Skip to main content
main-content

01.06.2015 | Ausgabe 6/2015

Surgical Endoscopy 6/2015

Quality of D2 lymphadenectomy for advanced gastric cancer: is laparoscopic-assisted distal gastrectomy as effective as open distal gastrectomy?

Zeitschrift:
Surgical Endoscopy > Ausgabe 6/2015
Autoren:
Canrong Lu, Sixin Zhou, Zheng Peng, Lin Chen
Wichtige Hinweise
Canrong Lu and Sixin Zhou contributed equally to this work.

Abstract

Objective

To determine by meta-analysis, whether D2 lymphadenectomy at laparoscopic-assisted distal gastrectomy (LADG) is as effective as that during open distal gastrectomy (ODG) for patients with advanced gastric cancer (AGC).

Data sources and review methods

All clinical trials that compared laparoscopic with open D2 lymphadenectomy for AGC published in English from January 1995 to June 2013 were identified in PubMed, Embase, Web of Science, and Cochrane library searches. A modified scale was used to assess the quality of the literature. We analyzed the number of harvested lymph nodes (HLNs), body mass index (BMI), tumor size, serosa invasion status, and positive lymph node rate. Meta-analyses were performed using weighted mean differences (WMD) for continuous variables, and risk differences (RD) or odds ratios (OR) for dichotomous variables.

Results

No eligible randomized trials were identified, but eight non-randomized trials were analyzed. In the pooled data of 677 patients who underwent LADG and 687 ODG, there were no significant differences the number of HLN (WMD: −0.98, 95 % confidence interval, CI −3.21 to 1.26), BMI (WMD: −1.20, 95 % CI −2.64 to 0.24), tumor size (WMD: −0.30, 95 % CI −0.65 to 0.05), serosa invasion status (RD: 0.04, 95 % CI −0.03 to 0.11), and positive lymph node rate (OR: 0.66, 95 % CI −0.44 to 1.01) between the groups.

Conclusion

Our findings suggest that for patients with comparable BMI and tumor status, surgical technique did not significantly influence the number of HLNs, suggesting that D2 lymphadenectomy performed laparoscopically is as effective as an open procedure in AGC.

Bitte loggen Sie sich ein, um Zugang zu diesem Inhalt zu erhalten

★ PREMIUM-INHALT
e.Med Interdisziplinär

Mit e.Med Interdisziplinär erhalten Sie Zugang zu allen CME-Fortbildungen und Fachzeitschriften auf SpringerMedizin.de. Zusätzlich können Sie eine Zeitschrift Ihrer Wahl in gedruckter Form beziehen – ohne Aufpreis.

Weitere Produktempfehlungen anzeigen
Literatur
Über diesen Artikel

Weitere Artikel der Ausgabe 6/2015

Surgical Endoscopy 6/2015 Zur Ausgabe
  1. Sie können e.Med Chirurgie 14 Tage kostenlos testen (keine Print-Zeitschrift enthalten). Der Test läuft automatisch und formlos aus. Es kann nur einmal getestet werden.

Neu im Fachgebiet Chirurgie

Mail Icon II Newsletter

Bestellen Sie unseren kostenlosen Newsletter Update Chirurgie und bleiben Sie gut informiert – ganz bequem per eMail.

Bildnachweise