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Erschienen in: Heart and Vessels 3/2018

03.10.2017 | Original Article

Pulse wave travel distance as a novel marker of ventricular-arterial coupling

verfasst von: Yurie Obata, Pavel Ruzankin, Allan Gottschalk, Daniel Nyhan, Dan E. Berkowitz, Jochen Steppan, Viachaslau Barodka

Erschienen in: Heart and Vessels | Ausgabe 3/2018

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Abstract

Each stroke volume ejected by the heart is distributed along the arterial system as a pressure waveform. How far the front of the pressure waveform travels within the arterial system depends both on the pulse wave velocity (PWV) and the ejection time (ET). We tested the hypothesis that ET and PWV are coupled together, in order to produce a pulse wave travel distance (PWTD = PWV × ET) which would match the distance from the heart to the most distant site in the arterial system. The study was conducted in 11 healthy volunteers. We recorded lead II of the ECG along with pulse plethysmography at ear, finger and toe. The ET at the ear and pulse arrival time to each peripheral site were extracted. We then calculated PWV followed by PWTD for each location. Taken into account the individual subject variability PWTDToe in the supine position was 153 cm (95% CI 146–160 cm). It was not different from arterial pathway distance from the heart to the toe (D Toe 153 cm). The PWTDFinger and PWTDEar were longer than the distance from the heart to the finger and ear irrespective of body position. ETEar and PWVToe appear to be coupled in healthy subjects to produce a PWTD that is roughly equivalent to the arterial pathway distance to the toe. We propose that PWTD should be evaluated further to test its potential as a noninvasive parameter of ventricular-arterial coupling in subjects with cardiovascular diseases.
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Metadaten
Titel
Pulse wave travel distance as a novel marker of ventricular-arterial coupling
verfasst von
Yurie Obata
Pavel Ruzankin
Allan Gottschalk
Daniel Nyhan
Dan E. Berkowitz
Jochen Steppan
Viachaslau Barodka
Publikationsdatum
03.10.2017
Verlag
Springer Japan
Erschienen in
Heart and Vessels / Ausgabe 3/2018
Print ISSN: 0910-8327
Elektronische ISSN: 1615-2573
DOI
https://doi.org/10.1007/s00380-017-1058-4

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