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01.12.2012 | Case report | Ausgabe 1/2012 Open Access

World Journal of Surgical Oncology 1/2012

Primary thyroid angiosarcoma: an unusual localization

Zeitschrift:
World Journal of Surgical Oncology > Ausgabe 1/2012
Autoren:
Pasquale Petronella, Marco Scorzelli, Rossella Luise, Giuseppe Iannaci, Patrizia Sapere, Marco Ferretti, Rosaria Maria Anna Costanzo, Fulvio Freda, Silvestro Canonico, Raffaele Rossiello
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1477-7819-10-73) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors’ contributions

PP oversaw the entire clinical and surgical, contributed to the content of the manuscript and critically reviewed the manuscript. MS oversaw the entire clinical and surgical, contributed to the content of the manuscript and critically reviewed the manuscript. RL oversaw the histology, contributed to the content of the manuscript and critically reviewed the manuscript. GI oversaw the histology, contributed to the content of the manuscript and critically reviewed the manuscript. PS edited the histology, contributed to the content of the manuscript and critically reviewed the manuscript. MF oversaw the entire clinical and surgical, contributed to the content of the manuscript and critically reviewed the manuscript. RC oversaw the histology, contributed to the content of the manuscript and critically reviewed the manuscript. FF oversaw the entire clinical and surgical, contributed to the content of the manuscript and critically reviewed the manuscript. SC oversaw the entire clinical and surgical, contributed to the content of the manuscript and critically reviewed the manuscript. RR oversaw the histology, contributed to the content of the manuscript and critically reviewed the manuscript. All authors read and approved the final manuscript.

Abstract

The finding of thyroid nodules is a very common occurrence in routine clinical practice. Approximately 5% to 7% of the entire population have thyroid nodules. Vascular lesions are one of the most controversial issues in thyroid pathology. These include benign lesions such as hemangiomas and, rarely, malignant tumors such as angiosarcomas or undifferentiated angiosarcomatoid carcinomas. In particular, angiosarcoma of the thyroid gland is a rare, highly aggressive malignant vascular tumor and in Italy the greatest geographical incidence of this lesion is witnessed near the Alps. Here, a case of thyroid angiosarcoma in a 71-year-old man with a history of goiter for about 20 years is described. The unusual localization of this lesion, the difficulties in reaching a definitive diagnosis for this particular histological type of primary tumor and a history of long-standing multinodular goiter in thyroid of an older man from outside the Alpine region prompted us to report this case of thyroid angiosarcoma mainly to discuss surgical, histopathological and immunohistochemical features.
Zusatzmaterial
Authors’ original file for figure 1
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Authors’ original file for figure 2
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Authors’ original file for figure 3
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Authors’ original file for figure 4
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Literatur
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