRefPubMed MacKellar DA, Valleroy LA, Secura GM, Behel S, Bingham T, Celentano DD, et al. Perceptions of lifetime risk and actual risk for acquiring HIV among young men who have sex with men. AIDS Behav. 2007;11(2):263–70.CrossRefPubMed
43.
Zurück zum Zitat Karris MY, Beekmann SE, Mehta SR, Anderson CM, Polgreen PM. Are we prepped for preexposure prophylaxis (PrEP)? Provider opinions on the real-world use of PrEP in the United States and Canada. Clin Infect Dis. 2014;58(5):704–12.CrossRefPubMed Karris MY, Beekmann SE, Mehta SR, Anderson CM, Polgreen PM. Are we prepped for preexposure prophylaxis (PrEP)? Provider opinions on the real-world use of PrEP in the United States and Canada. Clin Infect Dis. 2014;58(5):704–12.CrossRefPubMed
44.
Zurück zum Zitat Blackstock OJ, Moore BA, Berkenblit GV, Calabrese SK, Cunningham CO, Fiellin DA, et al. A cross-sectional online survey of HIV pre-exposure prophylaxis adoption among primary care physicians. J Gen Intern Med. 2017;32(1):62–70.CrossRefPubMed Blackstock OJ, Moore BA, Berkenblit GV, Calabrese SK, Cunningham CO, Fiellin DA, et al. A cross-sectional online survey of HIV pre-exposure prophylaxis adoption among primary care physicians. J Gen Intern Med. 2017;32(1):62–70.CrossRefPubMed
45.
Zurück zum Zitat Tripathi A, Ogbuanu C, Monger M, Gibson JJ, Duffus WA. Pre-exposure prophylaxis for HIV infection: healthcare providers’ knowledge, perception, and willingness to adopt future implementation in the southern US. South Med J. 2012;105(4):199–206.CrossRefPubMed Tripathi A, Ogbuanu C, Monger M, Gibson JJ, Duffus WA. Pre-exposure prophylaxis for HIV infection: healthcare providers’ knowledge, perception, and willingness to adopt future implementation in the southern US. South Med J. 2012;105(4):199–206.CrossRefPubMed
46.
Zurück zum Zitat Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587–99.CrossRefPubMedPubMedCentral Grant RM, Lama JR, Anderson PL, McMahan V, Liu AY, Vargas L, et al. Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med. 2010;363(27):2587–99.CrossRefPubMedPubMedCentral
47.
Zurück zum Zitat Jenness SM, Goodreau SM, Rosenberg E, Beylerian EN, Hoover KW, Smith DK, et al. Impact of the centers for disease Control's HIV preexposure prophylaxis guidelines for men who have sex with men in the United States. J Infect Dis. 2016;214(12):1800–7.CrossRefPubMedPubMedCentral Jenness SM, Goodreau SM, Rosenberg E, Beylerian EN, Hoover KW, Smith DK, et al. Impact of the centers for disease Control's HIV preexposure prophylaxis guidelines for men who have sex with men in the United States. J Infect Dis. 2016;214(12):1800–7.CrossRefPubMedPubMedCentral
48.
Zurück zum Zitat Volk JE, Marcus JL, Phengrasamy T, Blechinger D, Nguyen DP, Follansbee S, et al. No new HIV infections with increasing use of HIV preexposure prophylaxis in a clinical practice setting. Clin Infect Dis. 2015;61(10):1601–3.CrossRefPubMedPubMedCentral Volk JE, Marcus JL, Phengrasamy T, Blechinger D, Nguyen DP, Follansbee S, et al. No new HIV infections with increasing use of HIV preexposure prophylaxis in a clinical practice setting. Clin Infect Dis. 2015;61(10):1601–3.CrossRefPubMedPubMedCentral
49.
Zurück zum Zitat •• Jenness SM, Sharma A, Goodreau SM, Rosenberg ES, Weiss KM, Hoover KW, et al. Individual HIV Risk versus population impact of risk compensation after HIV Preexposure prophylaxis initiation among men who have sex with men. PloS one. 2017;12(1):e0169484. This modeling study examines the impact of changes in condom use among PrEP users and demonstrates that risk compensation may actually result in decreased HIV incidence. CrossRefPubMedPubMedCentral •• Jenness SM, Sharma A, Goodreau SM, Rosenberg ES, Weiss KM, Hoover KW, et al. Individual HIV Risk versus population impact of risk compensation after HIV Preexposure prophylaxis initiation among men who have sex with men. PloS one. 2017;12(1):e0169484. This modeling study examines the impact of changes in condom use among PrEP users and demonstrates that risk compensation may actually result in decreased HIV incidence. CrossRefPubMedPubMedCentral
50.
Zurück zum Zitat Alaei K, Paynter CA, Juan SC, Alaei A. Using preexposure prophylaxis, losing condoms? Preexposure prophylaxis promotion may undermine safe sex. AIDS. 2016;30(18):2753–6.CrossRefPubMed Alaei K, Paynter CA, Juan SC, Alaei A. Using preexposure prophylaxis, losing condoms? Preexposure prophylaxis promotion may undermine safe sex. AIDS. 2016;30(18):2753–6.CrossRefPubMed
51.
Zurück zum Zitat Cáceres CF, O'Reilly KR, Mayer KH, Baggaley R. PrEP implementation: moving from trials to policy and practice. Journal of the International AIDS Society. 2015;18(4Suppl 3):20222.PubMedPubMedCentral Cáceres CF, O'Reilly KR, Mayer KH, Baggaley R. PrEP implementation: moving from trials to policy and practice. Journal of the International AIDS Society. 2015;18(4Suppl 3):20222.PubMedPubMedCentral
53.
Zurück zum Zitat Kojima N, Davey DJ, Klausner JD. Pre-exposure prophylaxis for HIV infection and new sexually transmitted infections among men who have sex with men. AIDS. 2016;30(14):2251–2.CrossRefPubMed Kojima N, Davey DJ, Klausner JD. Pre-exposure prophylaxis for HIV infection and new sexually transmitted infections among men who have sex with men. AIDS. 2016;30(14):2251–2.CrossRefPubMed
54.
Zurück zum Zitat Scott HM, Klausner JD. Sexually transmitted infections and pre-exposure prophylaxis: challenges and opportunities among men who have sex with men in the US. AIDS Res Ther. 2016;13(1):5.CrossRefPubMedPubMedCentral Scott HM, Klausner JD. Sexually transmitted infections and pre-exposure prophylaxis: challenges and opportunities among men who have sex with men in the US. AIDS Res Ther. 2016;13(1):5.CrossRefPubMedPubMedCentral
55.
Zurück zum Zitat Harawa NT, Holloway IW, Leibowitz A, Weiss R, Gildner J, Landovitz RJ, et al. Serious concerns regarding a meta-analysis of preexposure prophylaxis use and STI acquisition. AIDS. 2017;31(5):739–40.CrossRefPubMedPubMedCentral Harawa NT, Holloway IW, Leibowitz A, Weiss R, Gildner J, Landovitz RJ, et al. Serious concerns regarding a meta-analysis of preexposure prophylaxis use and STI acquisition. AIDS. 2017;31(5):739–40.CrossRefPubMedPubMedCentral
56.
Zurück zum Zitat Schmidt MI, Duncan BB, Bang H, Pankow JS, Ballantyne CM, Golden SH, et al. Identifying individuals at high risk for diabetes. Diabetes Care. 2005;28(8):2013–8.CrossRefPubMed Schmidt MI, Duncan BB, Bang H, Pankow JS, Ballantyne CM, Golden SH, et al. Identifying individuals at high risk for diabetes. Diabetes Care. 2005;28(8):2013–8.CrossRefPubMed
57.
Zurück zum Zitat Pérez-Figueroa RE, Kapadia F, Barton SC, Eddy JA, Halkitis PN. Acceptability of PrEP uptake among racially/ethnically diverse young men who have sex with men: the P18 study. AIDS Educ Prev. 2015;27(2):112–25.CrossRefPubMedPubMedCentral Pérez-Figueroa RE, Kapadia F, Barton SC, Eddy JA, Halkitis PN. Acceptability of PrEP uptake among racially/ethnically diverse young men who have sex with men: the P18 study. AIDS Educ Prev. 2015;27(2):112–25.CrossRefPubMedPubMedCentral
58.
Zurück zum Zitat Calabrese SK, Earnshaw VA, Underhill K, Hansen NB, Dovidio JF. The impact of patient race on clinical decisions related to prescribing HIV pre-exposure prophylaxis (PrEP): assumptions about sexual risk compensation and implications for access. AIDS Behav. 2014;18(2):226–40.CrossRefPubMedPubMedCentral Calabrese SK, Earnshaw VA, Underhill K, Hansen NB, Dovidio JF. The impact of patient race on clinical decisions related to prescribing HIV pre-exposure prophylaxis (PrEP): assumptions about sexual risk compensation and implications for access. AIDS Behav. 2014;18(2):226–40.CrossRefPubMedPubMedCentral
59.
Zurück zum Zitat Bogart LM, Catz SL, Kelly JA, Benotsch EG. Factors influencing physicians’ judgments of adherence and treatment decisions for patients with HIV disease. Med Decis Mak. 2001;21(1):28–36.CrossRef Bogart LM, Catz SL, Kelly JA, Benotsch EG. Factors influencing physicians’ judgments of adherence and treatment decisions for patients with HIV disease. Med Decis Mak. 2001;21(1):28–36.CrossRef
60.
Zurück zum Zitat Stone VE. Physician contributions to disparities in HIV/AIDS care: the role of provider perceptions regarding adherence. Curr HIV/AIDS Rep. 2005;2:189–93.CrossRefPubMed Stone VE. Physician contributions to disparities in HIV/AIDS care: the role of provider perceptions regarding adherence. Curr HIV/AIDS Rep. 2005;2:189–93.CrossRefPubMed
61.
Zurück zum Zitat Malebranche DJ, Peterson JL, Fullilove RE, Stackhouse RW. Race and sexual identity: perceptions about medical culture and healthcare among black men who have sex with men. J Natl Med Assoc. 2004;96(1):97–107.PubMedPubMedCentral Malebranche DJ, Peterson JL, Fullilove RE, Stackhouse RW. Race and sexual identity: perceptions about medical culture and healthcare among black men who have sex with men. J Natl Med Assoc. 2004;96(1):97–107.PubMedPubMedCentral
62.
Zurück zum Zitat Valentine JA. Impact of attitudes and beliefs regarding African American sexual behavior on STD prevention and control in African American communities: unintended consequences. Sex Transm Dis. 2008;35(12):S23–9.CrossRefPubMed Valentine JA. Impact of attitudes and beliefs regarding African American sexual behavior on STD prevention and control in African American communities: unintended consequences. Sex Transm Dis. 2008;35(12):S23–9.CrossRefPubMed
63.
Zurück zum Zitat Grant RM, Koester KA. What people want from sex and preexposure prophylaxis. Curr Opin HIV AIDS. 2016;11(1):3–9.CrossRefPubMed Grant RM, Koester KA. What people want from sex and preexposure prophylaxis. Curr Opin HIV AIDS. 2016;11(1):3–9.CrossRefPubMed
65.
Zurück zum Zitat Blumberg SJ. Guarding against threatening HIV prevention messages: an information-processing model. Health Educ Behav. 2000;27(6):780–95.CrossRefPubMed Blumberg SJ. Guarding against threatening HIV prevention messages: an information-processing model. Health Educ Behav. 2000;27(6):780–95.CrossRefPubMed
67.
Zurück zum Zitat Hastings G, Stead M, Webb J. Fear appeals in social marketing: strategic and ethical reasons for concern. Psychol Mark. 2004;21(11):961–86.CrossRef Hastings G, Stead M, Webb J. Fear appeals in social marketing: strategic and ethical reasons for concern. Psychol Mark. 2004;21(11):961–86.CrossRef
68.
Zurück zum Zitat Golub SA, Operario D, Gorbach PM. Pre-exposure prophylaxis state of the science: empirical analogies for research and implementation. Curr HIV/AIDS Rep. 2010;7(4):201–9.CrossRefPubMedPubMedCentral Golub SA, Operario D, Gorbach PM. Pre-exposure prophylaxis state of the science: empirical analogies for research and implementation. Curr HIV/AIDS Rep. 2010;7(4):201–9.CrossRefPubMedPubMedCentral
69.
Zurück zum Zitat Smith DK, Van Handel M, Wolitski RJ, Stryker JE, Hall HI, Prejean J, et al. Vital signs: estimated percentages and numbers of adults with indications for preexposure prophylaxis to prevent HIV acquisition—United States, 2015. MMWR Morb Mortal Wkly Rep. 2015;64(46):1291–5.CrossRefPubMed Smith DK, Van Handel M, Wolitski RJ, Stryker JE, Hall HI, Prejean J, et al. Vital signs: estimated percentages and numbers of adults with indications for preexposure prophylaxis to prevent HIV acquisition—United States, 2015. MMWR Morb Mortal Wkly Rep. 2015;64(46):1291–5.CrossRefPubMed
70.
Zurück zum Zitat American College of Obstetricians and Gynecologists. Reproductive life planning to reduce unintended pregnancy. Committee Opinion No. 654. Obstet Gynecol. 2016;127:e66–9.CrossRef American College of Obstetricians and Gynecologists. Reproductive life planning to reduce unintended pregnancy. Committee Opinion No. 654. Obstet Gynecol. 2016;127:e66–9.CrossRef
Metadaten
Titel
PrEP Stigma: Implicit and Explicit Drivers of Disparity
verfasst von
Sarit A. Golub
Publikationsdatum
19.02.2018
Verlag
Springer US
Erschienen in
Current HIV/AIDS Reports / Ausgabe 2/2018
Print ISSN: 1548-3568
Elektronische ISSN: 1548-3576
DOI
https://doi.org/10.1007/s11904-018-0385-0

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