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01.12.2012 | Case report | Ausgabe 1/2012 Open Access

Journal of Medical Case Reports 1/2012

Pseudotumoral tracheobronchial amyloidosis mimicking asthma: a case report

Journal of Medical Case Reports > Ausgabe 1/2012
Mounia Serraj, Imane Kamaoui, Kawtar Znati, Salma Kouara, Ferdaous Sahnoune, Bouchra Amara, Mohammed El Biaze, Siham Tizniti, Afaf Amarti, Mohammed Chakib Benjelloun
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1752-1947-6-40) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors' contributions

MS conceptualized the case study, gathered the data and wrote the manuscript. IK interpreted the data, performed the radiology and revised the manuscript. KZ and AA performed the histological evaluation and interpretation of the data. SK and FS acquired the data. BA, MB, ST and MCB gave final approval for publication. All authors read and approved the final manuscript.



Tracheobronchial amyloidosis is an uncommon localized form of amyloidosis that can simulate a tracheal tumor. Clinical signs are not specific and the diagnosis is rarely given before performing a bronchoscopy with multiples biopsies.

Case presentation

We report the case of a 60-year-old Moroccan woman, complaining of dyspnea and wheezing for three years, who was treated at our institution for management of severe asthma. A bronchoscopy revealed a tumor formation of her trachea; multiples biopsies were performed and a diagnosis made of amyloid light-chain amyloidosis. She successfully received an endoscopic resection.


This case highlights the importance of routinely carrying out an endoscopy in any patient complaining of atypical bronchial symptoms or with uncontrolled asthma. Tracheal amyloidosis is a rare disease, confirmed by histological examination of bronchial biopsies, and the treatment of choice is based on the bronchoscopic resection.

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