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10.11.2017 | Original Paper | Ausgabe 3/2018

Clinical Research in Cardiology 3/2018

Prognostic impact of atrial fibrillation in cardiogenic shock complicating acute myocardial infarction: a substudy of the IABP-SHOCK II trial

Zeitschrift:
Clinical Research in Cardiology > Ausgabe 3/2018
Autoren:
Suzanne de Waha, Katharina Schoene, Georg Fuernau, Steffen Desch, Ingo Eitel, Janine Pöss, Roza Meyer-Saraei, Charlotte Eitel, Roland Tilz, Gerhard Schuler, Karl Werdan, Steffen Schneider, Taoufik Ouarrak, Uwe Zeymer, Holger Thiele
Wichtige Hinweise
Suzanne de Waha, Katharina Schoene, Uwe Zeymer and Holger Thiele are equally contributing authors.

Abstract

Background

Aim of the current study was to analyse the impact of atrial fibrillation (AF) on prognosis in patients with cardiogenic shock (CS) complicating acute myocardial infarction (AMI), which has never been investigated yet.

Methods

The current analysis is a substudy of the IABP-SHOCK II trial. Patients were grouped according to the presence or absence of AF. The primary endpoint was all-cause mortality at 30-day follow-up. Secondary endpoints included all-cause mortality, recurrent myocardial infarction, repeat revascularisation, and stroke at 12 months.

Results

AF was documented in 28.2% (n = 169) of all 600 patients initially enrolled in the IABP-SHOCK II trial. There were no significant differences with respect to mortality at 30 days and 12 months between patients with and without AF (p = 0.81, p = 0.74). Similarly, the rates of recurrent myocardial infarction, repeat revascularisation, and stroke did not differ between groups (all p > 0.05). There was no interaction of intraaortic balloon counterpulsation (IABP) and no IABP in patients with or without AF with respect to clinical outcome at 30 days and 12 months (p > 0.05).

Conclusion

AF is not associated with clinical outcome at 30 days and 12 months in CS complicating AMI.

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