01.12.2011 | Case report | Ausgabe 1/2011 Open Access
Primary parotid gland lymphoma: a case report
- Zeitschrift:
- Journal of Medical Case Reports > Ausgabe 1/2011
Wichtige Hinweise
Electronic supplementary material
The online version of this article (doi:10.1186/1752-1947-5-380) contains supplementary material, which is available to authorized users.
Competing interests
The authors declare that they have no competing interests.
Authors' contributions
PKo prepared the manuscript and reviewed it for publication. ES performed the review of the literature. PKa collected the patients' data. GK supervised the general management and follow-up of the patient and the writing of the manuscript. All authors read and approved the final manuscript.
Abstract
Introduction
Mucosa associated lymphoid tissue lymphomas are the most common lymphomas of the salivary glands. The benign lymphoepithelial lesion is also a lymphoproliferative disease that develops in the parotid gland. In the present case report, we describe one case of benign lymphoepithelial lesion with a subsequent low transformation to grade mucosa associated lymphoid tissue lymphoma appearing as a cystic mass in the parotid gland.
Case presentation
A 78-year-old Caucasian female smoker was referred to our clinic with a non-tender left facial swelling that had been present for approximately three years. The patient underwent resection of the left parotid gland with preservation of the left facial nerve through a preauricular incision. The pathology report was consistent with a low-grade marginal-zone B-cell non-Hodgkin lymphoma (mucosa associated lymphoid tissue lymphoma) following benign lymphoepithelial lesion of the gland.
Conclusions
Salivary gland mucosa associated lymphoid tissue lymphoma should be considered in the differential diagnosis of cystic or bilateral salivary gland lesions. Parotidectomy is recommended in order to treat the tumor and to ensure histological diagnosis for further follow-up planning. Radiotherapy and chemotherapy should be considered in association with surgery in disseminated forms or after removal.