The online version of this article (doi:10.1186/1471-2261-14-136) contains supplementary material, which is available to authorized users.
The authors declare that they have no competing interests.
HL: first author of this work, has made substantial contributions to the conception and design of the paper and the analysis and interpretation of data, and been involved in drafting the manuscript. FP, LYS, JZC, XYZ, CNZ, JBL have participated in patient evaluations, data collection, and report writing. KS: was involved in statistical analysis. CSX has made contributions to the conception and design of the paper, and been involved in revising the manuscript. RTH: was involved in supervisory role in study concept, manuscript writing and critical review of the work at all stages. All authors read and approved the final manuscript.
The various prevalence of LVH and abnormal LV geometry have been reported in different populations. So far, only a few reports are available on the prevalence of LV geometric patterns in a large Chinese untreated hypertensive population.
A total of 9,286 subjects (5167 men and 4119 women) completed the survey and 1641 untreated hypertensive patients (1044 males and 597 females) enrolled in the present study. The LV geometry was classified into four patterns: normal; abnormal,defined as concentric remodeling;concentric or eccentric hypertrophy based on the values of left ventricular mass index (LVMI) and relative wall thickness (RWT). Logistic regression model was applied to determine the odds ratio (OR) and 95% confidence intervals (CI) of the risk factors of left ventricular hypertrophy.
The prevalence of LVH was 20.2% in untreated hypertensive patients, much higher in women (30.8%) than in men (14.2%) (P < 0.01). The prevalence of LV geometrical patterns was 34.9%, 11.1%, 9.1% for concentric remodeling, concentric and eccentric hypertrophy,respectively. After adjustment by using Logistic regression model, the risk factors for LVH and abnormal LV geometry were age, female, systolic blood pressure, and body mass index. And low high density lipoprotein maybe a positive factor.
The prevalence of LVH and abnormal LV geometric patterns was higher in women than in men and increased with age. It is crucial to improve the awareness rate of hypertension and control the risk factors of CV complications in untreated hypertensive population.
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- Prevalence and risk factors of abnormal left ventricular geometrical patterns in untreated hypertensive patients
- BioMed Central
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