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2017 | Prostatakarzinom | OriginalPaper | Buchkapitel Zur Zeit gratis

3. Primärdiagnostik

verfasst von : Dr. med. Anja Weidner, Dr. med. Ali Abaci, Ingrid, cand. med. Natalie Donk, Prof. Dr. med. Ulrike Attenberger

Erschienen in: MR- und PET-Bildgebung der Prostata

Verlag: Springer Berlin Heidelberg

Zusammenfassung

Die Magnetresonanztomografie ist bei der Beurteilung der Transitionalzone und der anterioren Anteile der Prostata dem Ultraschall überlegen. Weitere Vorteile sind deren Standardisierbarkeit und Untersucherunabhängigkeit. Ergänzend zu den anatomischen T2-gewichteten werden funktionelle Sequenzen zur Differenzierung benigner und maligner Läsionen durchgeführt. Eine Magnetresonanztomografie ist in erster Linie bei Patienten mit bereits stattgehabter negativer Biopsie und weiterhin bestehendem Tumorverdacht sowie zur Therapieplanung aggressiver Tumoren mit hohem Gleason Score oder in lokal fortgeschrittenem Stadium indiziert. Für die Untersuchung der Prostata ist der Ultraschall die wichtigste bildgebende Modalität. Die transrektale Sonografie dient sowohl diagnostischen als auch therapeutischen Zwecken und kann sowohl gut- als auch bösartige Veränderungen beurteilen und das therapeutische Vorgehen planen. In der Diagnostik des Prostatakarzinoms besitzt die transrektale Sonografie eine hohe Sensitivität bei eingeschränkter Spezifität.
Literatur
Zurück zum Zitat Akin O et al (2006) Transition zone prostate cancers: features, detection, localization, and Staging at endorectal MR imaging. Radiology 239(3):784–792 Akin O et al (2006) Transition zone prostate cancers: features, detection, localization, and Staging at endorectal MR imaging. Radiology 239(3):784–792
Zurück zum Zitat Albertsen PC et al (1998) Competing risk analysis of men aged 55 to 74 years at diagnosis managed conservatively for clinically localized prostate cancer. JAMA 280(11):975–980 Albertsen PC et al (1998) Competing risk analysis of men aged 55 to 74 years at diagnosis managed conservatively for clinically localized prostate cancer. JAMA 280(11):975–980
Zurück zum Zitat Anderson A et al (2000) Effects of cell volume fraction changes on apparent diffusion in human cells. Magnetic resonance imaging 18(6):689–695 Anderson A et al (2000) Effects of cell volume fraction changes on apparent diffusion in human cells. Magnetic resonance imaging 18(6):689–695
Zurück zum Zitat Asbach PM, Haas M, Hamm B (2015) MR imaging of the prostate. Radiologe 55(12):1088–1096 Asbach PM, Haas M, Hamm B (2015) MR imaging of the prostate. Radiologe 55(12):1088–1096
Zurück zum Zitat Attenberger U, Morelli SS, Haecker A, Weidner A, Weiss C, Hausmann D, Dinter DJ, Sertdemir M (2016) Is there a role for functional MR techniques such as diffusion-weighted and perfusion imaging for the assessment of extracapsular extension in prostate cancer? – A preliminary analysis with histopathologic correlation. In preparation. Attenberger U, Morelli SS, Haecker A, Weidner A, Weiss C, Hausmann D, Dinter DJ, Sertdemir M (2016) Is there a role for functional MR techniques such as diffusion-weighted and perfusion imaging for the assessment of extracapsular extension in prostate cancer? – A preliminary analysis with histopathologic correlation. In preparation.
Zurück zum Zitat Attenberger U et al (2015) Small Field-of-view single-shot EPI-DWI of the prostate: Evaluation of spatially-tailored two-dimensional radiofrequency excitation pulses. Z Med Phys 20:S0939-3889(15)00094-X Attenberger U et al (2015) Small Field-of-view single-shot EPI-DWI of the prostate: Evaluation of spatially-tailored two-dimensional radiofrequency excitation pulses. Z Med Phys 20:S0939-3889(15)00094-X
Zurück zum Zitat Barentsz JO et al (2012) ESUR prostate MR guidelines 2012. European radiology 22(4):746–757 Barentsz JO et al (2012) ESUR prostate MR guidelines 2012. European radiology 22(4):746–757
Zurück zum Zitat Bezzi M et al (1988) Prostatic carcinoma: staging with MR imaging at 1.5 T. Radiology 169(2):339–346 Bezzi M et al (1988) Prostatic carcinoma: staging with MR imaging at 1.5 T. Radiology 169(2):339–346
Zurück zum Zitat Bittencourt LK et al (2012) Prostate MRI: diffusion-weighted imaging at 1.5T correlates better with prostatectomy Gleason Grades than TRUS-guided biopsies in peripheral zone tumours. Eur Radiol 22(2):468–475 Bittencourt LK et al (2012) Prostate MRI: diffusion-weighted imaging at 1.5T correlates better with prostatectomy Gleason Grades than TRUS-guided biopsies in peripheral zone tumours. Eur Radiol 22(2):468–475
Zurück zum Zitat Bjurlin MA et al (2013) Optimization of initial prostate biopsy in clinical practice: sampling, labeling and specimen processing. J Urol 189(6):2039–2046 Bjurlin MA et al (2013) Optimization of initial prostate biopsy in clinical practice: sampling, labeling and specimen processing. J Urol 189(6):2039–2046
Zurück zum Zitat Blackledge MD et al (2011) Computed diffusion-weighted MR imaging may improve tumor detection. Radiology 261(2):573–581 Blackledge MD et al (2011) Computed diffusion-weighted MR imaging may improve tumor detection. Radiology 261(2):573–581
Zurück zum Zitat Bloch BN et al (2007) Prostate cancer: accurate determination of extracapsular extension with high-spatial-resolution dynamic contrast-enhanced and T2-weighted MR imaging – initial results. Radiology 245(1):176–185 Bloch BN et al (2007) Prostate cancer: accurate determination of extracapsular extension with high-spatial-resolution dynamic contrast-enhanced and T2-weighted MR imaging – initial results. Radiology 245(1):176–185
Zurück zum Zitat Bonekamp D et al (2011) Advancements in MR imaging of the prostate: From diagnosis to interventions. Radiographics 31(3):677 Bonekamp D et al (2011) Advancements in MR imaging of the prostate: From diagnosis to interventions. Radiographics 31(3):677
Zurück zum Zitat Cornfeld DM, Weinreb JC (2007) MR imaging of the prostate: 1.5T versus 3T. Magnetic resonance imaging clinics of North America 15(3):433–448, viii Cornfeld DM, Weinreb JC (2007) MR imaging of the prostate: 1.5T versus 3T. Magnetic resonance imaging clinics of North America 15(3):433–448, viii
Zurück zum Zitat De Rooij M et al (2014) Accuracy of multiparametric MRI for prostate cancer detection: a meta-analysis. AJR Am J Roentgenol 202(2):343–351 De Rooij M et al (2014) Accuracy of multiparametric MRI for prostate cancer detection: a meta-analysis. AJR Am J Roentgenol 202(2):343–351
Zurück zum Zitat De Souza NM et al (2007) Magnetic resonance imaging in prostate cancer: the value of apparent diffusion coefficients for identifying malignant nodules. British J Radiology 80(950):90–95 De Souza NM et al (2007) Magnetic resonance imaging in prostate cancer: the value of apparent diffusion coefficients for identifying malignant nodules. British J Radiology 80(950):90–95
Zurück zum Zitat Fortuin A et al (2013) Molecular and functional imaging for detection of lymph node metastases in prostate cancer. Int J Mol Sci 14(7):13842–13875 Fortuin A et al (2013) Molecular and functional imaging for detection of lymph node metastases in prostate cancer. Int J Mol Sci 14(7):13842–13875
Zurück zum Zitat Fütterer JJ et al (2006) Prostate cancer localization with dynamic contrast-enhanced MR imaging and proton MR spectroscopic imaging. Radiology 241(2):449–458 Fütterer JJ et al (2006) Prostate cancer localization with dynamic contrast-enhanced MR imaging and proton MR spectroscopic imaging. Radiology 241(2):449–458
Zurück zum Zitat Fütterer JJ et al (2005) Staging prostate cancer with dynamic contrast-enhanced endorectal MR imaging prior to radical prostatectomy: Experienced versus Less experienced readers. Radiology 237(2):541 Fütterer JJ et al (2005) Staging prostate cancer with dynamic contrast-enhanced endorectal MR imaging prior to radical prostatectomy: Experienced versus Less experienced readers. Radiology 237(2):541
Zurück zum Zitat Gupta RT et al (2015) Apparent diffusion coefficient values of the benign central zone of the prostate: Comparison with low- and high-grade prostate cancer. AJR Am J Roentgenol 205(2):331–336 Gupta RT et al (2015) Apparent diffusion coefficient values of the benign central zone of the prostate: Comparison with low- and high-grade prostate cancer. AJR Am J Roentgenol 205(2):331–336
Zurück zum Zitat Haider MA et al (2007) Combined T2-weighted and diffusion-weighted MRI for localization of prostate cancer. AJR 189(2):323–328 Haider MA et al (2007) Combined T2-weighted and diffusion-weighted MRI for localization of prostate cancer. AJR 189(2):323–328
Zurück zum Zitat Hallscheidt P, Haverkamp A (2011) Urogenitale Bildgebung. Springer-Verlag Berlin Heidelberg New York Hallscheidt P, Haverkamp A (2011) Urogenitale Bildgebung. Springer-Verlag Berlin Heidelberg New York
Zurück zum Zitat Hambrock T et al (2008) Thirty-two-channel coil 3T magnetic resonance-guided biopsies of prostate tumor suspicious regions identified on multimodality 3T magnetic resonance imaging: technique and feasibility. Invest Radiol 43(10):686–694 Hambrock T et al (2008) Thirty-two-channel coil 3T magnetic resonance-guided biopsies of prostate tumor suspicious regions identified on multimodality 3T magnetic resonance imaging: technique and feasibility. Invest Radiol 43(10):686–694
Zurück zum Zitat Hausmann D et al (2012) Apparent diffusion coefficient and sodium concentration measurements in human prostate tissue via hydrogen-1 and sodium-23 magnetic resonance imaging in a clinical setting at 3T. Invest Radiol 47(12):677–682 Hausmann D et al (2012) Apparent diffusion coefficient and sodium concentration measurements in human prostate tissue via hydrogen-1 and sodium-23 magnetic resonance imaging in a clinical setting at 3T. Invest Radiol 47(12):677–682
Zurück zum Zitat Hautmann R, Gschwend JE (2014) Urologie. Springer-Verlag Berlin Heidelberg New York Hautmann R, Gschwend JE (2014) Urologie. Springer-Verlag Berlin Heidelberg New York
Zurück zum Zitat Heidenreich A et al (2011) EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and treatment of clinically localised disease. European urology, 2011. 59(1):61–71 Heidenreich A et al (2011) EAU guidelines on prostate cancer. Part 1: screening, diagnosis, and treatment of clinically localised disease. European urology, 2011. 59(1):61–71
Zurück zum Zitat Heerschap A et al (1997) Proton MR spectroscopy of the normal human prostate with an endorectal coil and a double spin echo pulse sequence. Magnetic resonance in medicine 37(2):204–213 Heerschap A et al (1997) Proton MR spectroscopy of the normal human prostate with an endorectal coil and a double spin echo pulse sequence. Magnetic resonance in medicine 37(2):204–213
Zurück zum Zitat Hofmann R, Hegele A, Honacker A (2012) Ultraschall in der Urologie. Springer-Verlag Berlin Heidelberg New York Hofmann R, Hegele A, Honacker A (2012) Ultraschall in der Urologie. Springer-Verlag Berlin Heidelberg New York
Zurück zum Zitat Hoskin PJ et al (2007) Hypoxia in prostate cancer: correlation of BOLD-MRI with Pimonidazole immunohistochemistry – initial observations. International J Radiation Oncology* Biology* Physics 68(4):1065–1071 Hoskin PJ et al (2007) Hypoxia in prostate cancer: correlation of BOLD-MRI with Pimonidazole immunohistochemistry – initial observations. International J Radiation Oncology* Biology* Physics 68(4):1065–1071
Zurück zum Zitat Hovels AM et al (2008) The diagnostic accuracy of CT and MRI in the staging of pelvic lymph nodes in patients with prostate cancer: a meta-analysis. Clin Radiol 63(4):387–395 Hovels AM et al (2008) The diagnostic accuracy of CT and MRI in the staging of pelvic lymph nodes in patients with prostate cancer: a meta-analysis. Clin Radiol 63(4):387–395
Zurück zum Zitat Hricak H et al (2007) Imaging prostate cancer: A multidisciplinary perspective. Radiology 243(1):28 Hricak H et al (2007) Imaging prostate cancer: A multidisciplinary perspective. Radiology 243(1):28
Zurück zum Zitat Hricak H et al (1987) MR imaging of the prostate gland: normal anatomy. AJR Am J Roentgenol 148(1):51–58 Hricak H et al (1987) MR imaging of the prostate gland: normal anatomy. AJR Am J Roentgenol 148(1):51–58
Zurück zum Zitat Je M (1981) The zonal anatomy of the prostate. The Prostate 2:35–49 Je M (1981) The zonal anatomy of the prostate. The Prostate 2:35–49
Zurück zum Zitat Jie C, Rongbo L, Ping (2014) The value of diffusion-weighted imaging in the detection of prostate cancer: a meta-analysis. Eur Radiol 24(8):1929–1941 Jie C, Rongbo L, Ping (2014) The value of diffusion-weighted imaging in the detection of prostate cancer: a meta-analysis. Eur Radiol 24(8):1929–1941
Zurück zum Zitat Kim CK, Park BK, Kim B (2010) High-b-value diffusion-weighted imaging at 3 T to detect prostate cancer: comparisons between b values of 1,000 and 2,000 s/mm2. AJR Am J Roentgenol 194(1):W33–37 Kim CK, Park BK, Kim B (2010) High-b-value diffusion-weighted imaging at 3 T to detect prostate cancer: comparisons between b values of 1,000 and 2,000 s/mm2. AJR Am J Roentgenol 194(1):W33–37
Zurück zum Zitat Kim JH et al (2008) Apparent diffusion coefficient: prostate cancer versus noncancerous tissue according to anatomical region. J Magnetic Resonance Imaging 28(5):1173–1179 Kim JH et al (2008) Apparent diffusion coefficient: prostate cancer versus noncancerous tissue according to anatomical region. J Magnetic Resonance Imaging 28(5):1173–1179
Zurück zum Zitat Kurhanewicz J et al (1991) 31P spectroscopy of the human prostate gland in vivo using a transrectal probe. Magnetic resonance in medicine 22(2):404–413 Kurhanewicz J et al (1991) 31P spectroscopy of the human prostate gland in vivo using a transrectal probe. Magnetic resonance in medicine 22(2):404–413
Zurück zum Zitat Li Y et al (2013) Diagnostic performance of contrast enhanced ultrasound in patients with prostate cancer: a meta-analysis. Acad Radiol 20(2):156–164 Li Y et al (2013) Diagnostic performance of contrast enhanced ultrasound in patients with prostate cancer: a meta-analysis. Acad Radiol 20(2):156–164
Zurück zum Zitat Liu X et al (2013) Differentiation of central gland prostate cancer from benign prostatic hyperplasia using monoexponential and biexponential diffusion-weighted imaging. Magn Reson Imaging 31(8):1318–1324 Liu X et al (2013) Differentiation of central gland prostate cancer from benign prostatic hyperplasia using monoexponential and biexponential diffusion-weighted imaging. Magn Reson Imaging 31(8):1318–1324
Zurück zum Zitat Loch T et al (2004) Transrectal ultrasound guided biopsy of the prostate: random sextant versus biopsies of sono-morphologically suspicious lesions. World J Urol 22(5):357–360 Loch T et al (2004) Transrectal ultrasound guided biopsy of the prostate: random sextant versus biopsies of sono-morphologically suspicious lesions. World J Urol 22(5):357–360
Zurück zum Zitat Luboldt W et al (2008) Prostate carcinoma: diffusion-weighted imaging as potential alternative to conventional MR and 11C-choline PET/CT for detection of bone metastases. Radiology 249(3):1017–1025 Luboldt W et al (2008) Prostate carcinoma: diffusion-weighted imaging as potential alternative to conventional MR and 11C-choline PET/CT for detection of bone metastases. Radiology 249(3):1017–1025
Zurück zum Zitat Mazaheri Y et al (2009) Prostate tumor volume measurement with combined T2-weighted imaging and diffusion-weighted MR: correlation with pathologic tumor volume. Radiology 252(2):449–457 Mazaheri Y et al (2009) Prostate tumor volume measurement with combined T2-weighted imaging and diffusion-weighted MR: correlation with pathologic tumor volume. Radiology 252(2):449–457
Zurück zum Zitat Near J, Bartha R (2010) Quantitative sodium MRI of the mouse prostate. Magnetic resonance in medicine 63(3):822–827 Near J, Bartha R (2010) Quantitative sodium MRI of the mouse prostate. Magnetic resonance in medicine 63(3):822–827
Zurück zum Zitat Orczyk C et al (2016) A prospective comparative analysis of the accuracy of HistoScanning and multiparametric magnetic resonance imaging in the localization of prostate cancer among men undergoing radical prostatectomy. Urol Oncol 34(1):3 e1–8 Orczyk C et al (2016) A prospective comparative analysis of the accuracy of HistoScanning and multiparametric magnetic resonance imaging in the localization of prostate cancer among men undergoing radical prostatectomy. Urol Oncol 34(1):3 e1–8
Zurück zum Zitat Outwater EK et al (1994) Prostate carcinoma: assessment of diagnostic criteria for capsular penetration on endorectal coil MR images. Radiology 193(2):333 Outwater EK et al (1994) Prostate carcinoma: assessment of diagnostic criteria for capsular penetration on endorectal coil MR images. Radiology 193(2):333
Zurück zum Zitat Padhani AR, Harvey CJ, Cosgrove DO (2005) Angiogenesis imaging in the management of prostate cancer. Nature Clinical Practice Urology 2(12):596–607 Padhani AR, Harvey CJ, Cosgrove DO (2005) Angiogenesis imaging in the management of prostate cancer. Nature Clinical Practice Urology 2(12):596–607
Zurück zum Zitat Pelzer AE et al (2013) Real-time sonoelastography compared to magnetic resonance imaging using four different modalities at 3.0 T in the detection of prostate cancer: strength and weaknesses. Eur J Radiol 82(5):814–821 Pelzer AE et al (2013) Real-time sonoelastography compared to magnetic resonance imaging using four different modalities at 3.0 T in the detection of prostate cancer: strength and weaknesses. Eur J Radiol 82(5):814–821
Zurück zum Zitat Podo F (1999) Tumour phospholipid metabolism. NMR in Biomedicine 12(7):413–439 Podo F (1999) Tumour phospholipid metabolism. NMR in Biomedicine 12(7):413–439
Zurück zum Zitat Postema A et al (2015) Ultrasound modalities and quantification: developments of multiparametric ultrasonography, a new modality to detect, localize and target prostatic tumors. Curr Opin Urol 25(3):191–197 Postema A et al (2015) Ultrasound modalities and quantification: developments of multiparametric ultrasonography, a new modality to detect, localize and target prostatic tumors. Curr Opin Urol 25(3):191–197
Zurück zum Zitat Qayyum A et al (2004) Organ-confined prostate cancer: effect of prior transrectal biopsy on endorectal MRI and MR spectroscopic imaging. AJR Am J Roentgenol 183(4):1079–1083 Qayyum A et al (2004) Organ-confined prostate cancer: effect of prior transrectal biopsy on endorectal MRI and MR spectroscopic imaging. AJR Am J Roentgenol 183(4):1079–1083
Zurück zum Zitat Ren J et al (2009) Seminal vesicle invasion in prostate cancer: prediction with combined T2-weighted and diffusion-weighted MR imaging. European radiology 19(10):2481–2486 Ren J et al (2009) Seminal vesicle invasion in prostate cancer: prediction with combined T2-weighted and diffusion-weighted MR imaging. European radiology 19(10):2481–2486
Zurück zum Zitat Ren J et al (2008) Diffusion-weighted imaging in normal prostate and differential diagnosis of prostate diseases. Abdominal imaging 33(6):724–728 Ren J et al (2008) Diffusion-weighted imaging in normal prostate and differential diagnosis of prostate diseases. Abdominal imaging 33(6):724–728
Zurück zum Zitat Roethke M et al (2014) Seminal vesicle invasion: accuracy and analysis of infiltration patterns with high-spatial resolution T2-weighted sequences on endorectal magnetic resonance imaging. Urol Int 92(3):294–249 Roethke M et al (2014) Seminal vesicle invasion: accuracy and analysis of infiltration patterns with high-spatial resolution T2-weighted sequences on endorectal magnetic resonance imaging. Urol Int 92(3):294–249
Zurück zum Zitat Roethke M et al (2013) [PI-RADS classification: structured reporting for MRI of the prostate]. Rofo 185(3):253–261 Roethke M et al (2013) [PI-RADS classification: structured reporting for MRI of the prostate]. Rofo 185(3):253–261
Zurück zum Zitat Rübben H (2014) Uroonkologie. Springer-Verlag Berlin Heidelberg New York Rübben H (2014) Uroonkologie. Springer-Verlag Berlin Heidelberg New York
Zurück zum Zitat Sala E et al (2006) Endorectal MR Imaging in the Evaluation of Seminal Vesicle Invasion: Diagnostic Accuracy and Multivariate Feature Analysis. Radiology 238(3):929 Sala E et al (2006) Endorectal MR Imaging in the Evaluation of Seminal Vesicle Invasion: Diagnostic Accuracy and Multivariate Feature Analysis. Radiology 238(3):929
Zurück zum Zitat Sato C et al (2005) Differentiation of noncancerous tissue and cancer lesions by apparent diffusion coefficient values in transition and peripheral zones of the prostate. J Magnetic Resonance Imaging 21(3):258–262 Sato C et al (2005) Differentiation of noncancerous tissue and cancer lesions by apparent diffusion coefficient values in transition and peripheral zones of the prostate. J Magnetic Resonance Imaging 21(3):258–262
Zurück zum Zitat Schiebler TH, Korf HW (2007) Anatomie. Steinkopff-Verlag Darmstadt Schiebler TH, Korf HW (2007) Anatomie. Steinkopff-Verlag Darmstadt
Zurück zum Zitat Schiffmann J et al (2015) Controversial evidence for the use of HistoScanning in the detection of prostate cancer. World J Urol 33(12):1993–1999 Schiffmann J et al (2015) Controversial evidence for the use of HistoScanning in the detection of prostate cancer. World J Urol 33(12):1993–1999
Zurück zum Zitat Shi H, Ding HY (2007) Diffusion weighted imaging: its diagnostic and differential value for prostate cancer. Zhonghua Nan Ke Xue 13(7):605–609 Shi H, Ding HY (2007) Diffusion weighted imaging: its diagnostic and differential value for prostate cancer. Zhonghua Nan Ke Xue 13(7):605–609
Zurück zum Zitat Sourbron S et al (2004) Deconvolution of dynamic contrast-enhanced MRI data by linear inversion: choice of the regularization parameter. Magn Reson Med 52(1):209–213 Sourbron S et al (2004) Deconvolution of dynamic contrast-enhanced MRI data by linear inversion: choice of the regularization parameter. Magn Reson Med 52(1):209–213
Zurück zum Zitat Tan CH et al (2015) Dynamic contrast-enhanced MRI for the detection of prostate cancer: meta-analysis. AJR Am J Roentgenol 204(4):W439–448 Tan CH et al (2015) Dynamic contrast-enhanced MRI for the detection of prostate cancer: meta-analysis. AJR Am J Roentgenol 204(4):W439–448
Zurück zum Zitat Tan CH, Wang J, Kundra V (2010) Diffusion weighted imaging in prostate cancer. European radiology 1–11 Tan CH, Wang J, Kundra V (2010) Diffusion weighted imaging in prostate cancer. European radiology 1–11
Zurück zum Zitat Turkbey B et al (2011) Multiparametric 3T prostate magnetic resonance imaging to detect cancer: histopathological correlation using prostatectomy specimens processed in customized magnetic resonance imaging based molds. The J urology 186(5):1818–1824 Turkbey B et al (2011) Multiparametric 3T prostate magnetic resonance imaging to detect cancer: histopathological correlation using prostatectomy specimens processed in customized magnetic resonance imaging based molds. The J urology 186(5):1818–1824
Zurück zum Zitat Turkbey B et al (2010) Prostate cancer: value of multiparametric MR imaging at 3 T for detection – histopathologic correlation. Radiology 255(1):89–99 Turkbey B et al (2010) Prostate cancer: value of multiparametric MR imaging at 3 T for detection – histopathologic correlation. Radiology 255(1):89–99
Zurück zum Zitat Van Hove A et al (2014) Comparison of image-guided targeted biopsies versus systematic randomized biopsies in the detection of prostate cancer: a systematic literature review of well-designed studies. World J Urol 32(4):847–858 Van Hove A et al (2014) Comparison of image-guided targeted biopsies versus systematic randomized biopsies in the detection of prostate cancer: a systematic literature review of well-designed studies. World J Urol 32(4):847–858
Zurück zum Zitat Wang X et al (2014) High-b-value diffusion-weighted MRI for the detection of prostate cancer at 3 T. Clin Radiol 69(11):1165–1170 Wang X et al (2014) High-b-value diffusion-weighted MRI for the detection of prostate cancer at 3 T. Clin Radiol 69(11):1165–1170
Zurück zum Zitat Weinreb JC et al (2016) PI-RADS prostate imaging – Reporting and data system: 2015, version 2. Eur Urol 69(1):16–40 Weinreb JC et al (2016) PI-RADS prostate imaging – Reporting and data system: 2015, version 2. Eur Urol 69(1):16–40
Zurück zum Zitat Weinreb JC et al (2009) Prostate cancer: sextant localization at MR imaging and MR spectroscopic imaging before prostatectomy – results of ACRIN prospective multi-institutional clinicopathologic study. Radiology 251(1):122 Weinreb JC et al (2009) Prostate cancer: sextant localization at MR imaging and MR spectroscopic imaging before prostatectomy – results of ACRIN prospective multi-institutional clinicopathologic study. Radiology 251(1):122
Zurück zum Zitat Wetter A et al (2015) High and ultra-high b-value diffusion-weighted imaging in prostate cancer: a quantitative analysis. Acta Radiol 56(8):1009–1015 Wetter A et al (2015) High and ultra-high b-value diffusion-weighted imaging in prostate cancer: a quantitative analysis. Acta Radiol 56(8):1009–1015
Zurück zum Zitat Xylinas E et al (2011) Role of pelvic phased array magnetic resonance imaging in staging of prostate cancer specifically in patients diagnosed with clinically locally advanced tumours by digital rectal examination. World J urology:31:881–886 Xylinas E et al (2011) Role of pelvic phased array magnetic resonance imaging in staging of prostate cancer specifically in patients diagnosed with clinically locally advanced tumours by digital rectal examination. World J urology:31:881–886
Zurück zum Zitat Yu KK et al (1997) Detection of extracapsular extension of prostate carcinoma with endorectal and phased-array coil MR imaging: multivariate feature analysis. Radiology 202(3):697 Yu KK et al (1997) Detection of extracapsular extension of prostate carcinoma with endorectal and phased-array coil MR imaging: multivariate feature analysis. Radiology 202(3):697
Metadaten
Titel
Primärdiagnostik
verfasst von
Dr. med. Anja Weidner
Dr. med. Ali Abaci
Ingrid, cand. med. Natalie Donk
Prof. Dr. med. Ulrike Attenberger
Copyright-Jahr
2017
Verlag
Springer Berlin Heidelberg
DOI
https://doi.org/10.1007/978-3-662-50468-0_3

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