Cent Eur Neurosurg 2010; 71(4): 219-221
DOI: 10.1055/s-0029-1242760
Case Report

© Georg Thieme Verlag KG Stuttgart · New York

Rosette-Forming Glioneuronal Tumor of the Fourth Ventricle

N. G. Rainov1 , T. Wagner2 , V. Heidecke1
  • 1Department of Neurosurgery, Klinikum Augsburg, Augsburg, Germany
  • 2Department of Pathology, Klinikum Augsburg, Augsburg, Germany
Further Information

Publication History

Publication Date:
31 March 2010 (online)

Introduction

Komori et al. (2002) were the first authors to recognize the existence of a new brain tumor entity, rosette-forming glioneuronal tumor (RGNT) of the fourth ventricle. The authors described 11 cases of this distinctive tumor of the posterior fossa [6]. A few further RGNT cases were published in the following 5 years [1] [2] [4] [5] [8] [10], eventually leading to the inclusion of RGNT in the 4th edition of the WHO brain tumor classification as a benign primary brain tumor classified as WHO grade 1 [7] [9].

We describe here the clinical and neuroradiological features of a further patient with RGNT of the fourth ventricle. Our report may contribute to establishing the natural history of these tumors and identifying the best course of treatment.

References

  • 1 Adachi J, Nishikawa R, Hirose T. et al . Mixed neuronal-glial tumor of the fourth ventricle and successful treatment of postoperative mutism with bromocriptine: case report.  Surg Neurol. 2005;  63 375-379
  • 2 Albanese A, Mangiola A, Pompucci A. et al . Rosette-forming glioneuronal tumour of the fourth ventricle: report of a case with clinical and surgical implications.  J Neurooncol. 2005;  71 195-197
  • 3 Amemiya S, Shibahara J, Aoki S. et al . Recently established entities of central nervous system tumors: review of radiological findings.  J Comput Assist Tomogr. 2008;  32 279-285
  • 4 Jacques TS, Eldridge C, Patel A. et al . Mixed glioneuronal tumour of the fourth ventricle with prominent rosette formation.  Neuropathol Appl Neurobiol. 2006;  32 217-220
  • 5 Johnson M, Pace J, Burroughs JF. Fourth ventricle rosette-forming glio­neuronal tumor. Case report.  J Neurosurg. 2006;  105 129-131
  • 6 Komori T, Scheithauer BW, Hirose T. A rosette-forming glioneuronal tumor of the fourth ventricle: infratentorial form of dysembryoplastic neuroepithelial tumor?.  Am J Surg Pathol. 2002;  26 582-591
  • 7 Louis DN, Ohgaki H, Wiestler OD. et al . The 2007 WHO Classification of Tumours of the Central Nervous System.  Acta Neuropathol. 2007;  114 97-109
  • 8 Preusser M, Dietrich W, Czech T. et al . Rosette-forming glioneuronal tumor of the fourth ventricle.  Acta Neuropathol. 2003;  106 506-508
  • 9 Rosenblum MK. The 2007 WHO Classification of Nervous System Tumors: newly recognized members of the mixed glioneuronal group.  Brain Pathol. 2007;  17 308-313
  • 10 Vajtai I, Arnold M, Kappeler A. et al . Rosette-forming glioneuronal tumor of the fourth ventricle: Report of two cases with a differential diagnostic overview.  Pathol Res Pract. 2007;  203 613-619

Correspondence

Dr. N. G. Rainov

Department of Neurosurgery

Klinikum Augsburg

Stenglinstraße 2

86156 Augsburg

Germany

Phone: +498214002853

Fax: +498214003314

Email: nikolai.rainov@klinikum-augsburg.de

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