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01.12.2015 | Case report | Ausgabe 1/2015 Open Access

BMC Urology 1/2015

Primary renal squamous cell carcinoma mimicking the renal cyst: a case report and review of the recent literature

BMC Urology > Ausgabe 1/2015
Peng Jiang, Chaojun Wang, Shanwen Chen, Jun Li, Jianjian Xiang, Liping Xie
Wichtige Hinweise

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

PJ and JJX drafted the manuscript. JJX provided imaging description and figures. CJW, SWC and JL assisted with manuscript preparation and literatures collection. LPX revised the manuscript. All authors have read and approved the final manuscript.



Renal squamous cell carcinoma is a rare neoplasm with poor prognosis. Chronic irritation from nephrolithiasis and/or pyelonephritis is the leading cause.

Case presentation

We described a 51-year-old male patient who was admitted because of left flank pain. Ultrasonography showed a renal cyst containing calculus. However, contrast-enhanced ultrasonography and CT scan revealed an irregular-shaped mass derived from a calculi-containing cyst. Ultrasound guided biopsy confirmed the diagnosis of renal squamous cell carcinoma. The patient refused any further therapeutic management and died six months later.


Our present case emphasizes that the careful diagnostic work-up and use of multiple imaging modalities in cases of unusual renal calculi is quite necessary, since they may carry the risk of co-existing hidden malignancy.
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