Semin intervent Radiol 2012; 29(03): 226-230
DOI: 10.1055/s-0032-1326933
Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.

Emergent Management of Empyema

Osman Ahmed
1   Department of Radiology, University of Chicago, Chicago, Illinois
,
Steven Zangan
1   Department of Radiology, University of Chicago, Chicago, Illinois
› Author Affiliations
Further Information

Publication History

Publication Date:
16 October 2012 (online)

Abstract

Empyema is a frankly purulent infection of the pleural space most often occurring secondary to parapneumonic effusion. Imaging, specifically contrast-enhanced computed tomography, plays a critical role in diagnosis with a “split pleura” sign being highly suggestive in the appropriate clinical setting. Diagnostic thoracentesis with culture and Gram stain further guides appropriate antibiotic therapy. Therapeutic drainage with small-bore tube thoracostomy has been shown to be a safe and effective treatment of early stage empyema. Augmentation of tube placement with intrapleural fibrinolytics and mucolytics facilitates catheter drainage by degrading loculations and decreasing fluid viscosity, respectively.

 
  • References

  • 1 Kraus GJ. The split pleura sign. Radiology 2007; 243 (1) 297-298
  • 2 Huang H-C, Chang H-Y, Chen C-W, Lee C-H, Hsiue T-R. Predicting factors for outcome of tube thoracostomy in complicated parapneumonic effusion for empyema. Chest 1999; 115 (3) 751-756
  • 3 Braun MA. Interventions in the pleural space. J Vasc Interv Radiol 1997; 8: 154-160
  • 4 Temes RT, Follis F, Kessler RM, Pett Jr SB, Wernly JA. Intrapleural fibrinolytics in management of empyema thoracis. Chest 1996; 110 (1) 102-106
  • 5 Gervais DA, Levis DA, Hahn PF, Uppot RN, Arellano RS, Mueller PR. Adjunctive intrapleural tissue plasminogen activator administered via chest tubes placed with imaging guidance: effectiveness and risk for hemorrhage. Radiology 2008; 246 (3) 956-963
  • 6 Rahman NM, Maskell NA, West A , et al. Intrapleural use of tissue plasminogen activator and DNase in pleural infection. N Engl J Med 2011; 365 (6) 518-526
  • 7 Lardinois D, Gock M, Pezzetta E , et al. Delayed referral and gram-negative organisms increase the conversion thoracotomy rate in patients undergoing video-assisted thoracoscopic surgery for empyema. Ann Thorac Surg 2005; 79 (6) 1851-1856
  • 8 Lawrence DR, Ohri SK, Moxon RE, Townsend ER, Fountain SW. Thoracoscopic debridement of empyema thoracis. Ann Thorac Surg 1997; 64 (5) 1448-1450
  • 9 Striffeler H, Gugger M, Im Hof V, Cerny A, Furrer M, Ris HB. Video-assisted thoracoscopic surgery for fibrinopurulent pleural empyema in 67 patients. Ann Thorac Surg 1998; 65 (2) 319-323
  • 10 Tong BC, Hanna J, Toloza EM , et al. Outcomes of video-assisted thoracoscopic decortication. Ann Thorac Surg 2010; 89 (1) 220-225