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Erschienen in:

20.07.2023 | Original Article

Pulmonary Tuberculosis in Severely Malnourished Children Admitted to Nutrition Rehabilitation Centers: A Multicenter Study

verfasst von: Manjula Singh, Bhavna Dhingra, Bipra Bishnu, Dhruvendra Pandey, Praveen K. Anand, Sarika Gupta, Vidyanand Ravi Das, Nitin Dhochak, S. K. Kabra, NRC Group

Erschienen in: Indian Journal of Pediatrics | Ausgabe 8/2024

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Abstract

Objectives

To identify prevalence of pulmonary tuberculosis (TB) in severely malnourished children admitted to nutritional rehabilitation centers.

Methods

A multicenter cross-sectional study involving 41 nutrition rehabilitation centres (NRCs) across India was carried out to document prevalence of pulmonary tuberculosis in acute severe malnourished children admitted in NRCs. After training of the NRC staff to follow algorithm provided by national tuberculosis elimination program, children admitted to NRCs were screened for pulmonary tuberculosis.

Results

A total of 4356 children were enrolled across all the sites. Gastric aspirate for Cartridge based nucleic acid amplification test (CBNAAT), tuberculin skin test (TST) and X-ray film of chest were done in more than 99% of enrolled subjects. A total of 189 children (4.3%) had pulmonary tuberculosis. Eighty-seven (1.99%) were microbiologically confirmed by positive CBNAAT. On multivariate analysis, only significant association was with history of contact with TB patient in family.

Conclusions

The present results suggest that a significant proportion (>4%) of children admitted in NRCs suffer from pulmonary tuberculosis. It is feasible to improve diagnosis of tuberculosis as a whole and microbiologically confirmed TB.
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Metadaten
Titel
Pulmonary Tuberculosis in Severely Malnourished Children Admitted to Nutrition Rehabilitation Centers: A Multicenter Study
verfasst von
Manjula Singh
Bhavna Dhingra
Bipra Bishnu
Dhruvendra Pandey
Praveen K. Anand
Sarika Gupta
Vidyanand Ravi Das
Nitin Dhochak
S. K. Kabra
NRC Group
Publikationsdatum
20.07.2023
Verlag
Springer India
Erschienen in
Indian Journal of Pediatrics / Ausgabe 8/2024
Print ISSN: 0019-5456
Elektronische ISSN: 0973-7693
DOI
https://doi.org/10.1007/s12098-023-04723-5

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