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01.12.2012 | Original investigation | Ausgabe 1/2012 Open Access

Cardiovascular Diabetology 1/2012

Prognostic significance of the Complex "Visceral Adiposity Index" vs. simple anthropometric measures: Tehran lipid and glucose study

Zeitschrift:
Cardiovascular Diabetology > Ausgabe 1/2012
Autoren:
Bozorgmanesh Mohammadreza, Hadaegh Farzad, Khalili Davoud, Azizi Fereidoun Prof
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1475-2840-11-20) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors' contributions

MR conceptualized and designed the study, prepared and analyzed data, interpreted the results obtained, and drafted the manuscript. FH, DK, and FA reviewed/edited the manuscript. All authors gave their final approval of the version to be published. All authors read and approved the final manuscript

Abstract

Background

Visceral adiposity index (VAI) has recently been suggested to be used as a surrogate of visceral adiposity. We examined if VAI could improve predictive performances for CVD of the Framingham's general CVD algorithm (a multivariate model incorporating established CVD risk factors). We compared the predictive abilities of the VAI with those of simple anthropometric measures i.e. BMI, waist-to-height ratio (WHtR) or waist-to-hip ratio (WHpR).

Design and methods

In a nine-year population-based follow-up, 6 407 (2 778 men) participants, free of CVD at baseline, aged ≥ 30 years were eligible for the current analysis. The risk of CVD was estimated by incorporating VAI, BMI, WHpR, and WHtR, one at a time, into multivariate accelerated failure time models.

Results

We documented 534 CVD events with the annual incidence rate (95%CIs) being 7.3 (6.4-8.3) among women and 13.0 (11.7-14.6) among men. Risk of future CVD increased with increasing levels of VAI among both men and women. VAI was associated with multivariate-adjusted increased risk of incident CVD among women. However, the magnitude of risk conferred by VAI was not significantly higher than those conferred by BMI, WHpR, or WHtR. Among men, after adjustment for established CVD risk factors, VAI was no longer associated with increased risk of CVD. VAI failed to add to the predictive ability of the Framingham general CVD algorithm.

Conclusions

Using VAI instead of simple anthropometric measures may lead to loss of much information needed for predicting incident CVD.
Zusatzmaterial
Authors’ original file for figure 1
12933_2011_465_MOESM1_ESM.pdf
Authors’ original file for figure 2
12933_2011_465_MOESM2_ESM.pdf
Authors’ original file for figure 3
12933_2011_465_MOESM3_ESM.pdf
Literatur
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