Background
Methods
Patients enrollment and sample preparation
First dimension high pH RP chromatography
Second dimension low pH RP chromatography coupled with MS/MS measurement
Protein identification
Bioinformatics
Western blot analysis
Results
No | SwissProt AC | Name protein description | Gene Name | Molecular Weight | experiment 1 | experiment 2 | ||
---|---|---|---|---|---|---|---|---|
Coverage(%) | Matched Peptides number | Coverage(%) | Matched Peptides number | |||||
1 | P43652 | Afamin | AFM | 69,069 | 31.9 | 10 | 35.7 | 10 |
2 | P02763 | Alpha-1-acid glycoprotein 1 | ORM1 | 23,512 | 40.8 | 17 | 40.8 | 15 |
3 | P19652 | Alpha-1-acid glycoprotein 2 | ORM2 | 23,603 | 45.8 | 15 | 53.2 | 15 |
4 | P01011 | Alpha-1-antichymotrypsin | SERPINA3 | 47,651 | 53 | 15 | 44.2 | 16 |
5 | P01009 | Alpha-1-antitrypsin | SERPINA1 | 46,737 | 62.7 | 86 | 64.4 | 76 |
6 | P04217 | Alpha-1B-glycoprotein | A1BG | 54,254 | 39.8 | 17 | 48.5 | 19 |
7 | P08697 | Alpha-2-antiplasmin | SERPINF2 | 54,566 | 29.1 | 9 | 47.1 | 11 |
8 | P02765 | Alpha-2-HS-glycoprotein | AHSG | 39,325 | 42.8 | 14 | 55.9 | 18 |
9 | P01023 | Alpha-2-macroglobulin | A2M | 163,291 | 46.8 | 47 | 47.4 | 46 |
10 | P48728 | Aminomethyltransferase, mitochondrial | AMT | 43,946 | 2.2 | 1 | - | - |
11 | P01019 | Angiotensinogen | AGT | 53,154 | 37.7 | 14 | 25.8 | 11 |
12 | C9JTQ0 | Ankyrin repeat domain-containing protein 63 | ANKRD63 | 39,620 | 15 | 1 | - | - |
13 | P01008 | Antithrombin-III | SERPINC1 | 52,602 | 61.9 | 21 | 54.7 | 24 |
14 | P02647 | Apolipoprotein A-I | APOA1 | 30,778 | 73.8 | 67 | 82.4 | 69 |
15 | P02652 | Apolipoprotein A-II | APOA2 | 11,175 | 70 | 9 | 64 | 9 |
16 | P06727 | Apolipoprotein A-IV | APOA4 | 45,399 | 67.2 | 24 | 63.1 | 25 |
17 | P02654 | Apolipoprotein C-I | APOC1 | 9332 | 26.5 | 3 | 37.4 | 3 |
18 | P02655 | Apolipoprotein C-II | APOC2 | 11,284 | 39.6 | 2 | 50.5 | 3 |
19 | P02656 | Apolipoprotein C-III | APOC3 | 10,852 | 34.3 | 2 | 51.5 | 6 |
20 | P05090 | Apolipoprotein D | APOD | 21,276 | 24.9 | 3 | 28.6 | 3 |
21 | P02649 | Apolipoprotein E | APOE | 36,154 | 43.2 | 6 | 43.5 | 4 |
22 | Q13790 | Apolipoprotein F | APOF | 35,399 | - | - | 8 | 1 |
23 | O95445 | Apolipoprotein M | APOM | 21,253 | 26.6 | 2 | 30.3 | 2 |
24 | Q9H2U1 | ATP-dependent RNA helicase DHX36 | DHX36 | 114,760 | - | - | 17.9 | 1 |
25 | O75882 | Attractin | ATRN | 158,537 | 15 | 1 | - | - |
26 | P98160 | Basement membrane-specific heparan sulfate proteoglycan core protein | HSPG2 | 468,830 | 30.8 | 43 | 31 | 46 |
27 | P02749 | Beta-2-glycoprotein 1 | APOH | 38,298 | 51 | 15 | 41.5 | 16 |
28 | Q96KN2 | Beta-Ala-His dipeptidase | CNDP1 | 56,706 | 18.9 | 1 | - | - |
29 | P43251 | Biotinidase | BTD | 61,133 | 9.2 | 2 | 14.2 | 1 |
30 | Q7L273 | BTB/POZ domain-containing protein KCTD9 | KCTD9 | 42,567 | - | - | 30.1 | 1 |
31 | P04003 | C4b-binding protein alpha chain | C4BPA | 67,033 | 11.9 | 2 | 27 | 4 |
32 | Q96IY4 | Carboxypeptidase B2 | CPB2 | 48,424 | 13 | 2 | 16.1 | 2 |
33 | P22792 | Carboxypeptidase N subunit 2 | CPN2 | 60,557 | - | - | 10.8 | 2 |
34 | Q9ULM6 | CCR4-NOT transcription complex subunit 6 | CNOT6 | 63,307 | - | - | 2.3 | 1 |
35 | Q8N8E3 | Centrosomal protein of 112 kDa | CEP112 | 112,749 | 17.4 | 1 | - | - |
36 | Q5SW79 | Centrosomal protein of 170 kDa | CEP170 | 175,293 | - | - | 5.9 | 1 |
37 | P00450 | Ceruloplasmin | CP | 122,205 | 59.6 | 47 | 58.1 | 58 |
38 | O14647 | Chromodomain-helicase-DNA-binding protein 2 | CHD2 | 211,344 | - | - | 12 | 1 |
39 | P10909 | Clusterin | CLU | 52,495 | 41.4 | 14 | 50.1 | 12 |
40 | P00740 | Coagulation factor IX | F9 | 51,778 | 15.2 | 1 | - | - |
41 | P00742 | Coagulation factor X | F10 | 54,732 | 24.6 | 1 | 14.1 | 1 |
42 | P00748 | Coagulation factor XII | F12 | 67,792 | 29.9 | 4 | 20.8 | 4 |
43 | Q5TID7 | Coiled-coil domain-containing protein 181 | CCDC181 | 60,103 | - | - | 7.9 | 1 |
44 | P02746 | Complement C1q subcomponent subunit B | C1QB | 26,722 | 20.2 | 1 | 18.6 | 1 |
45 | Q9NZP8 | Complement C1r subcomponent-like protein | C1RL | 53,498 | 8.6 | 1 | 6.2 | 1 |
46 | P06681 | Complement C2 | C2 | 83,268 | 21.5 | 4 | 22.7 | 6 |
47 | P01024 | Complement C3 | C3 | 187,148 | 67.1 | 121 | 74.1 | 119 |
48 | P0C0L4 | Complement C4-A | C4A | 192,785 | 46.6 | 53 | 54.8 | 66 |
49 | P0C0L5 | Complement C4-B | C4B | 192,751 | 46.3 | 52 | 53 | 66 |
50 | P01031 | Complement C5 | C5 | 188,305 | 20.3 | 7 | 27.1 | 12 |
51 | P13671 | Complement component C6 | C6 | 104,786 | 26 | 6 | 25.5 | 6 |
52 | P10643 | Complement component C7 | C7 | 93,518 | 35.2 | 8 | 23.1 | 5 |
53 | P07357 | Complement component C8 alpha chain | C8A | 65,163 | 24.8 | 5 | 23.5 | 4 |
54 | P07358 | Complement component C8 beta chain | C8B | 67,047 | 37.1 | 4 | 37.2 | 6 |
55 | P07360 | Complement component C8 gamma chain | C8G | 22,277 | 48.5 | 7 | 48 | 5 |
56 | P02748 | Complement component C9 | C9 | 63,173 | 36.5 | 8 | 35.8 | 10 |
57 | P00751 | Complement factor B | CFB | 85,533 | 41.4 | 20 | 51.4 | 25 |
58 | P08603 | Complement factor H | CFH | 139,096 | 55.4 | 43 | 56.9 | 45 |
59 | Q03591 | Complement factor H-related protein 1 | CFHR1 | 37,651 | 33.9 | 2 | 27.3 | 5 |
60 | P05156 | Complement factor I | CFI | 65,750 | 31.1 | 7 | 31.7 | 5 |
61 | P08185 | Corticosteroid-binding globulin | SERPINA6 | 45,141 | 19.5 | 3 | 17.3 | 2 |
62 | Q9UBG0 | C-type mannose receptor 2 | MRC2 | 166,674 | 3.2 | 1 | - | - |
63 | P01034 | Cystatin-C | CST3 | 15,799 | 22.6 | 1 | - | - |
64 | P30876 | DNA-directed RNA polymerase II subunit RPB2 | POLR2B | 133,897 | - | - | 10.7 | 1 |
65 | Q8NHS0 | DnaJ homolog subfamily B member 8 | DNAJB8 | 25,686 | 16.8 | 1 | - | - |
66 | Q96DT5 | Dynein heavy chain 11, axonemal | DNAH11 | 520,369 | - | - | 9.8 | 1 |
67 | Q9C0C9 | E2 ubiquitin-conjugating enzyme | UBE2O | 141,293 | - | - | 3.9 | 1 |
68 | O95071 | E3 ubiquitin-protein ligase UBR5 | UBR5 | 309,352 | 7.6 | 1 | - | - |
69 | A4FU69 | EF-hand calcium-binding domain-containing protein 5 | EFCAB5 | 173,404 | 8.1 | 1 | - | - |
70 | Q16610 | Extracellular matrix protein 1 | ECM1 | 60,674 | 20.7 | 2 | 11.5 | 2 |
71 | Q9UGM5 | Fetuin-B | FETUB | 42,055 | 12.8 | 1 | 18.3 | 1 |
72 | P02671 | Fibrinogen alpha chain | FGA | 94,973 | 44.8 | 40 | 47.6 | 44 |
73 | P02675 | Fibrinogen beta chain | FGB | 55,928 | 72.1 | 53 | 68.6 | 42 |
74 | P02679 | Fibrinogen gamma chain | FGG | 51,512 | 69.1 | 36 | 68 | 34 |
75 | P02751 | Fibronectin | FN1 | 262,625 | 30.3 | 33 | 31.2 | 34 |
76 | Q08380 | Galectin-3-binding protein | LGALS3BP | 65,331 | 22.9 | 1 | 28.7 | 4 |
77 | P06396 | Gelsolin | GSN | 85,698 | 43.9 | 16 | 43.6 | 20 |
78 | P07093 | Glia-derived nexin | SERPINE2 | 44,002 | 34.7 | 4 | 28.6 | 3 |
79 | P22352 | Glutathione peroxidase 3 | GPX3 | 25,552 | 16.4 | 2 | 27 | 1 |
80 | Q7Z4J2 | Glycosyltransferase 6 domain-containing protein 1 | GLT6D1 | 36,274 | 2.6 | 1 | - | - |
81 | P0CG08 | Golgi pH regulator B | GPR89B | 52,917 | - | - | 7.7 | 1 |
82 | P00738 | Haptoglobin | HP | 45,205 | 61.1 | 26 | 58.6 | 23 |
83 | P00739 | Haptoglobin-related protein | HPR | 39,030 | 44.3 | 10 | - | - |
84 | Q9Y6N9 | Harmonin | USH1C | 62,211 | 7.8 | 1 | - | - |
85 | P69905 | Hemoglobin subunit alpha | HBA1/HBA2 | 15,258 | - | - | 28.2 | 1 |
86 | P68871 | Hemoglobin subunit beta | HBB | 15,998 | 43.5 | 2 | 52.4 | 1 |
87 | P02790 | Hemopexin | HPX | 51,676 | 55.8 | 44 | 76.4 | 50 |
88 | P05546 | Heparin cofactor 2 | SERPIND1 | 57,071 | 21 | 6 | 34.9 | 6 |
89 | Q04756 | Hepatocyte growth factor activator | HGFAC | 70,682 | 5.3 | 1 | - | - |
90 | P04196 | Histidine-rich glycoprotein | HRG | 59,578 | 33 | 15 | 37.9 | 18 |
91 | O43365 | Homeobox protein Hox-A3 | HOXA3 | 46,369 | 6.5 | 1 | - | - |
92 | P78426 | Homeobox protein Nkx-6.1 | NKX6–1 | 37,849 | 16.4 | 1 | - | - |
93 | Q14520 | Hyaluronan-binding protein 2 | HABP2 | 62,672 | 15.4 | 2 | 11.8 | 3 |
94 | P0DOX2 | Immunoglobulin alpha-2 heavy chain | N/A | 48,935 | 39.1 | 14 | 40.9 | 12 |
95 | P0DOX3 | Immunoglobulin delta heavy chain | N/A | 56,224 | 19.9 | 1 | 23.4 | 1 |
96 | P0DOX4 | Immunoglobulin epsilon heavy chain | N/A | 60,323 | 8.4 | 2 | 15.7 | 2 |
97 | P0DOX5 | Immunoglobulin gamma-1 heavy chain | N/A | 49,330 | 70.6 | 144 | 71.9 | 123 |
98 | P01876 | Immunoglobulin heavy constant alpha 1 | IGHA1 | 37,655 | 42.8 | 23 | 48.2 | 16 |
99 | P01859 | Immunoglobulin heavy constant gamma 2 | IGHG2 | 35,901 | 74.9 | 104 | 69.9 | 92 |
100 | P01860 | Immunoglobulin heavy constant gamma 3 | IGHG3 | 41,287 | 72.4 | 69 | 78.3 | 65 |
101 | P01861 | Immunoglobulin heavy constant gamma 4 | IGHG4 | 35,941 | 79.8 | 101 | 68.8 | 85 |
102 | P01871 | Immunoglobulin heavy constant mu | IGHM | 49,440 | 33.1 | 10 | 34.7 | 12 |
103 | A0A0C4DH31 | Immunoglobulin heavy variable 1–18 | IGHV1–18 | 12,820 | 53 | 7 | 48.7 | 9 |
104 | P23083 | Immunoglobulin heavy variable 1–2 | IGHV1–2 | 13,085 | 47.9 | 6 | - | - |
105 | A0A0C4DH33 | Immunoglobulin heavy variable 1–24 | IGHV1–24 | 12,824 | 38.5 | 2 | 38.5 | 3 |
106 | A0A0C4DH29 | Immunoglobulin heavy variable 1–3 | IGHV1–3 | 13,008 | 38.5 | 3 | - | - |
107 | A0A0A0MS14 | Immunoglobulin heavy variable 1–45 | IGHV1–45 | 13,508 | 9.4 | 2 | - | - |
108 | P01743 | Immunoglobulin heavy variable 1–46 | IGHV1–46 | 12,933 | - | - | 32.5 | 5 |
109 | P01742 | Immunoglobulin heavy variable 1–69 | IGHV1–69 | 12,659 | - | - | 34.2 | 5 |
110 | P01762 | Immunoglobulin heavy variable 3–11 | IGHV3–11 | 12,909 | 38.5 | 10 | 53.9 | 11 |
111 | P01766 | Immunoglobulin heavy variable 3–13 | IGHV3–13 | 12,506 | 60.3 | 6 | - | - |
112 | A0A0B4J1V0 | Immunoglobulin heavy variable 3–15 | IGHV3–15 | 12,926 | 55.5 | 8 | 42.9 | 7 |
113 | P01764 | Immunoglobulin heavy variable 3–23 | IGHV3–23 | 12,582 | 60.7 | 15 | 54.7 | 10 |
114 | A0A0B4J1X8 | Immunoglobulin heavy variable 3–43 | IGHV3–43 | 13,077 | - | - | 34.8 | 6 |
115 | A0A0A0MS15 | Immunoglobulin heavy variable 3–49 | IGHV3–49 | 13,056 | 47.1 | 3 | 50.4 | 3 |
116 | A0A075B6Q5 | Immunoglobulin heavy variable 3–64 | IGHV3–64 | 12,891 | 59.3 | 2 | 18.6 | 1 |
117 | A0A0C4DH42 | Immunoglobulin heavy variable 3–66 | IGHV3–66 | 12,698 | 61.2 | 14 | 55.2 | 10 |
118 | P01780 | Immunoglobulin heavy variable 3–7 | IGHV3–7 | 12,943 | 76.9 | 14 | 77.8 | 12 |
119 | A0A0B4J1Y9 | Immunoglobulin heavy variable 3–72 | IGHV3–72 | 13,203 | 55.5 | 9 | - | - |
120 | A0A0B4J1V6 | Immunoglobulin heavy variable 3–73 | IGHV3–73 | 12,858 | 58 | 3 | 58 | 4 |
121 | P01782 | Immunoglobulin heavy variable 3–9 | IGHV3–9 | 12,945 | 51.7 | 8 | 51.7 | 9 |
122 | P06331 | Immunoglobulin heavy variable 4–34 | IGHV4–34 | 13,815 | - | - | 38.2 | 4 |
123 | P01824 | Immunoglobulin heavy variable 4–39 | IGHV4–39 | 13,917 | 19.2 | 4 | - | - |
124 | A0A0C4DH38 | Immunoglobulin heavy variable 5–51 | IGHV5–51 | 12,675 | 66.7 | 9 | 50.4 | 8 |
125 | P01834 | Immunoglobulin kappa constant | IGKC | 11,765 | 88.8 | 50 | 92.5 | 37 |
126 | P0DOX7 | Immunoglobulin kappa light chain | N/A | 23,379 | 61.2 | 52 | 62.6 | 39 |
127 | P04430 | Immunoglobulin kappa variable 1–16 | IGKV1–16 | 12,618 | - | - | 34.2 | 2 |
128 | A0A075B6S5 | Immunoglobulin kappa variable 1–27 | IGKV1–27 | 12,712 | 47 | 8 | 65 | 8 |
129 | P01594 | Immunoglobulin kappa variable 1–33 | IGKV1–33 | 12,848 | 49.6 | 5 | 42.7 | 4 |
130 | P01602 | Immunoglobulin kappa variable 1–5 | IGKV1–5 | 12,782 | 30.8 | 3 | 30.8 | 6 |
131 | A0A0C4DH72 | Immunoglobulin kappa variable 1–6 | IGKV1–6 | 12,697 | 47 | 4 | 47 | 5 |
132 | A0A0C4DH69 | Immunoglobulin kappa variable 1–9 | IGKV1–9 | 12,715 | 74.4 | 5 | 44.4 | 5 |
133 | P01611 | Immunoglobulin kappa variable 1D-12 | IGKV1D-12 | 12,620 | 44.4 | 5 | 49.6 | 7 |
134 | A0A0B4J2D9 | Immunoglobulin kappa variable 1D-13 | IGKV1D-13 | 12,569 | 13.7 | 1 | - | - |
135 | A0A075B6S4 | Immunoglobulin kappa variable 1D-17 | IGKV1D-17 | 12,835 | 28.2 | 1 | 43.6 | 2 |
136 | P04432 | Immunoglobulin kappa variable 1D-39 | IGKV1D-39 | 12,737 | 47 | 6 | 47.9 | 6 |
137 | P06310 | Immunoglobulin kappa variable 2–30 | IGKV2–30 | 13,185 | 50 | 5 | 63.3 | 7 |
138 | P01615 | Immunoglobulin kappa variable 2D-28 | IGKV2D-28 | 12,957 | 33.3 | 5 | 40.8 | 5 |
139 | A0A075B6S2 | Immunoglobulin kappa variable 2D-29 | IGKV2D-29 | 13,143 | - | - | 20.8 | 5 |
140 | P01614 | Immunoglobulin kappa variable 2D-40 | IGKV2D-40 | 13,310 | 37.2 | 6 | 37.2 | 5 |
141 | P04433 | Immunoglobulin kappa variable 3–11 | IGKV3–11 | 12,575 | 54.8 | 16 | 49.6 | 10 |
142 | P01624 | Immunoglobulin kappa variable 3–15 | IGKV3–15 | 12,496 | 42.6 | 9 | 50.4 | 8 |
143 | P01619 | Immunoglobulin kappa variable 3–20 | IGKV3–20 | 12,557 | 70.7 | 16 | 70.7 | 14 |
144 | A0A087WSY6 | Immunoglobulin kappa variable 3D-15 | IGKV3D-15 | 12,534 | 42.6 | 10 | 56.5 | 8 |
145 | A0A0C4DH25 | Immunoglobulin kappa variable 3D-20 | IGKV3D-20 | 12,515 | 64.7 | 10 | 64.7 | 8 |
146 | P06312 | Immunoglobulin kappa variable 4–1 | IGKV4–1 | 13,380 | 34.7 | 10 | 40.5 | 6 |
147 | A0M8Q6 | Immunoglobulin lambda constant 7 | IGLC7 | 11,254 | 54.7 | 13 | 53.8 | 10 |
148 | A0A0B4J1U3 | Immunoglobulin lambda variable 1–36 | IGLV1–36 | 12,478 | 13.7 | 1 | 13.7 | 1 |
149 | P01703 | Immunoglobulin lambda variable 1–40 | IGLV1–40 | 12,302 | 21.2 | 2 | - | - |
150 | P01700 | Immunoglobulin lambda variable 1–47 | IGLV1–47 | 12,284 | 54.7 | 4 | 39.3 | 3 |
151 | P01706 | Immunoglobulin lambda variable 2–11 | IGLV2–11 | 12,644 | 22.7 | 3 | - | - |
152 | A0A075B6K4 | Immunoglobulin lambda variable 3–10 | IGLV3–10 | 12,441 | 40 | 4 | 40 | 3 |
153 | P01714 | Immunoglobulin lambda variable 3–19 | IGLV3–19 | 12,042 | 50 | 2 | 42.9 | 1 |
154 | P80748 | Immunoglobulin lambda variable 3–21 | IGLV3–21 | 12,446 | 35.9 | 3 | - | - |
155 | P01717 | Immunoglobulin lambda variable 3–25 | IGLV3–25 | 12,011 | - | - | 43.8 | 3 |
156 | P01721 | Immunoglobulin lambda variable 6–57 | IGLV6–57 | 12,566 | 20.5 | 2 | - | - |
157 | P0DOX8 | Immunoglobulin lambda-1 light chain | N/A | 22,830 | 44.4 | 23 | 44.4 | 20 |
158 | P15814 | Immunoglobulin lambda-like polypeptide 1 | IGLL1 | 22,963 | 23 | 5 | 23 | 5 |
159 | P35858 | Insulin-like growth factor-binding protein complex acid labile subunit | IGFALS | 66,035 | 23.1 | 4 | 27.4 | 6 |
160 | P16144 | Integrin beta-4 | ITGB4 | 202,167 | 4.9 | 1 | - | - |
161 | P19827 | Inter-alpha-trypsin inhibitor heavy chain H1 | ITIH1 | 101,389 | 33.6 | 20 | 33.7 | 25 |
162 | P19823 | Inter-alpha-trypsin inhibitor heavy chain H2 | ITIH2 | 106,463 | 35.9 | 18 | 42.6 | 20 |
163 | Q06033 | Inter-alpha-trypsin inhibitor heavy chain H3 | ITIH3 | 99,849 | 5.2 | 1 | 15.5 | 1 |
164 | Q14624 | Inter-alpha-trypsin inhibitor heavy chain H4 | ITIH4 | 103,357 | 38.4 | 23 | 47 | 26 |
165 | Q15811 | Intersectin-1 | ITSN1 | 195,422 | - | - | 9.9 | 1 |
166 | P29622 | Kallistatin | SERPINA4 | 48,542 | 26.5 | 4 | 23 | 5 |
167 | Q92764 | Keratin, type I cuticular Ha5 | KRT35 | 50,361 | - | - | 16.7 | 1 |
168 | P13645 | Keratin, type I cytoskeletal 10 | KRT10 | 58,827 | 5.8 | 1 | - | - |
169 | P04264 | Keratin, type II cytoskeletal 1 | KRT1 | 66,039 | 23.6 | 3 | 30 | 2 |
170 | P01042 | Kininogen-1 | KNG1 | 71,957 | 53.7 | 25 | 41 | 23 |
171 | P02750 | Leucine-rich alpha-2-glycoprotein | LRG1 | 38,178 | 21.6 | 4 | 27.1 | 5 |
172 | P18428 | Lipopolysaccharide-binding protein | LBP | 53,384 | 14.8 | 1 | 13.3 | 1 |
173 | P51884 | Lumican | LUM | 38,429 | 30.2 | 3 | 27.8 | 3 |
174 | P14174 | Macrophage migration inhibitory factor | MIF | 12,476 | 18.3 | 2 | - | - |
175 | P01033 | Metalloproteinase inhibitor 1 | TIMP1 | 23,171 | 18.8 | 2 | 34.8 | 2 |
176 | Q7Z5P9 | Mucin-19 | MUC19 | 805,253 | 4.3 | 1 | - | - |
177 | P35579 | Myosin-9 | MYH9 | 226,532 | - | - | 15.8 | 1 |
178 | Q96PD5 | N-acetylmuramoyl-L-alanine amidase | PGLYRP2 | 62,217 | 26 | 7 | 29.3 | 6 |
179 | A6NHN0 | Otolin-1 | OTOL1 | 49,422 | 15.3 | 1 | - | - |
180 | P04180 | Phosphatidylcholine-sterol acyltransferase | LCAT | 49,578 | 15.5 | 2 | - | - |
181 | P36955 | Pigment epithelium-derived factor | SERPINF1 | 46,312 | 22.3 | 5 | 17.9 | 5 |
182 | P03952 | Plasma kallikrein | KLKB1 | 71,370 | 23 | 6 | 26.5 | 6 |
183 | P05155 | Plasma protease C1 inhibitor | SERPING1 | 55,154 | 34.8 | 9 | 33.2 | 16 |
184 | P05154 | Plasma serine protease inhibitor | SERPINA5 | 45,675 | 13.6 | 3 | - | - |
185 | P00747 | Plasminogen | PLG | 90,569 | 63 | 30 | 58.8 | 32 |
186 | Q96GD3 | Polycomb protein SCMH1 | SCMH1 | 73,354 | 4.7 | 1 | - | - |
187 | Q8WUM4 | Programmed cell death 6-interacting protein | PDCD6IP | 96,023 | - | - | 14.1 | 1 |
188 | P46013 | Proliferation marker protein Ki-67 | MKI67 | 358,694 | 11.9 | 1 | 21.8 | 1 |
189 | P15309 | Prostatic acid phosphatase | ACPP | 44,566 | 25.1 | 4 | 17.9 | 2 |
190 | P02760 | Protein AMBP | AMBP | 38,999 | 38.9 | 11 | 42.1 | 12 |
191 | Q9UK55 | Protein Z-dependent protease inhibitor | SERPINA10 | 50,707 | 15.5 | 2 | 18.9 | 2 |
192 | Q96PF1 | Protein-glutamine gamma-glutamyltransferase Z | TGM7 | 79,941 | - | - | 7.5 | 1 |
193 | P00734 | Prothrombin | F2 | 70,037 | 59.8 | 33 | 62.4 | 31 |
194 | P02753 | Retinol-binding protein 4 | RBP4 | 23,010 | 40.3 | 11 | 55.7 | 13 |
195 | O94885 | SAM and SH3 domain-containing protein 1 | SASH1 | 136,653 | - | - | 10.3 | 1 |
196 | P04279 | Semenogelin-1 | SEMG1 | 52,131 | 30.5 | 5 | 32.3 | 5 |
197 | Q02383 | Semenogelin-2 | SEMG2 | 65,444 | 21 | 3 | 18 | 5 |
198 | P57059 | Serine/threonine-protein kinase SIK1 | SIK1 | 84,902 | - | - | 7.3 | 1 |
199 | P02787 | Serotransferrin | TF | 77,064 | 71.4 | 143 | 79.4 | 185 |
200 | P02768 | Serum albumin | ALB | 69,367 | 89.3 | 607 | 91.3 | 550 |
201 | P35542 | Serum amyloid A-4 protein | SAA4 | 14,747 | 30 | 2 | 49.2 | 6 |
202 | P02743 | Serum amyloid P-component | APCS | 25,387 | 26.5 | 5 | 25.1 | 5 |
203 | P27169 | Serum paraoxonase/arylesterase 1 | PON1 | 39,731 | 24.5 | 7 | 19.2 | 5 |
204 | P04278 | Sex hormone-binding globulin | SHBG | 43,779 | 18.7 | 4 | 21.9 | 3 |
205 | P09486 | SPARC | SPARC | 34,632 | - | - | 5.3 | 1 |
206 | Q6N022 | Teneurin-4 | TENM4 | 307,957 | 5.3 | 1 | - | - |
207 | P05452 | Tetranectin | CLEC3B | 22,537 | 22.8 | 2 | 30.2 | 2 |
208 | P05543 | Thyroxine-binding globulin | SERPINA7 | 46,325 | 14.5 | 1 | 23.6 | 2 |
209 | Q8WZ42 | Titin | TTN | 3,816,030 | 10.6 | 1 | - | - |
210 | P21675 | Transcription initiation factor TFIID subunit 1 | TAF1 | 212,677 | - | - | 7 | 1 |
211 | Q66K66 | Transmembrane protein 198 | TMEM198 | 39,475 | 2.5 | 2 | 2.5 | 1 |
212 | P02766 | Transthyretin | TTR | 15,887 | 69.4 | 12 | 69.4 | 19 |
213 | P13611 | Versican core protein | VCAN | 372,820 | - | - | 5.2 | 2 |
214 | P02774 | Vitamin D-binding protein | GC | 52,964 | 63.9 | 29 | 60.3 | 28 |
215 | P04070 | Vitamin K-dependent protein C | PROC | 52,071 | - | - | 2.2 | 1 |
216 | P07225 | Vitamin K-dependent protein S | PROS1 | 75,123 | 12.6 | 2 | - | - |
217 | P04004 | Vitronectin | VTN | 54,306 | 32.6 | 11 | 32.2 | 15 |
218 | Q6PF04 | Zinc finger protein 613 | ZNF613 | 70,143 | 6.6 | 1 | - | - |
219 | P25311 | Zinc-alpha-2-glycoprotein | AZGP1 | 34,259 | 52.7 | 14 | 52 | 17 |