Skip to main content
Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology 6/2009

01.06.2009 | Neuro-ophthalmology

Pupil campimetry in patients with retinitis pigmentosa and functional visual field loss

verfasst von: Karolína Skorkovská, Holger Lüdtke, Helmut Wilhelm, Barbara Wilhelm

Erschienen in: Graefe's Archive for Clinical and Experimental Ophthalmology | Ausgabe 6/2009

Einloggen, um Zugang zu erhalten

Abstract

Background

The aim of our study was to test in a small series of cases if pupil perimetry can prove real concentric visual field loss in retinal degeneration and distinguish from feigned visual field loss.

Methods

By means of infrared-video-pupillography, light responses to perimetric stimuli were recorded. The stimulus pattern consisted of 41 stimuli presented in the central 30° visual field. Stimulus intensity was 140 cd/m2. 5 healthy subjects, 6 patients with retinitis pigmentosa and 2 patients with suspected functional visual field loss were examined.

Results

Pupil perimetry was able to reproduce the visual field in retinitis pigmentosa very well. Normal subjects and patients with suspected feigned visual field loss showed normal pupillomotor fields, different from the findings in retinitis pigmentosa.

Conclusions

This study provides sufficient evidence that pupil campimetry is applicable for differentiating between retinal dystrophy and functional concentric visual field loss. Possible residual light sensitivity of the blind retina due to melanopsin ganglion cells is obviously not sufficient to provide a pupillary light response to perimetric stimuli.
Literatur
1.
Zurück zum Zitat Lucas RJ, Douglas RH, Foster RG (2001) Characterisation of an ocular photopigment capable of driving pupillary constriction in mice. Nat Neurosci 4:621–626 doi:10.1038/88443 PubMedCrossRef Lucas RJ, Douglas RH, Foster RG (2001) Characterisation of an ocular photopigment capable of driving pupillary constriction in mice. Nat Neurosci 4:621–626 doi:10.​1038/​88443 PubMedCrossRef
3.
4.
Zurück zum Zitat Kardon RH, Kirkali PA, Thompson HS (1991) Automated pupil perimetry. Ophthalmology 98:485–496PubMed Kardon RH, Kirkali PA, Thompson HS (1991) Automated pupil perimetry. Ophthalmology 98:485–496PubMed
6.
Zurück zum Zitat Bresky R, Charles S (1969) Pupil motor perimetry. Am J Ophthalmol 68:108–112PubMed Bresky R, Charles S (1969) Pupil motor perimetry. Am J Ophthalmol 68:108–112PubMed
8.
Zurück zum Zitat Moore PA, Kardon RH (1995) Functional visual field loss: comparison of visual and pupil perimetry. Invest Ophthalmol Vis Sci 36(Suppl):S455 Moore PA, Kardon RH (1995) Functional visual field loss: comparison of visual and pupil perimetry. Invest Ophthalmol Vis Sci 36(Suppl):S455
9.
Zurück zum Zitat Yoshitomi T, Matsui T, Mukuno K et al (1996) Objective visual field measurement using pupil perimetry - clinical applications. Invest Ophthalmol Vis Sci 37(Suppl):S160 Yoshitomi T, Matsui T, Mukuno K et al (1996) Objective visual field measurement using pupil perimetry - clinical applications. Invest Ophthalmol Vis Sci 37(Suppl):S160
11.
Zurück zum Zitat Hong S, Narkiewicz J, Kardon RH (2001) Comparison of pupil perimetry and visual perimetry in normal eyes: decibel sensitivity and variability. Invest Ophthalmol Vis Sci 42:957–965PubMed Hong S, Narkiewicz J, Kardon RH (2001) Comparison of pupil perimetry and visual perimetry in normal eyes: decibel sensitivity and variability. Invest Ophthalmol Vis Sci 42:957–965PubMed
14.
Zurück zum Zitat Clarke RJ, Ikeda H (1985) Luminance and darkness detectors in the olivary and posterior pretectal nuclei and their relationship to the pupillary light reflex in the rat. Studies with steady luminance levels. Exp Brain Res 57:224–232 doi:10.1007/BF00236527 Clarke RJ, Ikeda H (1985) Luminance and darkness detectors in the olivary and posterior pretectal nuclei and their relationship to the pupillary light reflex in the rat. Studies with steady luminance levels. Exp Brain Res 57:224–232 doi:10.​1007/​BF00236527
Metadaten
Titel
Pupil campimetry in patients with retinitis pigmentosa and functional visual field loss
verfasst von
Karolína Skorkovská
Holger Lüdtke
Helmut Wilhelm
Barbara Wilhelm
Publikationsdatum
01.06.2009
Verlag
Springer-Verlag
Erschienen in
Graefe's Archive for Clinical and Experimental Ophthalmology / Ausgabe 6/2009
Print ISSN: 0721-832X
Elektronische ISSN: 1435-702X
DOI
https://doi.org/10.1007/s00417-008-1015-0

Weitere Artikel der Ausgabe 6/2009

Graefe's Archive for Clinical and Experimental Ophthalmology 6/2009 Zur Ausgabe

Neu im Fachgebiet Augenheilkunde

Update Augenheilkunde

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert.