The online version of this article (https://doi.org/10.1186/s12885-018-4604-2) contains supplementary material, which is available to authorized users.
Quality of cancer care (QoCC) has become an important item for providers, regulators and purchasers of care worldwide. Aim of this study is to present the results of some evidence-based quality indicators (QI) for prostate cancer (PC) at the population-based level and to compare the outcomes with data available in the literature.
The study included all PC diagnosed on a three years period analysis (01.01.2011–31.12.2013) in the population of Canton Ticino (Southern Switzerland) extracted from the Ticino Cancer Registry database. 13 QI, approved through the validated Delphi methodology, were calculated using the “available case” approach: 2 for diagnosis, 4 for pathology, 6 for treatment and 1 for outcome. The selection of the computed QI was based on the availability of medical documentation. QI are presented as proportion (%) with the corresponding 95% confidence interval.
700 PC were detected during the three-year period 2011–2013: 78.3% of them were diagnosed through a prostatic biopsy and for 72.5% 8 or more biopsy cores were taken. 46.5% of the low risk PC patients underwent active surveillance, while 69.2% of high risk PC underwent a radical treatment (radical prostatectomy, radiotherapy or brachytherapy) and 73.5% of patients with metastatic PC were treated with hormonal therapy. The overall 30-day postoperative mortality was 0.5%.
Results emerging from this study on the QoCC for PC in Canton Ticino are encouraging: the choice of treatment modalities seems to respect the international guidelines and our results are comparable to the scarce number of available international studies. Additional national and international standardisation of the QI and further QI population-based studies are needed in order to get a real picture of the PC diagnostic-therapeutic process progress through the definition of thresholds of minimal standard of care.
Additional file 1: List of QI assessed and selected for prostate cancer, according to the clinical domain. This file describes the full list of selected QI for prostate cancer. (PDF 142 kb)12885_2018_4604_MOESM1_ESM.pdf
Arndt V, Feller A, Hauri D, Heusser R, Junker C, Kuehni C, Lorez M, Pfeiffer V, Schindler M. Schweizerischer Krebsbericht 2015. Stand und Entwicklungen. Neuchâtel: Office féderal de la statistique (OFS); 2016.
National Institute for Cancer Epidemiology and Registration (NICER). http://www.nicer.org/. 2016. Accessed July 2017.
Parkin DM, Chen VW, Ferlay J, Galceran J, Storm HH, Whelan SL. Comparability and quality control in cancer registration. IARC technical report no 19. Lyon: IARC; 2004.
Tyczynski JE, Démaret E, Parkin DM. Standards and guidelines for cancer registration in Europe. The ENCR recommendations. Volume 1. IARC Technical Publication n. 40. Lyon: IARC; 2003.
Eble JNSG, Epstein J, Sesterhenn I. Pathology and Genetics of Tumours of the Urinary System and Male Genital Organs. 3rd ed. Lyon: IARCPress; 2004.
Edge SB, Byrd DR, Carducci MA, Compton CC. AJCC Cancer staging manual. 7th ed. New York: Springer-Verlag; 2010.
Ferlay J, Burkhard C, Whelan S, Parkin DM. Check and conversion programs for Cancer registries (IARC/IACR tools for Cancer registries). IARC technical report no. 42. Lyon: IARC; 2005.
Martos C, Crocetti E, Visser O, Rous B. Cancer Data Quality Checks Working Group: A proposal on cancer data quality check: one common procedure for European cancer registries. Luxembourg: Publications Office of the European Union; 2014.
European Commission Joint Research Centre: JRC-ENCR quality check software, version 1.7.1. Available from: https://www.encr.eu/tools-for-registries; 2016. Accessed July 2017.
Bordoni A, Spitale A, Ortelli L, Mazzola P, Peverelli S: Registro cantonale dei tumori http://www.ti.ch/cancer. 2017. Accessed July 2017.
Bianchi V, Spitale A, Ortelli L and the QC3 CRC Working Group. Quality indicators of clinical cancer care (QC3) in colorectal cancer. BMJ Open. 2013; https://doi.org/10.1136/bmjopen-2013-002818.
Srigley JR, Humphrey PA, Amin MB, Chang SS, Egevad L, Epstein JI, Grignon DJ, McKiernan JM, Montironi R, Renshaw AA, et al. Protocol for the examination of specimens from patients with carcinoma of the prostate gland. Arch Pathol Lab Med. 2009;133(10):1568–76.
Horwick A, Parker C, Bangma CH, Kataya V. Prostate Cancer: ESMO clinical practice guidelines for diagnosis, treatment and follow-up. Ann Oncol. 2010;21:v129–33. CrossRef
Stättin P, Sandin F, Robinson D, Franck Lissbrant I, Hjälm Eriksson M. Prostate cancer. In: Report from the national prostate cancer register 2015. Uppsala Örebro: Regionalt cancercentrumm. 2016; http://npcr.se/rapporter/nationella-arsrapporter/. Accessed on July 2017.
Lorez M, Bordoni A, Bouchardy C, Buillard JP, Camey B, Dehler S, Frick H, Konzelmann I, Maspoli M, Mousavi SM, et al. Evaluation of completeness of case ascertainment in Swiss cancer registration. Eur J Cancer Prev. 2017;26:139–46.
Mohler JL, Armstrong AJ, Higano C, Kantoff PW, Plimack ER. Prostate cancer. In: NCCN clincal practice guidelines in oncology (NCCN guidelines). Natl Compr Canc Netw. 2011; http://www.nccn.org. Accessed on January 2011.
Gomez-Veiga F, Rodriguez-Antolin A, Minana B, Hernandez C, Suarez JF, Fernandez-Gomez JM, Unda M, Burgos J, Alcaraz A, Rodriguez P, et al. Diagnosis and treatment for clinically localized prostate cancer. Adherence to the European Association of Urology clinical guidelines in a nationwide population-based study - GESCAP group. Actas Urol Esp. 2017;
Amin M, Boccon-Gibod L, Egevad LL. Prognostic and predictive factors and reporting of prostate carcinoma in prostate needle biopsy specimens. (2005 WHO-sponseored international consultation consensus). Scand J Urol Nephrol. 2004;2004:20–33.
Bubendorf L, Diener PA. Fleischmann A, Heilemariam S, Lehr A. Prostate. In: Recommandations pour la qualité SSPath. Societé Suisse de Pathologie. 2011. http://sgpath.ch/assurance-de-la-qualite/. Accessed on August 2013.
Idowu MO, Bekeris LG, Raab S, Ruby SG, Nakhleh RE. Adequacy of surgical pathology reporting of cancer: a College of American Pathologists Q-probes study of 86 institutions. Arch Pathol Lab Med. 2010;134:969–74. PubMed
Hager B, Kraywinkel K, Keck B, Katalinic A, Meyer M, Zeissig SR, Stabenow R, Froehner M, Huber J. Integrated prostate cancer centers might cause an overutilization of radiotherapy for low-risk prostate cancer: a comparison of treatment trends in the United States and Germany from 2004 to 2011. Radiother Oncol. 2015;115:90–5. CrossRefPubMed
Mottet N, Bellmunt J, Briers E, Van der Bergh RCN, Bolla M, Van Casteren NJ, Cornford P, Culine S, Joniau S, Lam T, et al: Guidelines on Prostate Cancer. Available from https://uroweb.org/wp-content/uploads/09-Prostate-Cancer_LR.pdf (accessed on Juny 2017). European Association of Urology 2015. Accessed July 2017.
Roach M 3rd, Bae K, Speight J, Wolkov HB, Rubin P, Lee RJ, Lawton C, Valicenti R, Grignon D, Pilepich MV. Short-term neoadjuvant androgen deprivation therapy and external-beam radiotherapy for locally advanced prostate cancer: long-term results of RTOG 8610. J Clin Oncol. 2008;26:585–91. CrossRefPubMed
Chin JL, Srigley J, Mayhew LA, Rumble RB, Crossley C, Hunter A, Fleshner N, Bora B, McLeod R, McNair S, et al. Guideline for optimization of surgical and pathological quality performance for radical prostatectomy in prostate cancer management: evidentiary base. Can Urol Assoc J. 2010;4:13–25. CrossRefPubMedPubMedCentral
Danish Prostate Cancer (DAPROCA) data Annual Report 2014 (online). Available from https://www.sundhed.dk/content/cms/86/15686_daproca_%C3%A5rsrapport-2014_kommenteret_20150521final.pdf. Accessed July 2017.
Kamecki K, Biedka M, Makarewicz R, Siekiera J. Indications for postoperative radiotherapy in patients with prostate cancer after surgery with positive surgical margins. Contemp Oncol (Pozn). 2013;17:383–8.
Zietman AL, Bae K, Slater JD, Shipley WU, Efstathiou JA, Coen JJ, Bush DA, Lunt M, Spiegel DY, Skowronski R, et al. Randomized trial comparing conventional-dose with high-dose conformal radiation therapy in early-stage adenocarcinoma of the prostate: long-term results from proton radiation oncology group/american college of radiology 95-09. J Clin Oncol. 2010;28:1106–11. CrossRefPubMedPubMedCentral
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