Prescribing pattern of antidiabetic drugs and achievement of glycemic control in T2DM patients tertiary care hospital in North India

Study was undertaken to identify patterns of antidiabetic drugs prescribing in established type 2 diabetes mellitus. Patients with established T2DM who attended the endocrinology Outpatient Clinic in Postgraduate Institute of Medical Education and Research, Chandigarh, India were evaluated for social, demographical and clinical variables and medications. 1185 established T2DM patients were assessed. Metformin was the most commonly prescribed drug [827 (70 %)], followed by insulin [627 (53 %)], sulfonylureas [520 (44 %)], and pioglitazone [329 (28 %)]. The most frequently prescribed monotherapy was insulin [214 (62 %)], followed by metformin in 81 (23 %), sulfonylurea in 49 (14 %) and pioglitazone in 4 (1 %) patients. 704 (59 %) treated patients had uncontrolled hyperglycemia. Family history (OR 1.76, 95%CI 1.18, 2.64), diabetes duration (OR 2.62, 95 % CI 2.05, 3.36), HbA1c (OR 1.25, 95%CI 1.01, 1.50), neuropathy(OR 1.57, 95 % CI, 1.14, 2.2), nephropathy(OR 1.77, 95 % CI 1.40, 2.24), retinopathy (OR 1.97, 95 % CI 1.63, 2.40), coronary arterial disease (CAD) (OR 1.57, 95 % CI, 1.14, 2.2) and diabetic foot (OR 1.62, 95 % CI 1.12, 2.40) were all significantly associated with insulin therapy. Obese and overweight patients were prescribed oral antidiabetic drugs. Medication use was consistent with practice guidelines in T2DM, even though the outcome did not reach the goal.