Skip to main content
Erschienen in: Die Kardiologie 5/2023

06.07.2023 | Pulmonale Hypertonie | Positionspapiere

„Erwachsene mit angeborenen Herzfehlern“: Aktuelle Herausforderung in der medizinischen Versorgung Teil II: Infektiöse Endokarditis, pulmonale Hypertonie, Aortopathien, herzchirurgische Aspekte, Psychokardiologie, ungelöste Probleme und Zukunftsaspekte

Positionspapier der Deutschen Gesellschaft für Kardiologie

verfasst von: Prof. Dr. Dr. Harald Kaemmerer, Stephan Baldus, Helmut Baumgartner, Felix Berger, Fokko de Haan, Stefan Frantz, Dirk Loßnitzer, Anselm Uebing, Corinna Lebherz, Michael Weyand, Gerhard Paul Diller

Erschienen in: Die Kardiologie | Ausgabe 5/2023

Einloggen, um Zugang zu erhalten

Zusammenfassung

Trotz relevanter Rest- und Folgezustände wird die Nachsorge von Erwachsenen mit angeborenen Herzfehlern (EMAH) allzu oft nicht von/bei spezialisierten und/oder zertifizierten Ärzten oder Zentren durchgeführt, obwohl sich im Langzeitverlauf erhebliche Probleme entwickeln können. Zu den wichtigsten Problemkonstellationen neben herzfehlerspezifischen Residuen, der Herzinsuffizienz und Herzrhythmusstörungen gehören die infektiöse Endokarditis, pulmonale Gefäßerkrankungen und pulmonale Hypertonie sowie Aortopathien. Hinzu treten kardiale und nichtkardiale Komorbiditäten, psychische Belastungen einschließend. Das vorliegende Positionspapier der Deutschen Gesellschaft für Kardiologie gibt aktuelle Erläuterungen zu diesen Problemkreisen und unterstreicht die dringende Notwendigkeit einer erfahrenen Nachsorge durch spezialisierte Ärzte oder Kliniken, da Behandlungsschemata von erworbenen Herzerkrankungen nicht unbedingt auf AHF übertragen werden können. Darüber hinaus wird die Notwendigkeit einer primären und sekundären medizinischen Prävention unterstrichen, um die Krankheitslast sowie die sozioökonomische Belastung und die Kosten in dieser besonderen Patientengruppe zu verringern.
Literatur
1.
Zurück zum Zitat Kuijpers JM, Koolbergen DR, Groenink M, Peels KCH, Reichert CLA, Post MC et al (2017) Incidence, risk factors, and predictors of infective endocarditis in adult congenital heart disease: focus on the use of prosthetic material. Eur Heart J 38(26):2048–2056 PubMed Kuijpers JM, Koolbergen DR, Groenink M, Peels KCH, Reichert CLA, Post MC et al (2017) Incidence, risk factors, and predictors of infective endocarditis in adult congenital heart disease: focus on the use of prosthetic material. Eur Heart J 38(26):2048–2056 PubMed
2.
Zurück zum Zitat Tutarel O, Alonso-Gonzalez R, Montanaro C, Schiff R, Uribarri A, Kempny A et al (2018) Infective endocarditis in adults with congenital heart disease remains a lethal disease. Heart 104(2):161–165 PubMedCrossRef Tutarel O, Alonso-Gonzalez R, Montanaro C, Schiff R, Uribarri A, Kempny A et al (2018) Infective endocarditis in adults with congenital heart disease remains a lethal disease. Heart 104(2):161–165 PubMedCrossRef
3.
Zurück zum Zitat Philip M, Tessonier L, Mancini J, Mainardi JL, Fernandez-Gerlinger MP, Lussato D et al (2020) Comparison between ESC and duke criteria for the diagnosis of prosthetic valve infective endocarditis. JACC Cardiovasc Imaging 13(12):2605–2615 PubMedCrossRef Philip M, Tessonier L, Mancini J, Mainardi JL, Fernandez-Gerlinger MP, Lussato D et al (2020) Comparison between ESC and duke criteria for the diagnosis of prosthetic valve infective endocarditis. JACC Cardiovasc Imaging 13(12):2605–2615 PubMedCrossRef
4.
Zurück zum Zitat Ishikita A, Sakamoto I, Yamamura K, Umemoto S, Nagata H, Kitamura Y et al (2021) Usefulness of (18)F-Fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis of infective endocarditis in patients with adult congenital heart disease. Circ J 85(9):1505–1513 PubMedCrossRef Ishikita A, Sakamoto I, Yamamura K, Umemoto S, Nagata H, Kitamura Y et al (2021) Usefulness of (18)F-Fluorodeoxyglucose positron emission tomography/computed tomography in the diagnosis of infective endocarditis in patients with adult congenital heart disease. Circ J 85(9):1505–1513 PubMedCrossRef
5.
Zurück zum Zitat Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F et al (2015) 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J 36(44):3075–3128 PubMedCrossRef Habib G, Lancellotti P, Antunes MJ, Bongiorni MG, Casalta JP, Del Zotti F et al (2015) 2015 ESC Guidelines for the management of infective endocarditis: The Task Force for the Management of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). Eur Heart J 36(44):3075–3128 PubMedCrossRef
6.
Zurück zum Zitat Habib G, Hoen B, Tornos P, Thuny F, Prendergast B, Vilacosta I et al (2009) Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J 30(19):2369–2413 PubMedCrossRef Habib G, Hoen B, Tornos P, Thuny F, Prendergast B, Vilacosta I et al (2009) Guidelines on the prevention, diagnosis, and treatment of infective endocarditis (new version 2009): the Task Force on the Prevention, Diagnosis, and Treatment of Infective Endocarditis of the European Society of Cardiology (ESC). Endorsed by the European Society of Clinical Microbiology and Infectious Diseases (ESCMID) and the International Society of Chemotherapy (ISC) for Infection and Cancer. Eur Heart J 30(19):2369–2413 PubMedCrossRef
7.
Zurück zum Zitat Naber C, Al-Nawas B, Baumgartner H, Becker H‑J, Block M, Erbel R, Ertl G, Franzen D, Gohlke-Bärwolf C, Gattringer R, Graninger W, Handrick W, Heying R, Horstkotte D, Jaussi A, Kern P, Kramer H‑H, Kühl S, Lepper PM, Leyh RG, Lode H, Mehlhorn U, Moreillon P, Mügge A, Mutters R, Peters G, Rosenhek R, Schmaltz AA, Seifert H, Shah PM, Sitter H, Wagner W, Wahl G, Werdan K, Zuber M (2007) Prophylaxe der infektiösen Endokarditis. Kardiologe 1:243–250 CrossRef Naber C, Al-Nawas B, Baumgartner H, Becker H‑J, Block M, Erbel R, Ertl G, Franzen D, Gohlke-Bärwolf C, Gattringer R, Graninger W, Handrick W, Heying R, Horstkotte D, Jaussi A, Kern P, Kramer H‑H, Kühl S, Lepper PM, Leyh RG, Lode H, Mehlhorn U, Moreillon P, Mügge A, Mutters R, Peters G, Rosenhek R, Schmaltz AA, Seifert H, Shah PM, Sitter H, Wagner W, Wahl G, Werdan K, Zuber M (2007) Prophylaxe der infektiösen Endokarditis. Kardiologe 1:243–250 CrossRef
8.
Zurück zum Zitat Muller N, Breuer J, Adler K, Freudenthal NJ (2021) “Body modification: piercing and tattooing in congenital heart disease patients”, decoration or disaster?—a narrative review. Cardiovasc Diagn Ther 11(6):1395–1402 PubMedPubMedCentralCrossRef Muller N, Breuer J, Adler K, Freudenthal NJ (2021) “Body modification: piercing and tattooing in congenital heart disease patients”, decoration or disaster?—a narrative review. Cardiovasc Diagn Ther 11(6):1395–1402 PubMedPubMedCentralCrossRef
9.
Zurück zum Zitat Stammnitz C, Huscher D, Bauer UMM, Urban A, Nordmeyer J, Schubert S et al (2022) Nationwide registry-based analysis of infective endocarditis risk after pulmonary valve replacement. J Am Heart Assoc 11(5):e22231 PubMedPubMedCentralCrossRef Stammnitz C, Huscher D, Bauer UMM, Urban A, Nordmeyer J, Schubert S et al (2022) Nationwide registry-based analysis of infective endocarditis risk after pulmonary valve replacement. J Am Heart Assoc 11(5):e22231 PubMedPubMedCentralCrossRef
10.
Zurück zum Zitat McElhinney DB, Zhang Y, Aboulhosn JA, Morray BH, Biernacka EK, Qureshi AM et al (2021) Multicenter study of Endocarditis after transcatheter pulmonary valve replacement. J Am Coll Cardiol 78(6):575–589 PubMedCrossRef McElhinney DB, Zhang Y, Aboulhosn JA, Morray BH, Biernacka EK, Qureshi AM et al (2021) Multicenter study of Endocarditis after transcatheter pulmonary valve replacement. J Am Coll Cardiol 78(6):575–589 PubMedCrossRef
11.
Zurück zum Zitat Duval X, Alla F, Hoen B, Danielou F, Larrieu S, Delahaye F et al (2006) Estimated risk of endocarditis in adults with predisposing cardiac conditions undergoing dental procedures with or without antibiotic prophylaxis. Clin Infect Dis 42(12):e102–e107 PubMedCrossRef Duval X, Alla F, Hoen B, Danielou F, Larrieu S, Delahaye F et al (2006) Estimated risk of endocarditis in adults with predisposing cardiac conditions undergoing dental procedures with or without antibiotic prophylaxis. Clin Infect Dis 42(12):e102–e107 PubMedCrossRef
12.
Zurück zum Zitat Poorzand H, Hamidi F, Sheybani F, Ghaderi F, Fazlinezhad A, Alimi H et al (2022) Infective endocarditis: clinical characteristics and Echocardiographic findings. Front Cardiovasc Med 9:789624 PubMedPubMedCentralCrossRef Poorzand H, Hamidi F, Sheybani F, Ghaderi F, Fazlinezhad A, Alimi H et al (2022) Infective endocarditis: clinical characteristics and Echocardiographic findings. Front Cardiovasc Med 9:789624 PubMedPubMedCentralCrossRef
14.
Zurück zum Zitat Kunkel M (2022) Endokarditisprophylaxe: Entwicklungen und aktuelle Empfehlungen. zm (10). ISBN: 978–3–86867–552–8 Kunkel M (2022) Endokarditisprophylaxe: Entwicklungen und aktuelle Empfehlungen. zm (10). ISBN: 978–3–86867–552–8
15.
Zurück zum Zitat Baumgartner H, De Backer J, Babu-Narayan SV, Budts W, Chessa M, Diller GP et al (2021) 2020 ESC Guidelines for the management of adult congenital heart disease. Eur Heart J 42(6):563–645 PubMedCrossRef Baumgartner H, De Backer J, Babu-Narayan SV, Budts W, Chessa M, Diller GP et al (2021) 2020 ESC Guidelines for the management of adult congenital heart disease. Eur Heart J 42(6):563–645 PubMedCrossRef
16.
Zurück zum Zitat Diller GP, Gatzoulis MA (2007) Pulmonary vascular disease in adults with congenital heart disease. Circulation 115(8):1039–1050 PubMedCrossRef Diller GP, Gatzoulis MA (2007) Pulmonary vascular disease in adults with congenital heart disease. Circulation 115(8):1039–1050 PubMedCrossRef
17.
Zurück zum Zitat Duffels MG, Engelfriet PM, Berger RM, van Loon RL, Hoendermis E, Vriend JW et al (2007) Pulmonary arterial hypertension in congenital heart disease: an epidemiologic perspective from a Dutch registry. Int J Cardiol 120(2):198–204 PubMedCrossRef Duffels MG, Engelfriet PM, Berger RM, van Loon RL, Hoendermis E, Vriend JW et al (2007) Pulmonary arterial hypertension in congenital heart disease: an epidemiologic perspective from a Dutch registry. Int J Cardiol 120(2):198–204 PubMedCrossRef
18.
Zurück zum Zitat Lammers AE, Bauer LJ, Diller GP, Helm PC, Abdul-Khaliq H, Bauer UMM et al (2020) Pulmonary hypertension after shunt closure in patients with simple congenital heart defects. Int J Cardiol 308:28–32 PubMedCrossRef Lammers AE, Bauer LJ, Diller GP, Helm PC, Abdul-Khaliq H, Bauer UMM et al (2020) Pulmonary hypertension after shunt closure in patients with simple congenital heart defects. Int J Cardiol 308:28–32 PubMedCrossRef
19.
Zurück zum Zitat van Riel AC, Schuuring MJ, van Hessen ID, Zwinderman AH, Cozijnsen L, Reichert CL et al (2014) Contemporary prevalence of pulmonary arterial hypertension in adult congenital heart disease following the updated clinical classification. Int J Cardiol 174(2):299–305 PubMedCrossRef van Riel AC, Schuuring MJ, van Hessen ID, Zwinderman AH, Cozijnsen L, Reichert CL et al (2014) Contemporary prevalence of pulmonary arterial hypertension in adult congenital heart disease following the updated clinical classification. Int J Cardiol 174(2):299–305 PubMedCrossRef
20.
Zurück zum Zitat Zimmermann R, Schranz D, Ewert P, Kaemmerer H (2013) Pulmonary arterial hypertension in congenital heart defects with shunt: a heterogeneous and complex constellation. Dtsch Med Wochenschr 138(23):1244–1246 PubMed Zimmermann R, Schranz D, Ewert P, Kaemmerer H (2013) Pulmonary arterial hypertension in congenital heart defects with shunt: a heterogeneous and complex constellation. Dtsch Med Wochenschr 138(23):1244–1246 PubMed
21.
Zurück zum Zitat Manes A, Palazzini M, Leci E, Bacchi Reggiani ML, Branzi A, Galie N (2014) Current era survival of patients with pulmonary arterial hypertension associated with congenital heart disease: a comparison between clinical subgroups. Eur Heart J 35(11):716–724 PubMedCrossRef Manes A, Palazzini M, Leci E, Bacchi Reggiani ML, Branzi A, Galie N (2014) Current era survival of patients with pulmonary arterial hypertension associated with congenital heart disease: a comparison between clinical subgroups. Eur Heart J 35(11):716–724 PubMedCrossRef
23.
Zurück zum Zitat Kaemmerer H, Apitz C, Brockmeier K, Eicken A, Gorenflo M, Hager A et al (2018) Pulmonary hypertension in adults with congenital heart disease: Updated recommendations from the Cologne Consensus Conference 2018. Int J Cardiol 272:79–88 CrossRef Kaemmerer H, Apitz C, Brockmeier K, Eicken A, Gorenflo M, Hager A et al (2018) Pulmonary hypertension in adults with congenital heart disease: Updated recommendations from the Cologne Consensus Conference 2018. Int J Cardiol 272:79–88 CrossRef
24.
Zurück zum Zitat Babu-Narayan SV, Giannakoulas G, Valente AM, Li W, Gatzoulis MA (2016) Imaging of congenital heart disease in adults. Eur Heart J 37(15):1182–1195 PubMedCrossRef Babu-Narayan SV, Giannakoulas G, Valente AM, Li W, Gatzoulis MA (2016) Imaging of congenital heart disease in adults. Eur Heart J 37(15):1182–1195 PubMedCrossRef
25.
Zurück zum Zitat D’Alto M, Dimopoulos K, Budts W, Diller GP, Di Salvo G, Dellegrottaglie S et al (2016) Multimodality imaging in congenital heart disease-related pulmonary arterial hypertension. Heart 102(12):910–918 PubMedCrossRef D’Alto M, Dimopoulos K, Budts W, Diller GP, Di Salvo G, Dellegrottaglie S et al (2016) Multimodality imaging in congenital heart disease-related pulmonary arterial hypertension. Heart 102(12):910–918 PubMedCrossRef
26.
Zurück zum Zitat Galie N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A et al (2016) 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Heart J 37(1):67–119 PubMedCrossRef Galie N, Humbert M, Vachiery JL, Gibbs S, Lang I, Torbicki A et al (2016) 2015 ESC/ERS Guidelines for the diagnosis and treatment of pulmonary hypertension: The Joint Task Force for the Diagnosis and Treatment of Pulmonary Hypertension of the European Society of Cardiology (ESC) and the European Respiratory Society (ERS): Endorsed by: Association for European Paediatric and Congenital Cardiology (AEPC), International Society for Heart and Lung Transplantation (ISHLT). Eur Heart J 37(1):67–119 PubMedCrossRef
27.
Zurück zum Zitat Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L et al (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American society of echocardiography and the European association of cardiovascular imaging. Eur Heart J Cardiovasc Imaging 16(3):233–270 PubMedCrossRef Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L et al (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American society of echocardiography and the European association of cardiovascular imaging. Eur Heart J Cardiovasc Imaging 16(3):233–270 PubMedCrossRef
28.
Zurück zum Zitat Zamorano JL, Bax J, Knuuti J, Badano L, Lancellotti P (2015) The ESC textbook of cardiovascular imaging. Oxford University Press CrossRef Zamorano JL, Bax J, Knuuti J, Badano L, Lancellotti P (2015) The ESC textbook of cardiovascular imaging. Oxford University Press CrossRef
29.
Zurück zum Zitat Bedard E, Dimopoulos K, Gatzoulis MA (2009) Has there been any progress made on pregnancy outcomes among women with pulmonary arterial hypertension? Eur Heart J 30(3):256–265 PubMedCrossRef Bedard E, Dimopoulos K, Gatzoulis MA (2009) Has there been any progress made on pregnancy outcomes among women with pulmonary arterial hypertension? Eur Heart J 30(3):256–265 PubMedCrossRef
30.
Zurück zum Zitat Galie N, Beghetti M, Gatzoulis MA, Granton J, Berger RM, Lauer A et al (2006) Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation 114(1):48–54 PubMedCrossRef Galie N, Beghetti M, Gatzoulis MA, Granton J, Berger RM, Lauer A et al (2006) Bosentan therapy in patients with Eisenmenger syndrome: a multicenter, double-blind, randomized, placebo-controlled study. Circulation 114(1):48–54 PubMedCrossRef
31.
Zurück zum Zitat D’Alto M, Romeo E, Argiento P, Sarubbi B, Santoro G, Grimaldi N et al (2012) Bosentan-sildenafil association in patients with congenital heart disease-related pulmonary arterial hypertension and Eisenmenger physiology. Int J Cardiol 155(3):378–382 PubMedCrossRef D’Alto M, Romeo E, Argiento P, Sarubbi B, Santoro G, Grimaldi N et al (2012) Bosentan-sildenafil association in patients with congenital heart disease-related pulmonary arterial hypertension and Eisenmenger physiology. Int J Cardiol 155(3):378–382 PubMedCrossRef
32.
Zurück zum Zitat Iversen K, Jensen AS, Jensen TV, Vejlstrup NG, Sondergaard L (2010) Combination therapy with bosentan and sildenafil in Eisenmenger syndrome: a randomized, placebo-controlled, double-blinded trial. Eur Heart J 31(9):1124–1131 PubMedCrossRef Iversen K, Jensen AS, Jensen TV, Vejlstrup NG, Sondergaard L (2010) Combination therapy with bosentan and sildenafil in Eisenmenger syndrome: a randomized, placebo-controlled, double-blinded trial. Eur Heart J 31(9):1124–1131 PubMedCrossRef
33.
Zurück zum Zitat Cha KS, Cho KI, Seo JS, Choi JH, Park YH, Yang DH et al (2013) Effects of inhaled iloprost on exercise capacity, quality of life, and cardiac function in patients with pulmonary arterial hypertension secondary to congenital heart disease (the Eisenmenger syndrome) (from the EIGER Study). Am J Cardiol 112(11):1834–1839 PubMedCrossRef Cha KS, Cho KI, Seo JS, Choi JH, Park YH, Yang DH et al (2013) Effects of inhaled iloprost on exercise capacity, quality of life, and cardiac function in patients with pulmonary arterial hypertension secondary to congenital heart disease (the Eisenmenger syndrome) (from the EIGER Study). Am J Cardiol 112(11):1834–1839 PubMedCrossRef
34.
Zurück zum Zitat van Riel AC, Blok IM, Zwinderman AH, Wajon EM, Sadee AS, Bakker-de Boo M et al (2015) Lifetime risk of pulmonary hypertension for all patients after shunt closure. J Am Coll Cardiol 66(9):1084–1086 PubMedCrossRef van Riel AC, Blok IM, Zwinderman AH, Wajon EM, Sadee AS, Bakker-de Boo M et al (2015) Lifetime risk of pulmonary hypertension for all patients after shunt closure. J Am Coll Cardiol 66(9):1084–1086 PubMedCrossRef
35.
Zurück zum Zitat Pulido T, Adzerikho I, Channick RN, Delcroix M, Galie N, Ghofrani HA et al (2013) Macitentan and morbidity and mortality in pulmonary arterial hypertension. N Engl J Med 369(9):809–818 PubMedCrossRef Pulido T, Adzerikho I, Channick RN, Delcroix M, Galie N, Ghofrani HA et al (2013) Macitentan and morbidity and mortality in pulmonary arterial hypertension. N Engl J Med 369(9):809–818 PubMedCrossRef
36.
Zurück zum Zitat Sitbon O, Channick R, Chin KM, Frey A, Gaine S, Galie N et al (2015) Selexipag for the treatment of pulmonary arterial hypertension. N Engl J Med 373(26):2522–2533 PubMedCrossRef Sitbon O, Channick R, Chin KM, Frey A, Gaine S, Galie N et al (2015) Selexipag for the treatment of pulmonary arterial hypertension. N Engl J Med 373(26):2522–2533 PubMedCrossRef
37.
Zurück zum Zitat Kaemmerer AS, Freilinger S, Andonian C, Ewert P, Havasi K, Nagdyman N et al (2021) Provision of medical health care for adults with congenital heart disease associated with aortic involvement. Cardiovasc Diagn Ther 11(2):518–528 PubMedPubMedCentralCrossRef Kaemmerer AS, Freilinger S, Andonian C, Ewert P, Havasi K, Nagdyman N et al (2021) Provision of medical health care for adults with congenital heart disease associated with aortic involvement. Cardiovasc Diagn Ther 11(2):518–528 PubMedPubMedCentralCrossRef
38.
40.
Zurück zum Zitat May Khan A, Kim Y (2014) Aortic dilatation and aortopathies in congenital heart disease. Curr Opin Cardiol 29(1):91–96 PubMedCrossRef May Khan A, Kim Y (2014) Aortic dilatation and aortopathies in congenital heart disease. Curr Opin Cardiol 29(1):91–96 PubMedCrossRef
41.
Zurück zum Zitat Niwa K (2005) Aortic root dilatation in tetralogy of Fallot long-term after repair—histology of the aorta in tetralogy of Fallot: evidence of intrinsic aortopathy. Int J Cardiol 103(2):117–119 PubMedCrossRef Niwa K (2005) Aortic root dilatation in tetralogy of Fallot long-term after repair—histology of the aorta in tetralogy of Fallot: evidence of intrinsic aortopathy. Int J Cardiol 103(2):117–119 PubMedCrossRef
43.
44.
Zurück zum Zitat Niwa K, Perloff JK, Bhuta SM, Laks H, Drinkwater DC, Child JS et al (2001) Structural abnormalities of great arterial walls in congenital heart disease: light and electron microscopic analyses. Circulation 103(3):393–400 PubMedCrossRef Niwa K, Perloff JK, Bhuta SM, Laks H, Drinkwater DC, Child JS et al (2001) Structural abnormalities of great arterial walls in congenital heart disease: light and electron microscopic analyses. Circulation 103(3):393–400 PubMedCrossRef
45.
Zurück zum Zitat von Kodolitsch Y, Rybczynski M, Vogler M, Mir TS, Schüler H, Kutsche K et al (2016) The role of the multidisciplinary health care team in the management of patients with Marfan syndrome. J Multidiscip Healthc 9:587 CrossRef von Kodolitsch Y, Rybczynski M, Vogler M, Mir TS, Schüler H, Kutsche K et al (2016) The role of the multidisciplinary health care team in the management of patients with Marfan syndrome. J Multidiscip Healthc 9:587 CrossRef
46.
Zurück zum Zitat Neidenbach R, Niwa K, Oto O, Oechslin E, Aboulhosn J, Celermajer D et al (2018) Improving medical care and prevention in adults with congenital heart disease—Reflections on a global problem—part II: infective endocarditis, pulmonary hypertension, pulmonary arterial hypertension and aortopathy. Cardiovasc Diagn Ther 8(6):716–724 PubMedPubMedCentralCrossRef Neidenbach R, Niwa K, Oto O, Oechslin E, Aboulhosn J, Celermajer D et al (2018) Improving medical care and prevention in adults with congenital heart disease—Reflections on a global problem—part II: infective endocarditis, pulmonary hypertension, pulmonary arterial hypertension and aortopathy. Cardiovasc Diagn Ther 8(6):716–724 PubMedPubMedCentralCrossRef
47.
Zurück zum Zitat Zanjani KS, Niwa K (2013) Aortic dilatation and aortopathy in congenital heart diseases. J Cardiol 61(1):16–21 PubMedCrossRef Zanjani KS, Niwa K (2013) Aortic dilatation and aortopathy in congenital heart diseases. J Cardiol 61(1):16–21 PubMedCrossRef
48.
Zurück zum Zitat Niwa K (2013) Aortopathy in congenital heart disease in adults: Aortic dilatation with decreased aortic elasticity that impacts negatively on left ventricular function. Korean Circ J 43(4):215–220 PubMedPubMedCentralCrossRef Niwa K (2013) Aortopathy in congenital heart disease in adults: Aortic dilatation with decreased aortic elasticity that impacts negatively on left ventricular function. Korean Circ J 43(4):215–220 PubMedPubMedCentralCrossRef
49.
Zurück zum Zitat Senzaki H, Iwamoto Y, Ishido H, Matsunaga T, Taketazu M, Kobayashi T et al (2008) Arterial haemodynamics in patients after repair of tetralogy of Fallot: influence on left ventricular after load and aortic dilatation. Heart 94(1):70–74 PubMedCrossRef Senzaki H, Iwamoto Y, Ishido H, Matsunaga T, Taketazu M, Kobayashi T et al (2008) Arterial haemodynamics in patients after repair of tetralogy of Fallot: influence on left ventricular after load and aortic dilatation. Heart 94(1):70–74 PubMedCrossRef
50.
Zurück zum Zitat Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H et al (2014) 2014 ESC guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The task force for the diagnosis and treatment of aortic diseases of the European society of cardiology (ESC). Eur Heart J 35(41):2873–2926 PubMedCrossRef Erbel R, Aboyans V, Boileau C, Bossone E, Bartolomeo RD, Eggebrecht H et al (2014) 2014 ESC guidelines on the diagnosis and treatment of aortic diseases: document covering acute and chronic aortic diseases of the thoracic and abdominal aorta of the adult. The task force for the diagnosis and treatment of aortic diseases of the European society of cardiology (ESC). Eur Heart J 35(41):2873–2926 PubMedCrossRef
51.
Zurück zum Zitat Di Salvo G, Miller O, Narayan BS, Li W, Budts W, Valsangiacomo Buechel ER et al (2018) Imaging the adult with congenital heart disease: a multimodality imaging approach—Position paper from the EACVI. Eur Heart J Cardiovasc Imaging 19(10):1077–1098 PubMedCrossRef Di Salvo G, Miller O, Narayan BS, Li W, Budts W, Valsangiacomo Buechel ER et al (2018) Imaging the adult with congenital heart disease: a multimodality imaging approach—Position paper from the EACVI. Eur Heart J Cardiovasc Imaging 19(10):1077–1098 PubMedCrossRef
52.
Zurück zum Zitat Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L et al (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 28(1):1–39.e14 PubMedCrossRef Lang RM, Badano LP, Mor-Avi V, Afilalo J, Armstrong A, Ernande L et al (2015) Recommendations for cardiac chamber quantification by echocardiography in adults: an update from the American Society of Echocardiography and the European Association of Cardiovascular Imaging. J Am Soc Echocardiogr 28(1):1–39.e14 PubMedCrossRef
53.
Zurück zum Zitat von Kodolitsch Y, Kutsche K (2017) Genetic diagnostics of inherited aortic diseases: Medical strategy analysis. Herz 42(5):459–467 CrossRef von Kodolitsch Y, Kutsche K (2017) Genetic diagnostics of inherited aortic diseases: Medical strategy analysis. Herz 42(5):459–467 CrossRef
54.
Zurück zum Zitat Loeys BL, Dietz HC, Braverman AC, Callewaert BL, De Backer J, Devereux RB et al (2010) The revised Ghent nosology for the Marfan syndrome. J Med Genet 47(7):476–485 PubMedCrossRef Loeys BL, Dietz HC, Braverman AC, Callewaert BL, De Backer J, Devereux RB et al (2010) The revised Ghent nosology for the Marfan syndrome. J Med Genet 47(7):476–485 PubMedCrossRef
55.
Zurück zum Zitat Huntgeburth M, Neidenbach RC, von Kodolitsch Y, Kaemmerer H (2018) Genetisch bedingte Aortenerkrankungen – Empfehlungen für Kardiologen in Praxis und Klinik—Genetic Aortic Syndromes—Recommendations for Cardiologists in Practice and Clinic. Aktuel Kardiol 7(03):220–230 CrossRef Huntgeburth M, Neidenbach RC, von Kodolitsch Y, Kaemmerer H (2018) Genetisch bedingte Aortenerkrankungen – Empfehlungen für Kardiologen in Praxis und Klinik—Genetic Aortic Syndromes—Recommendations for Cardiologists in Practice and Clinic. Aktuel Kardiol 7(03):220–230 CrossRef
56.
Zurück zum Zitat Beckmann A, Meyer R, Lewandowski J, Markewitz A, Blaßfeld D, Böning A (2022) German heart surgery report 2021: the annual updated registry of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 70(5):362–376 PubMedCrossRef Beckmann A, Meyer R, Lewandowski J, Markewitz A, Blaßfeld D, Böning A (2022) German heart surgery report 2021: the annual updated registry of the German Society for Thoracic and Cardiovascular Surgery. Thorac Cardiovasc Surg 70(5):362–376 PubMedCrossRef
57.
Zurück zum Zitat Vouhé PR (2011) Adult congenital surgery: current management. Semin Thorac Cardiovasc Surg 23(3):209–215 PubMedCrossRef Vouhé PR (2011) Adult congenital surgery: current management. Semin Thorac Cardiovasc Surg 23(3):209–215 PubMedCrossRef
58.
Zurück zum Zitat Klcovansky J, Søndergaard L, Helvind M, Andersen H (2008) Cardiac surgery in grown-up congenital heart patients. Will the surgical workload increase? Interact CardioVasc Thorac Surg 7(1):84–89 PubMedCrossRef Klcovansky J, Søndergaard L, Helvind M, Andersen H (2008) Cardiac surgery in grown-up congenital heart patients. Will the surgical workload increase? Interact CardioVasc Thorac Surg 7(1):84–89 PubMedCrossRef
59.
Zurück zum Zitat Berdat PA, Immer F, Pfammatter JP, Carrel T (2004) Reoperations in adults with congenital heart disease: analysis of early outcome. Int J Cardiol 93(2–3):239–245 PubMedCrossRef Berdat PA, Immer F, Pfammatter JP, Carrel T (2004) Reoperations in adults with congenital heart disease: analysis of early outcome. Int J Cardiol 93(2–3):239–245 PubMedCrossRef
60.
Zurück zum Zitat Kindzelski BA, Bakaeen FG, Tong MZ, Roselli EE, Soltesz EG, Johnston DR et al (2022) Modern practice and outcomes of reoperative cardiac surgery. J Thorac Cardiovasc Surg 164(6):1755–1766.e16 PubMedCrossRef Kindzelski BA, Bakaeen FG, Tong MZ, Roselli EE, Soltesz EG, Johnston DR et al (2022) Modern practice and outcomes of reoperative cardiac surgery. J Thorac Cardiovasc Surg 164(6):1755–1766.e16 PubMedCrossRef
61.
Zurück zum Zitat Lemmer J, Heise G, Rentzsch A, Boettler P, Kuehne T, Dubowy KO et al (2011) Right ventricular function in grown-up patients after correction of congenital right heart disease. Clin Res Cardiol 100(4):289–296 PubMedCrossRef Lemmer J, Heise G, Rentzsch A, Boettler P, Kuehne T, Dubowy KO et al (2011) Right ventricular function in grown-up patients after correction of congenital right heart disease. Clin Res Cardiol 100(4):289–296 PubMedCrossRef
62.
Zurück zum Zitat Mauriat P, Bojan M, Soulie S, Foulgoc H, Tafer N, Ouattara A (2020) Impact of the perioperative inotropic support in grown-up congenital heart patients undergoing cardiac surgery: a propensity score adjusted analysis. Ann Intensive Care 10(1):91 PubMedPubMedCentralCrossRef Mauriat P, Bojan M, Soulie S, Foulgoc H, Tafer N, Ouattara A (2020) Impact of the perioperative inotropic support in grown-up congenital heart patients undergoing cardiac surgery: a propensity score adjusted analysis. Ann Intensive Care 10(1):91 PubMedPubMedCentralCrossRef
63.
Zurück zum Zitat Hosseinpour AR, Cullen S, Tsang VT (2006) Transplantation for adults with congenital heart disease. Eur J Cardiothorac Surg 30(3):508–514 PubMedCrossRef Hosseinpour AR, Cullen S, Tsang VT (2006) Transplantation for adults with congenital heart disease. Eur J Cardiothorac Surg 30(3):508–514 PubMedCrossRef
64.
Zurück zum Zitat Haapanen H, Tsang V, Kempny A, Neijenhuis R, Kennedy F, Cullen S et al (2020) Grown-up congenital heart surgery in 1093 consecutive cases: a “hidden” burden of early outcome. Ann Thorac Surg 110(5):1667–1676 PubMedCrossRef Haapanen H, Tsang V, Kempny A, Neijenhuis R, Kennedy F, Cullen S et al (2020) Grown-up congenital heart surgery in 1093 consecutive cases: a “hidden” burden of early outcome. Ann Thorac Surg 110(5):1667–1676 PubMedCrossRef
65.
Zurück zum Zitat van Rijen EH, Utens EM, Roos-Hesselink JW, Meijboom FJ, van Domburg RT, Roelandt JR et al (2004) Medical predictors for psychopathology in adults with operated congenital heart disease. Eur Heart J 25(18):1605–1613 PubMedCrossRef van Rijen EH, Utens EM, Roos-Hesselink JW, Meijboom FJ, van Domburg RT, Roelandt JR et al (2004) Medical predictors for psychopathology in adults with operated congenital heart disease. Eur Heart J 25(18):1605–1613 PubMedCrossRef
66.
Zurück zum Zitat Albus C, Waller C, Fritzsche K, Gunold H, Haass M, Hamann B et al (2018) Bedeutung von psychosozialen Faktoren in der Kardiologie – Update 2018. Kardiologe 12(5):312–331 CrossRef Albus C, Waller C, Fritzsche K, Gunold H, Haass M, Hamann B et al (2018) Bedeutung von psychosozialen Faktoren in der Kardiologie – Update 2018. Kardiologe 12(5):312–331 CrossRef
67.
Zurück zum Zitat Nagdyman N, Huntgeburth M, Hager A, Neidenbach R, Ewert P, Kaemmerer H (2016) Belastungen bei Erwachsenen mit angeborenen Herzfehlern (EMAH): Sport, Beruf, Familienplanung und Schwangerschaft. Herzmedizin 16(26) Nagdyman N, Huntgeburth M, Hager A, Neidenbach R, Ewert P, Kaemmerer H (2016) Belastungen bei Erwachsenen mit angeborenen Herzfehlern (EMAH): Sport, Beruf, Familienplanung und Schwangerschaft. Herzmedizin 16(26)
68.
Zurück zum Zitat Kaemmerer H, Freilinger S, Neidenbach R, Achenbach S, Andonian C, Ewert P et al (2022) Versorgung von Erwachsenen mit angeborenen Herzfehlern in Deutschland – tragende Rolle von Internisten und Hausärzten. Internist 63(1):95–102 PubMedCrossRef Kaemmerer H, Freilinger S, Neidenbach R, Achenbach S, Andonian C, Ewert P et al (2022) Versorgung von Erwachsenen mit angeborenen Herzfehlern in Deutschland – tragende Rolle von Internisten und Hausärzten. Internist 63(1):95–102 PubMedCrossRef
69.
Zurück zum Zitat Fteropoulli T, Stygall J, Cullen S, Deanfield J, Newman SP (2013) Quality of life of adult congenital heart disease patients: a systematic review of the literature. Cardiol Young 23(4):473–485 PubMedCrossRef Fteropoulli T, Stygall J, Cullen S, Deanfield J, Newman SP (2013) Quality of life of adult congenital heart disease patients: a systematic review of the literature. Cardiol Young 23(4):473–485 PubMedCrossRef
70.
Zurück zum Zitat Marino BS, Lipkin PH, Newburger JW, Peacock G, Gerdes M, Gaynor JW et al (2012) Neurodevelopmental outcomes in children with congenital heart disease: evaluation and management: a scientific statement from the American Heart Association. Circulation 126(9):1143–1172 PubMedCrossRef Marino BS, Lipkin PH, Newburger JW, Peacock G, Gerdes M, Gaynor JW et al (2012) Neurodevelopmental outcomes in children with congenital heart disease: evaluation and management: a scientific statement from the American Heart Association. Circulation 126(9):1143–1172 PubMedCrossRef
71.
Zurück zum Zitat Neidenbach RC, Lummert E, Vigl M, Zachoval R, Fischereder M, Engelhardt A et al (2018) Non-cardiac comorbidities in adults with inherited and congenital heart disease: report from a single center experience of more than 800 consecutive patients. Cardiovasc Diagn Ther 8(4):423–431 PubMedPubMedCentralCrossRef Neidenbach RC, Lummert E, Vigl M, Zachoval R, Fischereder M, Engelhardt A et al (2018) Non-cardiac comorbidities in adults with inherited and congenital heart disease: report from a single center experience of more than 800 consecutive patients. Cardiovasc Diagn Ther 8(4):423–431 PubMedPubMedCentralCrossRef
72.
Zurück zum Zitat Sliwa K, van der Meer P, Petrie MC, Frogoudaki A, Johnson MR, Hilfiker-Kleiner D et al (2021) Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. Eur J Heart Fail 23(4):527–540 PubMedCrossRef Sliwa K, van der Meer P, Petrie MC, Frogoudaki A, Johnson MR, Hilfiker-Kleiner D et al (2021) Risk stratification and management of women with cardiomyopathy/heart failure planning pregnancy or presenting during/after pregnancy: a position statement from the Heart Failure Association of the European Society of Cardiology Study Group on Peripartum Cardiomyopathy. Eur J Heart Fail 23(4):527–540 PubMedCrossRef
73.
Zurück zum Zitat Deng LX, Khan AM, Drajpuch D, Fuller S, Ludmir J, Mascio CE et al (2016) Prevalence and correlates of post-traumatic stress disorder in adults with congenital heart disease. Am J Cardiol 117(5):853–857 PubMedCrossRef Deng LX, Khan AM, Drajpuch D, Fuller S, Ludmir J, Mascio CE et al (2016) Prevalence and correlates of post-traumatic stress disorder in adults with congenital heart disease. Am J Cardiol 117(5):853–857 PubMedCrossRef
74.
Zurück zum Zitat Jackson JL, Leslie CE, Hondorp SN (2018) Depressive and anxiety symptoms in adult congenital heart disease: Prevalence, health impact and treatment. Prog Cardiovasc Dis 61(3–4):294–299 PubMedCrossRef Jackson JL, Leslie CE, Hondorp SN (2018) Depressive and anxiety symptoms in adult congenital heart disease: Prevalence, health impact and treatment. Prog Cardiovasc Dis 61(3–4):294–299 PubMedCrossRef
75.
Zurück zum Zitat Kovacs AH, Utens EM (2015) More than Just the heart: transition and psychosocial issues in adult congenital heart disease. Cardiol Clin 33(4):625–634 PubMedCrossRef Kovacs AH, Utens EM (2015) More than Just the heart: transition and psychosocial issues in adult congenital heart disease. Cardiol Clin 33(4):625–634 PubMedCrossRef
76.
Zurück zum Zitat Kronwitter A, Mebus S, Neidenbach R, Tutarel O, Ewert P, Kaemmerer H et al (2019) Psychosocial situation in adults with congenital heart defects today and 20 years ago: Any changes? Int J Cardiol 275:70–76 PubMedCrossRef Kronwitter A, Mebus S, Neidenbach R, Tutarel O, Ewert P, Kaemmerer H et al (2019) Psychosocial situation in adults with congenital heart defects today and 20 years ago: Any changes? Int J Cardiol 275:70–76 PubMedCrossRef
77.
Zurück zum Zitat Moons P, Bratt EL, De Backer J, Goossens E, Hornung T, Tutarel O et al (2021) Transition to adulthood and transfer to adult care of adolescents with congenital heart disease: a global consensus statement of the ESC Association of Cardiovascular Nursing and Allied Professions (ACNAP), the ESC Working Group on Adult Congenital Heart Disease (WG ACHD), the Association for European Paediatric and Congenital Cardiology (AEPC), the Pan-African Society of Cardiology (PASCAR), the Asia-Pacific Pediatric Cardiac Society (APPCS), the Inter-American Society of Cardiology (IASC), the Cardiac Society of Australia and New Zealand (CSANZ), the International Society for Adult Congenital Heart Disease (ISACHD), the World Heart Federation (WHF), the European Congenital Heart Disease Organisation (ECHDO), and the Global Alliance for Rheumatic and Congenital Hearts (Global ARCH). Eur Heart J 42(41):4213–4223 PubMedPubMedCentralCrossRef Moons P, Bratt EL, De Backer J, Goossens E, Hornung T, Tutarel O et al (2021) Transition to adulthood and transfer to adult care of adolescents with congenital heart disease: a global consensus statement of the ESC Association of Cardiovascular Nursing and Allied Professions (ACNAP), the ESC Working Group on Adult Congenital Heart Disease (WG ACHD), the Association for European Paediatric and Congenital Cardiology (AEPC), the Pan-African Society of Cardiology (PASCAR), the Asia-Pacific Pediatric Cardiac Society (APPCS), the Inter-American Society of Cardiology (IASC), the Cardiac Society of Australia and New Zealand (CSANZ), the International Society for Adult Congenital Heart Disease (ISACHD), the World Heart Federation (WHF), the European Congenital Heart Disease Organisation (ECHDO), and the Global Alliance for Rheumatic and Congenital Hearts (Global ARCH). Eur Heart J 42(41):4213–4223 PubMedPubMedCentralCrossRef
78.
Zurück zum Zitat Kaemmerer H, Breithardt G (2006) Recommendations for the quality improvement of interdisciplinary care of adults with congenital heart anomalies. Clin Res Cardiol 95(Suppl 4):76–84 PubMedCrossRef Kaemmerer H, Breithardt G (2006) Recommendations for the quality improvement of interdisciplinary care of adults with congenital heart anomalies. Clin Res Cardiol 95(Suppl 4):76–84 PubMedCrossRef
79.
Zurück zum Zitat Kaemmerer H, Bauer U, de Haan F, Flesch J, Gohlke-Bärwolf C, Hagl S et al (2011) Recommendations for improving the quality of the interdisciplinary medical care of grown-ups with congenital heart disease (GUCH). Int J Cardiol 150(1):59–64 PubMedCrossRef Kaemmerer H, Bauer U, de Haan F, Flesch J, Gohlke-Bärwolf C, Hagl S et al (2011) Recommendations for improving the quality of the interdisciplinary medical care of grown-ups with congenital heart disease (GUCH). Int J Cardiol 150(1):59–64 PubMedCrossRef
80.
Zurück zum Zitat Westhoff-Bleck M, Briest J, Fraccarollo D, Hilfiker-Kleiner D, Winter L, Maske U et al (2016) Mental disorders in adults with congenital heart disease: Unmet needs and impact on quality of life. J Affect Disord 204:180–186 PubMedCrossRef Westhoff-Bleck M, Briest J, Fraccarollo D, Hilfiker-Kleiner D, Winter L, Maske U et al (2016) Mental disorders in adults with congenital heart disease: Unmet needs and impact on quality of life. J Affect Disord 204:180–186 PubMedCrossRef
81.
Zurück zum Zitat Andonian C, Beckmann J, Ewert P, Freilinger S, Kaemmerer H, Oberhoffer-Fritz R et al (2020) Assessment of the psychological situation in adults with congenital heart disease. J Clin Med 9(3):779 PubMedPubMedCentralCrossRef Andonian C, Beckmann J, Ewert P, Freilinger S, Kaemmerer H, Oberhoffer-Fritz R et al (2020) Assessment of the psychological situation in adults with congenital heart disease. J Clin Med 9(3):779 PubMedPubMedCentralCrossRef
82.
Zurück zum Zitat Diller GP, Körten MA, Bauer UM, Miera O, Tutarel O, Kaemmerer H et al (2016) Current therapy and outcome of Eisenmenger syndrome: data of the German National Register for congenital heart defects. Eur Heart J 37(18):1449–1455 PubMedPubMedCentralCrossRef Diller GP, Körten MA, Bauer UM, Miera O, Tutarel O, Kaemmerer H et al (2016) Current therapy and outcome of Eisenmenger syndrome: data of the German National Register for congenital heart defects. Eur Heart J 37(18):1449–1455 PubMedPubMedCentralCrossRef
84.
Zurück zum Zitat Kaemmerer H, Hess J (2009) Congenital heart disease. Transition from adolescence to adulthood. Internist (Berl) 50(10):1221–1227 PubMedCrossRef Kaemmerer H, Hess J (2009) Congenital heart disease. Transition from adolescence to adulthood. Internist (Berl) 50(10):1221–1227 PubMedCrossRef
85.
Zurück zum Zitat Kaemmerer H, Andonian C, Ewert P, Freilinger S, Nagdyman N, Neidenbach R et al (2021) Transition – Nachsorge für Erwachsene mit angeborenen Herzfehlern. Dtsch Med Wochenschr 146(18):1192–1199 PubMedCrossRef Kaemmerer H, Andonian C, Ewert P, Freilinger S, Nagdyman N, Neidenbach R et al (2021) Transition – Nachsorge für Erwachsene mit angeborenen Herzfehlern. Dtsch Med Wochenschr 146(18):1192–1199 PubMedCrossRef
86.
Zurück zum Zitat Baumgartner H, De Backer J (2020) The ESC clinical practice guidelines for the management of adult congenital heart disease 2020. Eur Heart J 41(43):4153–4154 PubMedCrossRef Baumgartner H, De Backer J (2020) The ESC clinical practice guidelines for the management of adult congenital heart disease 2020. Eur Heart J 41(43):4153–4154 PubMedCrossRef
87.
Zurück zum Zitat Diller GP, Arvanitaki A, Opotowsky AR, Jenkins K, Moons P, Kempny A et al (2021) Lifespan perspective on congenital heart disease research. J Am Coll Cardiol 77(17):2219–2235 PubMedCrossRef Diller GP, Arvanitaki A, Opotowsky AR, Jenkins K, Moons P, Kempny A et al (2021) Lifespan perspective on congenital heart disease research. J Am Coll Cardiol 77(17):2219–2235 PubMedCrossRef
88.
Zurück zum Zitat Diller GP, Orwat S, Lammers AE, Radke RM, De-Torres-Alba F, Schmidt R et al (2021) Lack of specialist care is associated with increased morbidity and mortality in adult congenital heart disease: a population-based study. Eur Heart J 42(41):4241–4248 PubMedCrossRef Diller GP, Orwat S, Lammers AE, Radke RM, De-Torres-Alba F, Schmidt R et al (2021) Lack of specialist care is associated with increased morbidity and mortality in adult congenital heart disease: a population-based study. Eur Heart J 42(41):4241–4248 PubMedCrossRef
Metadaten
Titel
„Erwachsene mit angeborenen Herzfehlern“: Aktuelle Herausforderung in der medizinischen Versorgung Teil II: Infektiöse Endokarditis, pulmonale Hypertonie, Aortopathien, herzchirurgische Aspekte, Psychokardiologie, ungelöste Probleme und Zukunftsaspekte
Positionspapier der Deutschen Gesellschaft für Kardiologie
verfasst von
Prof. Dr. Dr. Harald Kaemmerer
Stephan Baldus
Helmut Baumgartner
Felix Berger
Fokko de Haan
Stefan Frantz
Dirk Loßnitzer
Anselm Uebing
Corinna Lebherz
Michael Weyand
Gerhard Paul Diller
Publikationsdatum
06.07.2023
Verlag
Springer Medizin
Erschienen in
Die Kardiologie / Ausgabe 5/2023
Print ISSN: 2731-7129
Elektronische ISSN: 2731-7137
DOI
https://doi.org/10.1007/s12181-023-00617-0

Weitere Artikel der Ausgabe 5/2023

Die Kardiologie 5/2023 Zur Ausgabe

Update Innere Medizin

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.