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01.12.2017 | Letter to the Editor | Ausgabe 1/2017 Open Access

Orphanet Journal of Rare Diseases 1/2017

Probable DRESS syndrome induced by IL-1 inhibitors

Orphanet Journal of Rare Diseases > Ausgabe 1/2017
L. Polivka, J. S. Diana, A. Soria, C. Bodemer, P. Quartier, S. Fraitag, B. Bader-Meunier


Interleukin (IL)-1 inhibitors have been increasingly used for treating autoinflammatory diseases during the last 10 years, but the spectrum of their possible side effects is not yet fully known. Here, we bring physicians’ attention to a new severe complication of IL-1 inhibitors, manifesting as a probable drug reaction with eosinophilia and systemic symptoms (DRESS) in two patients.
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