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Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases 4/2017

06.12.2016 | Review

Prophylactic antibiotics for percutaneous endovascular procedures

verfasst von: N. S. Greaves, E. Katsogridakis, B. Faris, D. Murray

Erschienen in: European Journal of Clinical Microbiology & Infectious Diseases | Ausgabe 4/2017

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Abstract

Percutaneous endovascular techniques are used increasingly in the vascular armamentarium. Commonly performed as day case procedures under local anaesthetic, they are suited to the highly co-morbid vascular patient population. Furthermore, technological advances have resulted in ever improving outcomes for aneurysmal and occlusive disease. Endovascular procedures such as endovascular aneurysm repair or iliac artery stenting are traditionally associated with reduced infectious complications compared to equivalent open techniques. However, when they do occur, they are equally devastating and often associated with limb loss or death since the only effective treatment is removal of all infected material. The use of prophylactic antibiotics to reduce infectious complications in open surgery has a strong evidence base, but there is no equivalent data for percutaneous endovascular procedures. The Society of Interventional Radiology published formal guidelines for adult antibiotic prophylaxis in 2010. Based on relatively poor quality studies, they nevertheless represent the first official guidance in the field and stress the need for large randomised controlled trials to further guide the debate. Broadly, the benefits of reduced infectious complications must be balanced against the fiscal cost of increased antimicrobial usage, promotion of multi-drug resistant organisms and patient side-effect profiles. The number needed to treat to prevent one infection is high yet without it a small but significant number of patients will suffer serious adverse outcomes secondary to infection of endovascular prostheses. This review article aims to summarise the evidence around the use of prophylactic antibiotics in percutaneous endovascular procedures.
Literatur
1.
Zurück zum Zitat Hogg ME, Peterson BG, Pearce WH et al (2007) Bare metal stent infections: case report and review of the literature. J Vasc Surg 46(4):813–820CrossRefPubMed Hogg ME, Peterson BG, Pearce WH et al (2007) Bare metal stent infections: case report and review of the literature. J Vasc Surg 46(4):813–820CrossRefPubMed
2.
Zurück zum Zitat McDermott VG, Schuster MG, Smith TP (1997) Antibiotic prophylaxis in vascular and interventional radiology. AJR Am J Roentgenol 169:31–38CrossRefPubMed McDermott VG, Schuster MG, Smith TP (1997) Antibiotic prophylaxis in vascular and interventional radiology. AJR Am J Roentgenol 169:31–38CrossRefPubMed
3.
Zurück zum Zitat Fiorani P, Speziale F, Calisti A (2003) Endovascular graft infection: preliminary results of an international enquiry. J Endovasc Ther 10:919–927CrossRefPubMed Fiorani P, Speziale F, Calisti A (2003) Endovascular graft infection: preliminary results of an international enquiry. J Endovasc Ther 10:919–927CrossRefPubMed
4.
Zurück zum Zitat Spies JB, Rosen R, Lebowitz AS (1988) Antibiotic prophylaxis in vascular and interventional radiology: a rational approach. Radiology 166:301–387CrossRef Spies JB, Rosen R, Lebowitz AS (1988) Antibiotic prophylaxis in vascular and interventional radiology: a rational approach. Radiology 166:301–387CrossRef
5.
Zurück zum Zitat Venkatesan AM, Kundu S, Sacks D et al (2010) Practice guideline for adult antibiotic prophylaxis during vascular and interventional radiology procedures. J Vasc Interv Radiol 21:1611–1630CrossRefPubMed Venkatesan AM, Kundu S, Sacks D et al (2010) Practice guideline for adult antibiotic prophylaxis during vascular and interventional radiology procedures. J Vasc Interv Radiol 21:1611–1630CrossRefPubMed
6.
Zurück zum Zitat Hicks RCJ, Greenhalgh RM (1997) The pathogenesis of vascular graft infection. Eur J Vasc Endovasc Surg 14(Suppl A):5–9CrossRefPubMed Hicks RCJ, Greenhalgh RM (1997) The pathogenesis of vascular graft infection. Eur J Vasc Endovasc Surg 14(Suppl A):5–9CrossRefPubMed
7.
Zurück zum Zitat Stewart AH, Eyers PS, Earnshaw JJ (2007) Prevention of infection in peripheral arterial reconstruction: a systematic review and meta-analysis. J Vasc Surg 46:148–155CrossRefPubMed Stewart AH, Eyers PS, Earnshaw JJ (2007) Prevention of infection in peripheral arterial reconstruction: a systematic review and meta-analysis. J Vasc Surg 46:148–155CrossRefPubMed
8.
Zurück zum Zitat O’Connor S, Andrew P, Batt M (2006) A systematic review and meta-analysis of treatments for aortic graft infections. J Vasc Surg 44:38–45CrossRefPubMed O’Connor S, Andrew P, Batt M (2006) A systematic review and meta-analysis of treatments for aortic graft infections. J Vasc Surg 44:38–45CrossRefPubMed
9.
Zurück zum Zitat Scottish Intercollegiate Guidelines Network 104 (SIGN) (2014) Antibiotic prophylaxis in surgery: a national clinical guideline. SIGN, Edinburgh Scottish Intercollegiate Guidelines Network 104 (SIGN) (2014) Antibiotic prophylaxis in surgery: a national clinical guideline. SIGN, Edinburgh
10.
Zurück zum Zitat Sharif MA, Lee B, Lau LL (2007) Prosthetic stent graft infection after endovascular abdominal aortic aneurysm repair. J Vasc Surg 46:442–448CrossRefPubMed Sharif MA, Lee B, Lau LL (2007) Prosthetic stent graft infection after endovascular abdominal aortic aneurysm repair. J Vasc Surg 46:442–448CrossRefPubMed
11.
Zurück zum Zitat Ducasse E, Calisti A, Speziale F (2004) Aortoiliac stent graft infections: current problems and management. Ann Vasc Surg 18:521–526CrossRefPubMed Ducasse E, Calisti A, Speziale F (2004) Aortoiliac stent graft infections: current problems and management. Ann Vasc Surg 18:521–526CrossRefPubMed
12.
Zurück zum Zitat Jackson MR, Clagett GP (2001) Aortic graft infection. In: Cronenwett JL, Rutherford RB (eds) Decision making in vascular surgery. WB Saunders, Philadelphia, pp 186–191 Jackson MR, Clagett GP (2001) Aortic graft infection. In: Cronenwett JL, Rutherford RB (eds) Decision making in vascular surgery. WB Saunders, Philadelphia, pp 186–191
13.
Zurück zum Zitat Parsons RE, Sanchez LA, Marin ML (1996) Comparison of endovascular and conventional vascular prostheses in an experimental infection model. J Vasc Surg 24:920–926CrossRefPubMed Parsons RE, Sanchez LA, Marin ML (1996) Comparison of endovascular and conventional vascular prostheses in an experimental infection model. J Vasc Surg 24:920–926CrossRefPubMed
14.
Zurück zum Zitat Kirksey L, Brener B, Hertz S (2002) Prophylactic antibiotics prior to bacteraemia decrease endovascular graft infection in dogs. Vasc Endovasc Surg 36:171–178CrossRef Kirksey L, Brener B, Hertz S (2002) Prophylactic antibiotics prior to bacteraemia decrease endovascular graft infection in dogs. Vasc Endovasc Surg 36:171–178CrossRef
15.
Zurück zum Zitat Paget DS, Bukhari RH, Zayyat EJ (1999) Infectibility of endovascular stents following antibiotic prophylaxis or after arterial wall incorporation. Am J Surg 178:219–224CrossRefPubMed Paget DS, Bukhari RH, Zayyat EJ (1999) Infectibility of endovascular stents following antibiotic prophylaxis or after arterial wall incorporation. Am J Surg 178:219–224CrossRefPubMed
16.
Zurück zum Zitat Hearn AT, James KV, Lohr JM (1997) Endovascular stent infection with delayed bacterial challenge. Am J Surg 174:157–159CrossRefPubMed Hearn AT, James KV, Lohr JM (1997) Endovascular stent infection with delayed bacterial challenge. Am J Surg 174:157–159CrossRefPubMed
17.
Zurück zum Zitat Thibodeaux LC, James KV, Lohr JM (1996) Infection of endovascular stents in a swine model. Am J Surg 172:151–154CrossRefPubMed Thibodeaux LC, James KV, Lohr JM (1996) Infection of endovascular stents in a swine model. Am J Surg 172:151–154CrossRefPubMed
18.
Zurück zum Zitat Palmaz JC (1993) Intravascular stents: tissue-stent interactions and design considerations. AJR Am J Roentgenol 160:613–618CrossRefPubMed Palmaz JC (1993) Intravascular stents: tissue-stent interactions and design considerations. AJR Am J Roentgenol 160:613–618CrossRefPubMed
19.
Zurück zum Zitat Sohail MR, Khan AH, Holmes DR (2005) Infectious complications of percutaneous vascular closure devices. Mayo Clin Proc 80(8):1011–1015CrossRefPubMed Sohail MR, Khan AH, Holmes DR (2005) Infectious complications of percutaneous vascular closure devices. Mayo Clin Proc 80(8):1011–1015CrossRefPubMed
20.
Zurück zum Zitat McCauley CE, Steed DL, Webster MW (1984) Bacterial presence in aortic thrombus at elective aneurysm resection: is it clinically significant? Am J Surg 147:322–324CrossRef McCauley CE, Steed DL, Webster MW (1984) Bacterial presence in aortic thrombus at elective aneurysm resection: is it clinically significant? Am J Surg 147:322–324CrossRef
21.
Zurück zum Zitat Johanning JM, Franklin DP, Elmore JR (2001) Femoral artery infections associated with percutaneous arterial closure devices. J Vasc Surg 34:983–985CrossRefPubMed Johanning JM, Franklin DP, Elmore JR (2001) Femoral artery infections associated with percutaneous arterial closure devices. J Vasc Surg 34:983–985CrossRefPubMed
23.
Zurück zum Zitat Stewart A, Eyers PS, Earnshaw JJ (2006) Prevention of infection in arterial reconstruction. Cochrane Database Syst Rev 19(3), CD003073 Stewart A, Eyers PS, Earnshaw JJ (2006) Prevention of infection in arterial reconstruction. Cochrane Database Syst Rev 19(3), CD003073
24.
Zurück zum Zitat Zarrinpar A, Kerlan RK (2005) A guide to antibiotics for the interventional radiologist. Semin Interv Radiol 22(2):69–79CrossRef Zarrinpar A, Kerlan RK (2005) A guide to antibiotics for the interventional radiologist. Semin Interv Radiol 22(2):69–79CrossRef
26.
Zurück zum Zitat Ryan JM, Ryan BM, Smith T (2004) Antibiotic prophylaxis in interventional radiology. J Vasc Interv Radiol 15:547–556CrossRefPubMed Ryan JM, Ryan BM, Smith T (2004) Antibiotic prophylaxis in interventional radiology. J Vasc Interv Radiol 15:547–556CrossRefPubMed
27.
Zurück zum Zitat Goldmann DA, Weinstein RA, Wenzel RP (1996) Strategies to prevent and control the emergence and spread of antimicrobial-resistant organisms in hospitals: a challenge to hospital leadership. JAMA 275:234–240CrossRefPubMed Goldmann DA, Weinstein RA, Wenzel RP (1996) Strategies to prevent and control the emergence and spread of antimicrobial-resistant organisms in hospitals: a challenge to hospital leadership. JAMA 275:234–240CrossRefPubMed
28.
Zurück zum Zitat Shawker TH, Kluge RM, Ayella RJ (1974) Bacteraemia associated with angiography. JAMA 229:1090–1092CrossRefPubMed Shawker TH, Kluge RM, Ayella RJ (1974) Bacteraemia associated with angiography. JAMA 229:1090–1092CrossRefPubMed
29.
Zurück zum Zitat Sande MA, Levinson ME, Lukas DS (1969) Bacteraemia associated with cardiac catheterisation. N Engl J Med 281:1104–1106CrossRefPubMed Sande MA, Levinson ME, Lukas DS (1969) Bacteraemia associated with cardiac catheterisation. N Engl J Med 281:1104–1106CrossRefPubMed
30.
Zurück zum Zitat Frazee BW, Flaherty J (1990) Septic endarteritis of the femoral artery following angioplasty. Rev Infect Dis 13:620–623CrossRef Frazee BW, Flaherty J (1990) Septic endarteritis of the femoral artery following angioplasty. Rev Infect Dis 13:620–623CrossRef
31.
Zurück zum Zitat Becker GJ, Kovacs M, Mathison MN (2001) Risk stratification and outcomes of transluminal endografting for abdominal aortic aneurysm: 7-year experience and long term follow-up. J Vasc Interv Radiol 12:1033–1046CrossRefPubMed Becker GJ, Kovacs M, Mathison MN (2001) Risk stratification and outcomes of transluminal endografting for abdominal aortic aneurysm: 7-year experience and long term follow-up. J Vasc Interv Radiol 12:1033–1046CrossRefPubMed
Metadaten
Titel
Prophylactic antibiotics for percutaneous endovascular procedures
verfasst von
N. S. Greaves
E. Katsogridakis
B. Faris
D. Murray
Publikationsdatum
06.12.2016
Verlag
Springer Berlin Heidelberg
Erschienen in
European Journal of Clinical Microbiology & Infectious Diseases / Ausgabe 4/2017
Print ISSN: 0934-9723
Elektronische ISSN: 1435-4373
DOI
https://doi.org/10.1007/s10096-016-2848-9

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