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Erschienen in: Indian Journal of Pediatrics 1/2019

15.01.2018 | Review Article

Principles of Management of Central Nervous System Infections

verfasst von: Sunit Singhi, Suresh Kumar Angurana

Erschienen in: Indian Journal of Pediatrics | Ausgabe 1/2019

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Abstract

CNS infections in children are medical emergency and are associated with high mortality and morbidity. For diagnosis, a high index of suspicion is required. Clinical assessment should be supplemented by laboratory investigations including CSF Gram stain and cultures, blood culture, PCR on CSF, serological tests, and imaging. Commonly associated life threatening complications include coma, seizure, raised intracranial pressure (ICP), focal deficits, shock, respiratory failure, and fluid and electrolyte abnormalities. Immediate management should first address control of airway, breathing and circulation; protocolized management of raised ICP and status epilepticus; maintaining adequate intravascular volume; and close monitoring for early detection of complications. Appropriate antimicrobial agents should be administered promptly according to the suspected pathogen. Clinical evaluation, laboratory workup, specific antimicrobial therapy, supportive treatment, and management of associated complications should go hand in hand in a protocolized way for better outcome.
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Metadaten
Titel
Principles of Management of Central Nervous System Infections
verfasst von
Sunit Singhi
Suresh Kumar Angurana
Publikationsdatum
15.01.2018
Verlag
Springer India
Erschienen in
Indian Journal of Pediatrics / Ausgabe 1/2019
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-017-2583-y

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