Hyperthyroidism with Fibrous Dysplasia: An unusual presentation of McCune-Albright syndrome

 

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Abstract

McCune-Albright Syndrome (MAS) is a sporadic disorder characterized by a triad of poly/monostotic fibrous dysplasia, café-au-lait macules, and hyperfunctioning endocrinopathies. Hyperthyroidism as a manifestation of endocrine hyperfunction in MAS is uncommon. We report a patient who had polyostotic fibrous dysplasia with multiple pathological fractures and hyperthyroidism. She underwent surgery for hyperthyroidism and received pamidronate therapy with remarkable relief in bone pains and without any new fractures during her subsequent follow up of 3 years.

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Correspondence

A. Bhansali

Head, Department of Endocrinology

Postgraduate Institute of Medical Education and Research

Chandigarh- 160012

India

Phone: +91/172/74 75 85/ 600 / 65 83

Fax: +91/172/74 44 01

Email: anilbhansali_endocrine@rediffmail.com