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Erschienen in: Herz 4/2010

01.06.2010 | Schwerpunkt/CME

Proposed Mayo Clinic criteria for the diagnosis of Tako-Tsubo cardiomyopathy and long-term prognosis

verfasst von: M. Madhavan, A. Prasad, MD

Erschienen in: Herz | Ausgabe 4/2010

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Abstract

Tako-Tsubo cardiomyopathy (TTC) is a reversible cardiomyopathy with a clinical presentation indistinguishable from myocardial infarction. TTC is estimated to represent 1%–2% of patients presenting with acute myocardial infarction. It most commonly occurs in postmenopausal women and is frequently precipitated by a stressful event. Chest pain and dyspnea are the typical presenting symptoms. Transient ST-segment elevation on ECG and a small rise in cardiac biomarkers are common. Characteristic wall motion abnormalities extend beyond the territory of a single epicardial coronary artery in the absence of obstructive coronary lesions. Supportive treatment leads to spontaneous rapid recovery in nearly all patients. The prognosis is excellent, and recurrence occurs in < 10% of patients. In this article, we review the clinical features of TTC that form the basis of the Mayo Clinic diagnostic criteria, as well as the long-term prognosis for this type of cardiomyopathy.
Literatur
1.
2.
Zurück zum Zitat Prasad A (2007) Apical ballooning syndrome: an important differential diagnosis of acute myocardial infarction. Circulation 115:e56–e59PubMedCrossRef Prasad A (2007) Apical ballooning syndrome: an important differential diagnosis of acute myocardial infarction. Circulation 115:e56–e59PubMedCrossRef
3.
Zurück zum Zitat Dote K, Sato H, Tateishi H et al (1991) Myocardial stunning due to simultaneous multivessel coronary spasms: a review of 5 cases. J Cardiol 21:203–214PubMed Dote K, Sato H, Tateishi H et al (1991) Myocardial stunning due to simultaneous multivessel coronary spasms: a review of 5 cases. J Cardiol 21:203–214PubMed
4.
Zurück zum Zitat Hoyt J, Lerman A, Lennon RJ et al (2009) Left anterior descending artery length and coronary atherosclerosis in apical ballooning syndrome (Takotsubo/stress induced cardiomyopathy). Int J Cardiol, doi 10.1016/iycard2009.06.018 Hoyt J, Lerman A, Lennon RJ et al (2009) Left anterior descending artery length and coronary atherosclerosis in apical ballooning syndrome (Takotsubo/stress induced cardiomyopathy). Int J Cardiol, doi 10.1016/iycard2009.06.018
5.
Zurück zum Zitat Mitchell JH, Hadden TB, Wilson JM et al (2007) Clinical features and usefulness of cardiac magnetic resonance imaging in assessing myocardial viability and prognosis in Takotsubo cardiomyopathy (transient left ventricular apical ballooning syndrome). Am J Cardiol 100:296–301PubMedCrossRef Mitchell JH, Hadden TB, Wilson JM et al (2007) Clinical features and usefulness of cardiac magnetic resonance imaging in assessing myocardial viability and prognosis in Takotsubo cardiomyopathy (transient left ventricular apical ballooning syndrome). Am J Cardiol 100:296–301PubMedCrossRef
6.
Zurück zum Zitat Seth PS, Aurigemma GP, Krasnow JM et al (2003) A syndrome of transient left ventricular apical wall motion abnormality in the absence of coronary disease: a perspective from the United States. Cardiology 100:61–66PubMedCrossRef Seth PS, Aurigemma GP, Krasnow JM et al (2003) A syndrome of transient left ventricular apical wall motion abnormality in the absence of coronary disease: a perspective from the United States. Cardiology 100:61–66PubMedCrossRef
7.
Zurück zum Zitat Sharkey SW, Windenburg DC, Lesser JR et al (n d) Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy. J Am Coll Cardiol 55:333–341 Sharkey SW, Windenburg DC, Lesser JR et al (n d) Natural history and expansive clinical profile of stress (tako-tsubo) cardiomyopathy. J Am Coll Cardiol 55:333–341
8.
Zurück zum Zitat Wittstein IS, Thiemann DR, Lima JA et al (2005) Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med 352:539–548PubMedCrossRef Wittstein IS, Thiemann DR, Lima JA et al (2005) Neurohumoral features of myocardial stunning due to sudden emotional stress. N Engl J Med 352:539–548PubMedCrossRef
9.
Zurück zum Zitat Desmet WJ, Adriaenssens BF, Dens JA (2003) Apical ballooning of the left ventricle: first series in white patients. Heart 89:1027–1031PubMedCrossRef Desmet WJ, Adriaenssens BF, Dens JA (2003) Apical ballooning of the left ventricle: first series in white patients. Heart 89:1027–1031PubMedCrossRef
10.
Zurück zum Zitat El Mahmoud R, Mansencal N, Pilliere R et al (2008) Prevalence and characteristics of left ventricular outflow tract obstruction in Tako-Tsubo syndrome. Am Heart J 156:543–548CrossRef El Mahmoud R, Mansencal N, Pilliere R et al (2008) Prevalence and characteristics of left ventricular outflow tract obstruction in Tako-Tsubo syndrome. Am Heart J 156:543–548CrossRef
11.
Zurück zum Zitat Haghi D, Fluechter S, Suselbeck T et al (2007) Cardiovascular magnetic resonance findings in typical versus atypical forms of the acute apical ballooning syndrome (Takotsubo cardiomyopathy). Int J Cardiol 120:205–211PubMedCrossRef Haghi D, Fluechter S, Suselbeck T et al (2007) Cardiovascular magnetic resonance findings in typical versus atypical forms of the acute apical ballooning syndrome (Takotsubo cardiomyopathy). Int J Cardiol 120:205–211PubMedCrossRef
12.
Zurück zum Zitat Abe Y, Kondo M, Matsuoka R et al (2003) Assessment of clinical features in transient left ventricular apical ballooning. J Am Coll Cardiol 41:737–742PubMedCrossRef Abe Y, Kondo M, Matsuoka R et al (2003) Assessment of clinical features in transient left ventricular apical ballooning. J Am Coll Cardiol 41:737–742PubMedCrossRef
13.
Zurück zum Zitat Akashi YJ, Musha H, Kida K et al (2005) Reversible ventricular dysfunction takotsubo cardiomyopathy. Eur J Heart Fail 7:1171–1176PubMedCrossRef Akashi YJ, Musha H, Kida K et al (2005) Reversible ventricular dysfunction takotsubo cardiomyopathy. Eur J Heart Fail 7:1171–1176PubMedCrossRef
14.
Zurück zum Zitat Kurisu S, Sato H, Kawagoe T et al (2002) Tako-tsubo-like left ventricular dysfunction with ST-segment elevation: a novel cardiac syndrome mimicking acute myocardial infarction. Am Heart J 143:448–455PubMedCrossRef Kurisu S, Sato H, Kawagoe T et al (2002) Tako-tsubo-like left ventricular dysfunction with ST-segment elevation: a novel cardiac syndrome mimicking acute myocardial infarction. Am Heart J 143:448–455PubMedCrossRef
15.
Zurück zum Zitat Abdulla I, Kay S, Mussap C et al (2006) Apical sparing in tako-tsubo cardiomyopathy. Intern Med J 36:414–418PubMedCrossRef Abdulla I, Kay S, Mussap C et al (2006) Apical sparing in tako-tsubo cardiomyopathy. Intern Med J 36:414–418PubMedCrossRef
16.
Zurück zum Zitat Maron BJ, Towbin JA, Thiene G et al (2006) Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation 113:1807–1816PubMedCrossRef Maron BJ, Towbin JA, Thiene G et al (2006) Contemporary definitions and classification of the cardiomyopathies: an American Heart Association Scientific Statement from the Council on Clinical Cardiology, Heart Failure and Transplantation Committee; Quality of Care and Outcomes Research and Functional Genomics and Translational Biology Interdisciplinary Working Groups; and Council on Epidemiology and Prevention. Circulation 113:1807–1816PubMedCrossRef
17.
Zurück zum Zitat Azzarelli S, Galassi AR, Amico F et al (2006) Clinical features of transient left ventricular apical ballooning. Am J Cardiol 98:1273–1276PubMedCrossRef Azzarelli S, Galassi AR, Amico F et al (2006) Clinical features of transient left ventricular apical ballooning. Am J Cardiol 98:1273–1276PubMedCrossRef
18.
Zurück zum Zitat Bybee KA, Prasad A, Barsness GW et al (2004) Clinical characteristics and thrombolysis in myocardial infarction frame counts in women with transient left ventricular apical ballooning syndrome. Am J Cardiol 94:343–346PubMedCrossRef Bybee KA, Prasad A, Barsness GW et al (2004) Clinical characteristics and thrombolysis in myocardial infarction frame counts in women with transient left ventricular apical ballooning syndrome. Am J Cardiol 94:343–346PubMedCrossRef
19.
Zurück zum Zitat Elian D, Osherov A, Matetzky S et al (2006) Left ventricular apical ballooning: not an uncommon variant of acute myocardial infarction in women. Clin Cardiol 29:9–12PubMedCrossRef Elian D, Osherov A, Matetzky S et al (2006) Left ventricular apical ballooning: not an uncommon variant of acute myocardial infarction in women. Clin Cardiol 29:9–12PubMedCrossRef
20.
Zurück zum Zitat Parodi G, Del Pace S, Carrabba N et al (2007) Incidence, clinical findings, and outcome of women with left ventricular apical ballooning syndrome. Am J Cardiol 99:182–185PubMedCrossRef Parodi G, Del Pace S, Carrabba N et al (2007) Incidence, clinical findings, and outcome of women with left ventricular apical ballooning syndrome. Am J Cardiol 99:182–185PubMedCrossRef
21.
Zurück zum Zitat Pilliere R, Mansencal N, Digne F et al (2006) Prevalence of tako-tsubo syndrome in a large urban agglomeration. Am J Cardiol 98:662–665PubMedCrossRef Pilliere R, Mansencal N, Digne F et al (2006) Prevalence of tako-tsubo syndrome in a large urban agglomeration. Am J Cardiol 98:662–665PubMedCrossRef
22.
Zurück zum Zitat Elesber AA, Prasad A, Lennon RJ et al (2007) Four-year recurrence rate and prognosis of the apical ballooning syndrome. J Am Coll Cardiol 50:448–452PubMedCrossRef Elesber AA, Prasad A, Lennon RJ et al (2007) Four-year recurrence rate and prognosis of the apical ballooning syndrome. J Am Coll Cardiol 50:448–452PubMedCrossRef
23.
Zurück zum Zitat Gianni M, Dentali F, Grandi AM et al (2006) Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J 27:1523–1529PubMedCrossRef Gianni M, Dentali F, Grandi AM et al (2006) Apical ballooning syndrome or takotsubo cardiomyopathy: a systematic review. Eur Heart J 27:1523–1529PubMedCrossRef
24.
Zurück zum Zitat Pilgrim TM, Wyss TR (2008) Takotsubo cardiomyopathy or transient left ventricular apical ballooning syndrome: A systematic review. Int J Cardiol 124:283–292PubMedCrossRef Pilgrim TM, Wyss TR (2008) Takotsubo cardiomyopathy or transient left ventricular apical ballooning syndrome: A systematic review. Int J Cardiol 124:283–292PubMedCrossRef
25.
Zurück zum Zitat Haghi D, Athanasiadis A, Papavassiliu T et al (2006) Right ventricular involvement in Takotsubo cardiomyopathy. Eur Heart J 27:2433–2439PubMedCrossRef Haghi D, Athanasiadis A, Papavassiliu T et al (2006) Right ventricular involvement in Takotsubo cardiomyopathy. Eur Heart J 27:2433–2439PubMedCrossRef
26.
Zurück zum Zitat Sato M, Fujita S, Saito A et al (2006) Increased incidence of transient left ventricular apical ballooning (so-called ‘Takotsubo’ cardiomyopathy) after the mid-Niigata Prefecture earthquake. Circ J 70:947–953PubMedCrossRef Sato M, Fujita S, Saito A et al (2006) Increased incidence of transient left ventricular apical ballooning (so-called ‘Takotsubo’ cardiomyopathy) after the mid-Niigata Prefecture earthquake. Circ J 70:947–953PubMedCrossRef
27.
Zurück zum Zitat Tsuchihashi K, Ueshima K, Uchida T et al (2001) Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina pectoris-myocardial infarction investigations in Japan. J Am Coll Cardiol 38:11–18PubMedCrossRef Tsuchihashi K, Ueshima K, Uchida T et al (2001) Transient left ventricular apical ballooning without coronary artery stenosis: a novel heart syndrome mimicking acute myocardial infarction. Angina pectoris-myocardial infarction investigations in Japan. J Am Coll Cardiol 38:11–18PubMedCrossRef
28.
Zurück zum Zitat Dib C, Asirvatham S, Elesber A et al (2009) Clinical correlates and prognostic significance of electrocardiographic abnormalities in apical ballooning syndrome (Takotsubo/stress-induced cardiomyopathy). Am Heart J 157:933–938PubMedCrossRef Dib C, Asirvatham S, Elesber A et al (2009) Clinical correlates and prognostic significance of electrocardiographic abnormalities in apical ballooning syndrome (Takotsubo/stress-induced cardiomyopathy). Am Heart J 157:933–938PubMedCrossRef
29.
Zurück zum Zitat Sharkey SW, Lesser JR, Menon M et al (2008) Spectrum and significance of electrocardiographic patterns, troponin levels, and thrombolysis in myocardial infarction frame count in patients with stress (tako-tsubo) cardiomyopathy and comparison to those in patients with ST-elevation anterior wall myocardial infarction. Am J Cardiol 101:1723–1728PubMedCrossRef Sharkey SW, Lesser JR, Menon M et al (2008) Spectrum and significance of electrocardiographic patterns, troponin levels, and thrombolysis in myocardial infarction frame count in patients with stress (tako-tsubo) cardiomyopathy and comparison to those in patients with ST-elevation anterior wall myocardial infarction. Am J Cardiol 101:1723–1728PubMedCrossRef
30.
Zurück zum Zitat Bybee KA, Motiei A, Syed IS et al (2007) Electrocardiography cannot reliably differentiate transient left ventricular apical ballooning syndrome from anterior ST-segment elevation myocardial infarction. J Electrocardiol 40:38 e31–e36PubMedCrossRef Bybee KA, Motiei A, Syed IS et al (2007) Electrocardiography cannot reliably differentiate transient left ventricular apical ballooning syndrome from anterior ST-segment elevation myocardial infarction. J Electrocardiol 40:38 e31–e36PubMedCrossRef
31.
Zurück zum Zitat Prasad A, Lerman A, Rihal CS (2008) Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J 155:408–417PubMedCrossRef Prasad A, Lerman A, Rihal CS (2008) Apical ballooning syndrome (Tako-Tsubo or stress cardiomyopathy): a mimic of acute myocardial infarction. Am Heart J 155:408–417PubMedCrossRef
32.
Zurück zum Zitat Madhavan M, Borlaug BA, Lerman A et al (2009) Stress hormone and circulating biomarker profile of apical ballooning syndrome (Takotsubo cardiomyopathy): insights into the clinical significance of B-type natriuretic peptide and troponin levels. Heart 95:1436–1441PubMedCrossRef Madhavan M, Borlaug BA, Lerman A et al (2009) Stress hormone and circulating biomarker profile of apical ballooning syndrome (Takotsubo cardiomyopathy): insights into the clinical significance of B-type natriuretic peptide and troponin levels. Heart 95:1436–1441PubMedCrossRef
33.
Zurück zum Zitat Akashi YJ, Musha H, Nakazawa K, Miyake F (2004) Plasma brain natriuretic peptide in takotsubo cardiomyopathy. QJM 97:599–607PubMedCrossRef Akashi YJ, Musha H, Nakazawa K, Miyake F (2004) Plasma brain natriuretic peptide in takotsubo cardiomyopathy. QJM 97:599–607PubMedCrossRef
34.
Zurück zum Zitat Gaibazzi N, Ugo F, Vignali L et al (2009) Tako-Tsubo cardiomyopathy with coronary artery stenosis: a case-series challenging the original definition. Int J Cardiol 133:205–212PubMedCrossRef Gaibazzi N, Ugo F, Vignali L et al (2009) Tako-Tsubo cardiomyopathy with coronary artery stenosis: a case-series challenging the original definition. Int J Cardiol 133:205–212PubMedCrossRef
35.
Zurück zum Zitat Deetjen AG, Conradi G, Mollmann S et al (2006) Value of gadolinium-enhanced magnetic resonance imaging in patients with Tako-Tsubo-like left ventricular dysfunction. J Cardiovasc Magn Reson 8:367–372PubMedCrossRef Deetjen AG, Conradi G, Mollmann S et al (2006) Value of gadolinium-enhanced magnetic resonance imaging in patients with Tako-Tsubo-like left ventricular dysfunction. J Cardiovasc Magn Reson 8:367–372PubMedCrossRef
36.
Zurück zum Zitat Sharkey SW, Lesser JR, Zenovich AG et al (2005) Acute and reversible cardiomyopathy provoked by stress in women from the United States. Circulation 111:472–479PubMedCrossRef Sharkey SW, Lesser JR, Zenovich AG et al (2005) Acute and reversible cardiomyopathy provoked by stress in women from the United States. Circulation 111:472–479PubMedCrossRef
37.
Zurück zum Zitat Hahn JY, Gwon HC, Park SW et al (2007) The clinical features of transient left ventricular nonapical ballooning syndrome: comparison with apical ballooning syndrome. Am Heart J 154:1166–1173PubMedCrossRef Hahn JY, Gwon HC, Park SW et al (2007) The clinical features of transient left ventricular nonapical ballooning syndrome: comparison with apical ballooning syndrome. Am Heart J 154:1166–1173PubMedCrossRef
38.
Zurück zum Zitat Hurst RT, Askew JW, Reuss CS et al (2006) Transient midventricular ballooning syndrome: a new variant. J Am Coll Cardiol 48:579–583PubMedCrossRef Hurst RT, Askew JW, Reuss CS et al (2006) Transient midventricular ballooning syndrome: a new variant. J Am Coll Cardiol 48:579–583PubMedCrossRef
39.
Zurück zum Zitat Kurowski V, Kaiser A, Hof K von et al (2007) Apical and midventricular transient left ventricular dysfunction syndrome (tako-tsubo cardiomyopathy): frequency, mechanisms, and prognosis. Chest 132:809–816PubMedCrossRef Kurowski V, Kaiser A, Hof K von et al (2007) Apical and midventricular transient left ventricular dysfunction syndrome (tako-tsubo cardiomyopathy): frequency, mechanisms, and prognosis. Chest 132:809–816PubMedCrossRef
40.
Zurück zum Zitat Elesber AA, Prasad A, Bybee KA et al (2006) Transient cardiac apical ballooning syndrome: prevalence and clinical implications of right ventricular involvement. J Am Coll Cardiol 47:1082–1083PubMedCrossRef Elesber AA, Prasad A, Bybee KA et al (2006) Transient cardiac apical ballooning syndrome: prevalence and clinical implications of right ventricular involvement. J Am Coll Cardiol 47:1082–1083PubMedCrossRef
41.
Zurück zum Zitat Lee VH, Connolly HM, Fulgham JR et al (2006) Tako-tsubo cardiomyopathy in aneurysmal subarachnoid hemorrhage: an underappreciated ventricular dysfunction. J Neurosurg 105:264–270PubMedCrossRef Lee VH, Connolly HM, Fulgham JR et al (2006) Tako-tsubo cardiomyopathy in aneurysmal subarachnoid hemorrhage: an underappreciated ventricular dysfunction. J Neurosurg 105:264–270PubMedCrossRef
42.
Zurück zum Zitat Lee VH, Oh JK, Mulvagh SL, Wijdicks EF (2006) Mechanisms in neurogenic stress cardiomyopathy after aneurysmal subarachnoid hemorrhage. Neurocrit Care 5:243–249PubMedCrossRef Lee VH, Oh JK, Mulvagh SL, Wijdicks EF (2006) Mechanisms in neurogenic stress cardiomyopathy after aneurysmal subarachnoid hemorrhage. Neurocrit Care 5:243–249PubMedCrossRef
Metadaten
Titel
Proposed Mayo Clinic criteria for the diagnosis of Tako-Tsubo cardiomyopathy and long-term prognosis
verfasst von
M. Madhavan
A. Prasad, MD
Publikationsdatum
01.06.2010
Verlag
Urban and Vogel
Erschienen in
Herz / Ausgabe 4/2010
Print ISSN: 0340-9937
Elektronische ISSN: 1615-6692
DOI
https://doi.org/10.1007/s00059-010-3339-x

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