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01.12.2011 | Case report | Ausgabe 1/2011 Open Access

Journal of Medical Case Reports 1/2011

Primary adenocarcinoma in the ileostomy of a woman with familial adenomatous polyposis: a case report and literature review

Zeitschrift:
Journal of Medical Case Reports > Ausgabe 1/2011
Autoren:
Ahmed Hammad, Raed Tayyem, Peter J Milewski, Shanmugavelu Gunasekaran
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1752-1947-5-556) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors' contributions

AH performed literature searches, wrote the paper, and assisted in the operation. RT contributed in writing the amendments and in revising the manuscript. PJM and SG performed the operation and supervised the final revision of the paper. All authors read and approved the final manuscript.

Abstract

Introduction

Ileal adenomas associated with familial adenomatous polyposis are a common finding. Many recent studies following panproctocolectomy for familial adenomatous polyposis have confirmed the presence of multiple ileal adenomas and an increase in ileal mucosal proliferation. In this study, we present a case of invasive adenocarcinoma arising in a severely dysplastic tubulovillous adenoma in the ileostomy of a patient with familial adenomatous polyposis; also, we present a literature review. To the best of our knowledge, only very few cases have been reported in the literature.

Case presentation

A 59-year-old Caucasian woman developed a primary adenocarcinoma in her ileostomy, complicating the stoma 31 years after its formation.

Conclusions

Primary adenocarcinoma following panproctocolectomy for familial adenomatous polyposis is a very rare clinical entity. The risk of developing adenocarcinoma in those patients increases with time. Patient education and medical examination of the stoma are of paramount importance and should be implemented early with the need of designing a surveillance protocol for early detection and management of ileal adenomas, especially in longstanding stomas.

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