Erschienen in:
01.01.2012 | Materno-Fetal Medicine
Presence of HPV DNA in placenta and cervix of pregnant Mexican women
verfasst von:
Oscar Uribarren-Berrueta, José Sánchez-Corona, Héctor Montoya-Fuentes, Benjamin Trujillo-Hernández, Clemente Vásquez
Erschienen in:
Archives of Gynecology and Obstetrics
|
Ausgabe 1/2012
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Abstract
Purpose
To identify the presence of HPV DNA in cervical as well as in placental tissue of pregnant Mexican women and to determine which type is more frequent.
Methods
In a cross-sectional study, 56 placental samples were obtained from 72 pregnant women. HPV DNA was extracted and amplified with polymerase chain reaction using a consensus primer and then identified by type using RsaI endonuclease. The main outcome measures were placenta with/without HPV relation and HPV types in placenta.
Results
HPV DNA was identified in 75% of cervical tissue samples and 47.2% of placental tissue samples. Type 18 was the most frequently identified HPV type.
Conclusions
There was a higher frequency of HPV DNA found in the cervix of Mexican women during pregnancy than reported in the previous studies. Its identification in full-term placental tissue has no relation to the type of delivery in childbirth.