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02.02.2024 | Original Article

Prognostic significance of left atrial strain combined with left ventricular strain using cardiac magnetic resonance feature tracking in patients with heart failure with preserved ejection fraction

verfasst von: Masataka Katahira, Kenji Fukushima, Takatoyo Kiko, Ryo Yamakuni, Keiichiro Endo, Akiomi Yoshihisa, Shiro Ishii, Hiroshi Ito, Yasuchika Takeishi

Erschienen in: Heart and Vessels | Ausgabe 5/2024

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Abstract

We aimed to evaluate the prognostic value of left ventricular global longitudinal strain (LVGLS) and left atrial strain (LAS) obtained from magnetic resonance imaging (MRI) feature tracking in patients with heart failure with preserved ejection fraction (HFpEF). We retrospectively enrolled consecutive patients with HFpEF admitted to our hospital who underwent cardiac MRI. LVGLS and LAS were obtained from cine MRI by feature tracking. The end point was defined as a composite of all-cause death, myocardial infarction, and hospitalization due to decompensated HF. One-hundred patients with HFpEF were enrolled. Mean LVGLS and LAS were − 13.7 ± 3.7% and 22.5 ± 11.6%, respectively. During follow-up of 4.4 ± 1.9 years, 24 events occurred. Multivariate Cox proportional hazards model analysis demonstrated LAS was independently associated with adverse cardiac events. Kaplan–Meier curve analysis revealed that the patients with both LVGLS and LAS worse than the median (LVGLS ≥ − 12.2% and LAS ≤ 13.8%) had a significantly lower event-free rate compared to those with preserved strain (Log-rank P < 0.001). Simultaneous assessment of LVGLS and LAS using MRI was useful for risk stratification in the patients with HFpEF.
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Metadaten
Titel
Prognostic significance of left atrial strain combined with left ventricular strain using cardiac magnetic resonance feature tracking in patients with heart failure with preserved ejection fraction
verfasst von
Masataka Katahira
Kenji Fukushima
Takatoyo Kiko
Ryo Yamakuni
Keiichiro Endo
Akiomi Yoshihisa
Shiro Ishii
Hiroshi Ito
Yasuchika Takeishi
Publikationsdatum
02.02.2024
Verlag
Springer Japan
Erschienen in
Heart and Vessels / Ausgabe 5/2024
Print ISSN: 0910-8327
Elektronische ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-023-02351-9

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