New Pyrrolizidine Alkaloids from Heliotropium crassifolium

 

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Abstract

Heliotropium crassifolium Boiss, (Boraginaceae) from a population of Ilam, western region of Iran was studied for pyrrolizidine alklaoids (PAs). Four alkaloids have been identified: europine 1, europine N-oxide 2 and a new pyrrolizidine alkaloids ilamine 3 and its N-oxide 4, respectively. Their structures were elucidated by IR, ¹H-NMR and EIMS data.

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Dr. Hassan Farsam

Prof. of Pharm. Chem. Faculty of Pharmacy Tehran University of Medical Sciences

Tehran

Iran

P.O. Box: 14155-6451

Email: farsam@sina.tums.ac.ir

Phone: +98 21 6461178