Background
Methods
Selection of cases
Immunohistochemistry
Follow-up and recurrence
Statistical analysis
Results
n (%) | |
---|---|
Age (years)a | 63.61 ± 14.49 |
Follow up (months)a, b | 22.76 ± 13.66 |
EFGR (%)a | 14.50 ± 22.41 |
Gender | |
Male | 91(72.2) |
Female | 35(27.8) |
Specimen Type | |
Transurethral resection | 121(96) |
Radical Cystectomy | 5(4) |
Tumor Grade | |
Low Grade Papillary Urothelial Carcinoma | 65(51.6) |
High Grade Papillary Urothelial Carcinoma | 61(48.4) |
Lamina Propria Invasion | |
Present | 35(27.8) |
Absent | 91(72.2) |
Deep Muscle Invasion | |
Present | 22(17.5) |
Absent | 59(46.8) |
Can’t Assessed | 45(35.7) |
Recurrence (n = 58) | |
Yes | 25(43.1) |
No | 33(56.9) |
Survival Status (n = 58) | |
Alive | 49(84.5) |
Expired | 9(15.5) |
EFGR Expression n (%) | P-Value | ||||
---|---|---|---|---|---|
No Expression (n = 74) | Low EFGR Expression (n = 19) | High EFGR expression (n = 33) | Total (n = 126) | ||
Gender | |||||
Male | 54(73) | 14(73.7) | 23(69.7) | 91(72.2) | 0.930 |
Female | 20(27) | 5(26.3) | 10(30.3) | 35(27.8) | |
Age Groupa | |||||
≤ 25 years | 1(1.4) | 0(0) | 0(0) | 0(0) | 0.263 |
26–50 years | 21(28.4) | 2(10.5) | 2(10.5) | 5(15.2) | |
> 50 years | 52(70.3) | 17(89.5) | 17(89.5) | 28(84.8) | |
Specimen Type a | |||||
Transurethral resection | 72(97.3) | 19(100) | 30(90.9) | 121(96) | 0.209 |
Radical Cystectomy | 2(2.7) | 0(0) | 3(9.1) | 5(4) | |
Tumor Grade | |||||
Low Grade | 48(64.9) | 9(47.4) | 8(24.2) | 65(51.6) | 0.000 |
High Grade | 26(35.1) | 10(52.6) | 25(75.8) | 61(48.4) | |
Lamina Propria Invasion | |||||
Present | 15(20.3) | 3(15.8) | 17(51.5) | 35(27.8) | 0.002 |
Absent | 59(79.7) | 16(84.2) | 16(48.5) | 91(72.2) | |
Deep Muscle Invasion a | |||||
Present | 9(12.2) | 1(5.3) | 12(36.4) | 22(17.5) | 0.012 |
Absent | 38(51.4) | 12(63.2) | 9(27.3) | 59(46.8) | |
Can’t Assessed | 27(36.5) | 6(31.6) | 12(36.4) | 45(35.7) | |
Recurrence (n = 58) a | |||||
Yes | 15(40.5) | 0(0) | 10(66.7) | 25(43.1) | 0.017 |
No | 22(59.5) | 6(100) | 5(33.3) | 33(56.9) | |
Survival Status (n = 58) a | |||||
Alive | 32(86.5) | 6(100) | 11(73.3) | 49(84.5) | 0.398 |
Expired | 5(13.5) | 0(0) | 4(26.7) | 9(15.5) |