Pneumoconiosis may play an important role in the development of chronic obstructive pulmonary disease (COPD), and the complication of COPD may impose a heavy burden of illness.
The study was conducted in Hunan Province in China from December 1, 2015, to December 1, 2016. Consecutive underground male pneumoconiosis patients employed for at least 1 year were recruited from the Hunan Occupational Disease Prevention Institute. Patient information, respiratory symptoms and clinical data were collected using a structured questionnaire. The diagnosis of COPD were assessed using the Global Initiative for Chronic Obstructive Lung Disease (GOLD) criteria. Logistic regression analyses were conducted to examine the clinical and demographic risk factors of COPD among pneumoconiosis patients.
The prevalence of COPD in our sample of pneumoconiosis patients was 18.65% (119/638). In pneumoconiosis patients with and without smoking history, the prevalence of COPD was 19.32 and 16.77%. Compared with non-COPD patients, those with COPD are older in age, have longer exposure time, have lower body mass index (BMI), have a higher smoking index and have worse pulmonary function (all p < 0.05). For the five respiratory symptoms (cough, sputum, wheeze, dyspnea, and chest tightness), only the presence of wheeze and the severity scores for wheeze or dyspnea showed significant differences between the COPD and non-COPD groups (p < 0.01). Multivariate logistic regression analysis revealed that advanced pneumoconiosis category, older age and the presence of wheeze symptoms were significant risk factors for the development of COPD among pneumoconiosis patients.
Pneumoconiosis patients are at a high risk of COPD, and pneumoconiosis patients with COPD may suffer more severe respiratory symptoms, such as wheeze and dyspnea, than patients without COPD. Advanced pneumoconiosis category, older age and the presence of wheeze symptoms are associated with an increased risk of COPD in pneumoconiosis. We proposed that a routine assessment of lung function is necessary for timely and adequate clinical management.
Cohen RAC. Is the increasing prevalence and severity of coal workers pneumoconiosis in the United States due to increasing silica exposure? J Occup Environ Med. 2010;67(10):649–50. CrossRef
Weston A. Work-related lung diseases. IARC Sci Publ. 2011;163:387–405.
Ministry of Health of China. National occupational diseases report for 2013. (2014). Availableat: http://www.nhfpc.gov.cn/jkj/s5899t/201406/ed8ed220d0b74010bcb6dcd8e340f4fb.shtml. Accessed June 2014.
Eisner MD, Anthonisen N, Coultas D, et al. An official American Thoracic Society public policy statement: novel risk factors and the global burden of chronic obstructive pulmonary disease. Am J Resp Crit Care. 2010;182(5):693–718. CrossRef
Ornek T, Atalay F, Erboy F, et al. Is pneumoconiosis a factor of severity in acute exacerbation of chronic obstructive pulmonary disease[J]. Clin Ter. 2013;164(6):e473–7. PubMed
Xia Y, Liu J, Shi T, et al. Prevalence of pneumoconiosis in Hubei, China from 2008 to 2013. Inter J Env Res Pub Heal. 2014;11(9):8612–21. CrossRef
ILO. Guidelines for the use of ILO International classification of radiographs of pneumoconiosis. Geneva: International Labour Office 2002 (Occupational Safety and Health Series, No 22 (rev 2000); 2000.
Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease updated 2015. ( http://goldcopd.org/).
Zhou M. A subnational analysis for mortality and prevalence of chronic obstructive pulmonary disease in China 1990-2013: findings from global burden of disease study (GBD) 2013[J]. 2016.
Sadhra S, Kurmi OP, Sadhra SS, et al. Occupational COPD and job exposure matrices: a systematic review and meta-analysis. Int J Chronic Obstr. 2017;12:725. CrossRef
Altnsoy B, Öz İİ, Erboy F, et al. Emphysema and Airflow Obstruction in Non-Smoking Coal Miners with Pneumoconiosis. Med Sci Monit. 2016;22:4887. CrossRef
Kuempel ED, Wheeler MW, Smith RJ, et al. Contributions of dust exposure and cigarette smoking to emphysema severity in coal miners in the United States. Am J Resp Crit Care. 2009;180(3):257–64. CrossRef
Nishimura K, Mitsuma S, Kobayashi A, et al. COPD and disease-specific health status in a working population. Resp Res. 2013;14(1):61. CrossRef
De Zotti R. Chronic obstructive pulmonary disease (COPD) and occupational exposure to mineral dust. G Ital Med Lav Ergon. 2002;24(2):144–6. PubMed
- Prevalence and characteristics of COPD among pneumoconiosis patients at an occupational disease prevention institute: a cross-sectional study
- BioMed Central
Neu im Fachgebiet Innere Medizin
Meistgelesene Bücher aus der Inneren Medizin
Mail Icon II