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Erschienen in: Clinical Journal of Gastroenterology 4/2017

26.05.2017 | Case Report

Primary malignant melanoma of esophagus following chemoradiotherapy for esophageal squamous cell carcinoma: report of a case

verfasst von: Shinichiro Imai, Akira Suzuki, Yuta Yamamoto, Makoto Koyama, Satoshi Sugiyama, Masato Kitazawa, Yusuke Miyagawa, Shinichi Miyagawa

Erschienen in: Clinical Journal of Gastroenterology | Ausgabe 4/2017

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Abstract

Primary malignant melanoma of the esophagus (PMME) is a rare neoplasm. We observed a case of PMME that had occurred at an irradiated site in the thoracic esophagus. The patient was a 74-year-old man who had received definitive chemoradiotherapy for esophageal squamous cell carcinoma at the age of 68, and had completely recovered. Six years later, via periodic upper gastrointestinal endoscopy, he had been diagnosed with esophageal tumors. After the patient underwent esophagectomy, the removed esophageal tumors were immunohistologically diagnosed as PMME, and most of the tumor was observed to be located within the irradiated area corresponding to the previous radiotherapy. The patient has been free of recurrence and metastasis and alive for 20 months after the second surgery without any additional treatment. The clinical course of this patient suggests that therapeutic radiation may be a factor in the occurrence of PMME.
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Metadaten
Titel
Primary malignant melanoma of esophagus following chemoradiotherapy for esophageal squamous cell carcinoma: report of a case
verfasst von
Shinichiro Imai
Akira Suzuki
Yuta Yamamoto
Makoto Koyama
Satoshi Sugiyama
Masato Kitazawa
Yusuke Miyagawa
Shinichi Miyagawa
Publikationsdatum
26.05.2017
Verlag
Springer Japan
Erschienen in
Clinical Journal of Gastroenterology / Ausgabe 4/2017
Print ISSN: 1865-7257
Elektronische ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-017-0751-2

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