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Erschienen in:

01.03.2024

Quantitative comparison of the isolation lesions between conventional- and larger-sized visually guided laser balloon ablation

verfasst von: Takashi Yamasaki, Ken Kakita, Misun Pak, Tetsuhisa Hattori

Erschienen in: Journal of Interventional Cardiac Electrophysiology | Ausgabe 5/2024

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Abstract

Background

The importance of a wider circumferential isolation of the pulmonary veins (PV), which includes a large portion of the left atrial posterior wall (LAPW), has been suggested in several studies. However, the extended isolation area using a larger inflated visually guided laser balloon (VGLB) ablation remains to be elucidated.

Methods

Seventy-eight patients with atrial fibrillation (AF) who underwent VGLB ablation were enrolled in this prospective study. An electroanatomic map of the left atrium was obtained before and after PV isolation (PVI) using a conventional-sized VGLB. The isolation areas were extended by the largest-sized VGLB ablation and remapped in the same manner. After the ablation, isolation areas were calculated with CARTO-3 system. The one-year atrial arrhythmia (Ata) recurrence was assessed. 

Results

The largest-sized VGLB ablation yielded statistically greater areas of isolation in left-sided PV antrum (PVA) (11.5 ± 2.3 cm2 vs. 15.9 ± 3.5 cm2, P < .001) and right-sided PVA (14.2 ± 3.3 cm2 vs. 20.6 ± 4.4 cm2, P < .001) than the conventional-sized VGLB. Further, non-ablated LAPW (12.3 ± 4.4 cm2 vs. 7.8 ± 3.9 cm2, P < .001) was significantly reduced after largest-sized VGLB ablation, compared to the conventional-sized VGLB ablation. The one-year Ata freedom was 83.7% in patients with paroxysmal AF and 96.4% in those with persistent AF.

Conclusion

The largest-sized VGLB ablation technique can create a significantly wider isolation area of PVA and debulk a large amount of LAPW than the conventional-sized VGLB ablation. The one-year outcome was similarly high in paroxysmal and persistent AF.

Graphical Abstract

Literatur
1.
Zurück zum Zitat Hindricks G, Potpara T, Dagres N, Arbelo E, Bax JJ, Blomström-Lundqvist C. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2021;42:373–498.CrossRefPubMed Hindricks G, Potpara T, Dagres N, Arbelo E, Bax JJ, Blomström-Lundqvist C. 2020 ESC Guidelines for the diagnosis and management of atrial fibrillation developed in collaboration with the European Association for Cardio-Thoracic Surgery (EACTS). Eur Heart J. 2021;42:373–498.CrossRefPubMed
2.
Zurück zum Zitat Dukkipati SR, Neuzil P, Kautzner J, Petru J, Wichterle D, Skoda J, Cihak R, Peichl P, Dello Russo A, Pelargonio G, Tondo C, Natale A, Reddy VY. The durability of pulmonary vein isolation using the visually guided laser balloon catheter: multicenter results of pulmonary vein remapping studies. Heart Rhythm. 2012;9:919–25.CrossRefPubMed Dukkipati SR, Neuzil P, Kautzner J, Petru J, Wichterle D, Skoda J, Cihak R, Peichl P, Dello Russo A, Pelargonio G, Tondo C, Natale A, Reddy VY. The durability of pulmonary vein isolation using the visually guided laser balloon catheter: multicenter results of pulmonary vein remapping studies. Heart Rhythm. 2012;9:919–25.CrossRefPubMed
3.
Zurück zum Zitat Aryana A, Baker JH, Espinosa Ginic MA, Pujara DK, Bowers MR, O’Neill PG, Ellenbogen KA, Biase LD, Avila A, Natale A. Posterior wall isolation using the cryoballoon in conjunction with pulmonary vein ablation is superior to pulmonary vein isolation alone in patients with persistent atrial fibrillation: a multicenter experience. Heart Rhythm. 2018;15:1121–9.CrossRefPubMed Aryana A, Baker JH, Espinosa Ginic MA, Pujara DK, Bowers MR, O’Neill PG, Ellenbogen KA, Biase LD, Avila A, Natale A. Posterior wall isolation using the cryoballoon in conjunction with pulmonary vein ablation is superior to pulmonary vein isolation alone in patients with persistent atrial fibrillation: a multicenter experience. Heart Rhythm. 2018;15:1121–9.CrossRefPubMed
4.
Zurück zum Zitat Ahn J, Shin DG, Han SJ, Lim HE. Does isolation of the left atrial posterior wall using cryoballoon ablation improve clinical outcomes in patients with persistent atrial fibrillation? A Prospect Random Controlled Trial Eur. 2022;24:1093–101. Ahn J, Shin DG, Han SJ, Lim HE. Does isolation of the left atrial posterior wall using cryoballoon ablation improve clinical outcomes in patients with persistent atrial fibrillation? A Prospect Random Controlled Trial Eur. 2022;24:1093–101.
5.
Zurück zum Zitat Nishimura T, Yamauchi Y, Aoyagi H, Tsuchiya Y, Shigeta T, Nakamura R, Hirao T, Sasano T, Hirao K. The clinical impact of the left atrial posterior wall lesion formation by the cryoballoon application for persistent atrial fibrillation: feasibility and clinical implications. J Cardiovasc Electrophysiol. 2019;30:805–14.CrossRefPubMed Nishimura T, Yamauchi Y, Aoyagi H, Tsuchiya Y, Shigeta T, Nakamura R, Hirao T, Sasano T, Hirao K. The clinical impact of the left atrial posterior wall lesion formation by the cryoballoon application for persistent atrial fibrillation: feasibility and clinical implications. J Cardiovasc Electrophysiol. 2019;30:805–14.CrossRefPubMed
6.
Zurück zum Zitat Benito EM, Cabanelas N, Nuñez-Garcia M, Alarcón F, Figueras I, Ventura RM, Soto-Iglesias D, Guasch E, Prat-Gonzalez S, Perea RJ, Borràs R, Butakof C, Camara O, Bisbal F, Arbelo E, Tolosana JM, Brugada J, Berruezo A, Mont L. Preferential regional distribution of atrial fibrosis in posterior wall around left inferior pulmonary vein as identified by late gadolinium enhancement cardiac magnetic resonance in patients with atrial fibrillation. Europace. 2018;20:1959–65.CrossRefPubMed Benito EM, Cabanelas N, Nuñez-Garcia M, Alarcón F, Figueras I, Ventura RM, Soto-Iglesias D, Guasch E, Prat-Gonzalez S, Perea RJ, Borràs R, Butakof C, Camara O, Bisbal F, Arbelo E, Tolosana JM, Brugada J, Berruezo A, Mont L. Preferential regional distribution of atrial fibrosis in posterior wall around left inferior pulmonary vein as identified by late gadolinium enhancement cardiac magnetic resonance in patients with atrial fibrillation. Europace. 2018;20:1959–65.CrossRefPubMed
7.
Zurück zum Zitat Lim HS, Hocini M, Dubois R, Denis A, Derval N, Zellerhof S, Yamashita S, Berte B, Mahida S, Komatsu Y, Daly M, Jesel L, Pomier C, Meillet V, Amraoui S, Shah AJ, Cochet H, Sacher F, Jaïs P, Haïssaguerre M. Complexity and distribution of drivers in relation to duration of persistent atrial fibrillation. J Am Coll Cardiol. 2017;69:1257–69.CrossRefPubMed Lim HS, Hocini M, Dubois R, Denis A, Derval N, Zellerhof S, Yamashita S, Berte B, Mahida S, Komatsu Y, Daly M, Jesel L, Pomier C, Meillet V, Amraoui S, Shah AJ, Cochet H, Sacher F, Jaïs P, Haïssaguerre M. Complexity and distribution of drivers in relation to duration of persistent atrial fibrillation. J Am Coll Cardiol. 2017;69:1257–69.CrossRefPubMed
8.
Zurück zum Zitat Schmidt B, Neuzil P, Luik A, Asensi JO, Schrickel JW, Deneke T, Bordignon S, Petru J, Merkel M, Sediva L, Klostermann A, Perrotta L, Cano O, Chun JKR. Laser balloon or wide-area circumferential irrigated radiofrequency ablation for persistent atrial fibrillation: a multicenter prospective randomized study. Circ Arrhythm Electrophysiol. 2017;10(14):e005767.CrossRefPubMed Schmidt B, Neuzil P, Luik A, Asensi JO, Schrickel JW, Deneke T, Bordignon S, Petru J, Merkel M, Sediva L, Klostermann A, Perrotta L, Cano O, Chun JKR. Laser balloon or wide-area circumferential irrigated radiofrequency ablation for persistent atrial fibrillation: a multicenter prospective randomized study. Circ Arrhythm Electrophysiol. 2017;10(14):e005767.CrossRefPubMed
9.
Zurück zum Zitat Kiuchi K, Kircher S, Watanabe N, Gaspar T, Rolf S, Arya A, Piorkowski C, Hindricks G, Sommer P. Quantitative analysis of isolation area and rhythm outcome in patients with paroxysmal atrial fibrillation after circumferential pulmonary vein antrum isolation using the pace-and-ablate technique. Circ Arrhythm Electrophysiol. 2012;5(4):667–75.CrossRefPubMed Kiuchi K, Kircher S, Watanabe N, Gaspar T, Rolf S, Arya A, Piorkowski C, Hindricks G, Sommer P. Quantitative analysis of isolation area and rhythm outcome in patients with paroxysmal atrial fibrillation after circumferential pulmonary vein antrum isolation using the pace-and-ablate technique. Circ Arrhythm Electrophysiol. 2012;5(4):667–75.CrossRefPubMed
10.
Zurück zum Zitat Chun JKR, Bordignon S, Last J, Mayer L, Tohoku S, Zanchi S, Bianchini L, Bologna F, Nagase T, Urbanek L, Chen S, Schmidt B. Cryoballoon versus laserballoon: insights from the first prospective randomized balloon trial in catheter ablation of atrial fibrillation. Circ Arrhythm Electrophysiol. 2021;14:e009294.CrossRefPubMed Chun JKR, Bordignon S, Last J, Mayer L, Tohoku S, Zanchi S, Bianchini L, Bologna F, Nagase T, Urbanek L, Chen S, Schmidt B. Cryoballoon versus laserballoon: insights from the first prospective randomized balloon trial in catheter ablation of atrial fibrillation. Circ Arrhythm Electrophysiol. 2021;14:e009294.CrossRefPubMed
11.
Zurück zum Zitat Kenigsberg DN, Martin N, Lim HW, Kowalski M, Ellenbogen KA. Quantification of the cryoablation zone demarcated by pre- and postprocedural electroanatomic mapping in patients with atrial fibrillation using the 28-mm second-generation cryoballoon. Heart Rhythm. 2015;12:283–90.CrossRefPubMed Kenigsberg DN, Martin N, Lim HW, Kowalski M, Ellenbogen KA. Quantification of the cryoablation zone demarcated by pre- and postprocedural electroanatomic mapping in patients with atrial fibrillation using the 28-mm second-generation cryoballoon. Heart Rhythm. 2015;12:283–90.CrossRefPubMed
12.
Zurück zum Zitat Perrotta L, Konstantinou A, Bordignon S, Fuernkranz A, Dugo D, Chun JKR, Schmidt B. What is the acute antral lesion size after pulmonary vein isolation using different balloon ablation technologies? Circ J. 2017;81:172–9.CrossRefPubMed Perrotta L, Konstantinou A, Bordignon S, Fuernkranz A, Dugo D, Chun JKR, Schmidt B. What is the acute antral lesion size after pulmonary vein isolation using different balloon ablation technologies? Circ J. 2017;81:172–9.CrossRefPubMed
13.
Zurück zum Zitat Nagase T, Bordignon S, Perrotta L, Bologna F, Tsianakas N, Chen S, et al. Analysis of procedural data of pulmonary vein isolation for atrial fibrillation with the second-generation laser balloon. Pacing Clin Electrophysiol. 2019;42:837–45. Nagase T, Bordignon S, Perrotta L, Bologna F, Tsianakas N, Chen S, et al. Analysis of procedural data of pulmonary vein isolation for atrial fibrillation with the second-generation laser balloon. Pacing Clin Electrophysiol. 2019;42:837–45.
14.
Zurück zum Zitat Heeger CH, Phan HL, Meyer-Saraei R, Fink T, Sciacca V, Liosis S, et al. Second-generation visually guided laser balloon ablation system for pulmonary vein isolation: learning curve, safety and efficacy-the MERLIN registry. Circ J. 2019;83(12):2443–51. Heeger CH, Phan HL, Meyer-Saraei R, Fink T, Sciacca V, Liosis S, et al. Second-generation visually guided laser balloon ablation system for pulmonary vein isolation: learning curve, safety and efficacy-the MERLIN registry. Circ J. 2019;83(12):2443–51.
15.
Zurück zum Zitat Schmidt B, Petru J, Chun JKR, Sediva L, Bordignon S, Chen S, et al. Pivotal study of a novel motor-driven endoscopic ablation system. Circ Arrhythm Electrophysiol. 2021;14:e009544. Schmidt B, Petru J, Chun JKR, Sediva L, Bordignon S, Chen S, et al. Pivotal study of a novel motor-driven endoscopic ablation system. Circ Arrhythm Electrophysiol. 2021;14:e009544.
16.
Zurück zum Zitat Heeger CH, Tiemeyer CM, Phan HL, Meyer-Saraei R, Fink T, Sciacca V, et al. Rapid pulmonary vein isolation utilizing the third-generation laser balloon - The PhoeniX registry. Int J Cardiol Heart Vasc. 2020;29:100576. Heeger CH, Tiemeyer CM, Phan HL, Meyer-Saraei R, Fink T, Sciacca V, et al. Rapid pulmonary vein isolation utilizing the third-generation laser balloon - The PhoeniX registry. Int J Cardiol Heart Vasc. 2020;29:100576.
17.
Zurück zum Zitat Leung LWM, Akhtar Z, Sheppard MN, Auguste JL, Hayat J, Gallagher MM. Preventing esophageal complications from atrial fibrillation ablation: a review. Heart Rhythm. 2021;O2(2):651–64.CrossRef Leung LWM, Akhtar Z, Sheppard MN, Auguste JL, Hayat J, Gallagher MM. Preventing esophageal complications from atrial fibrillation ablation: a review. Heart Rhythm. 2021;O2(2):651–64.CrossRef
18.
Zurück zum Zitat Metzner A, Schmidt B, Fuernkranz A, Wissner E, Tilz RR, Koester I, Konstantinidou M, Rillig A, Yoshiga Y, Mathew S, Ouyang F, Kuck KH. Esophageal temperature change and esophageal thermal lesions after pulmonary vein isolation using the novel endoscopic ablation system. Heart Rhythm. 2011;8:815–20.CrossRefPubMed Metzner A, Schmidt B, Fuernkranz A, Wissner E, Tilz RR, Koester I, Konstantinidou M, Rillig A, Yoshiga Y, Mathew S, Ouyang F, Kuck KH. Esophageal temperature change and esophageal thermal lesions after pulmonary vein isolation using the novel endoscopic ablation system. Heart Rhythm. 2011;8:815–20.CrossRefPubMed
19.
Zurück zum Zitat Sánchez-Quintana D, Cabrera JA, Climent V, Farré J, Mendonça MC, Ho SY. Anatomic relations between the esophagus and left atrium and relevance for ablation of atrial fibrillation. Circulation. 2005;112:1400–5.CrossRefPubMed Sánchez-Quintana D, Cabrera JA, Climent V, Farré J, Mendonça MC, Ho SY. Anatomic relations between the esophagus and left atrium and relevance for ablation of atrial fibrillation. Circulation. 2005;112:1400–5.CrossRefPubMed
20.
Zurück zum Zitat Matsunaga LY, Egami Y, Nakamura H, Matsuhiro Y, Yasumoto K, Tsuda M, Tanaka A, Okamoto N, Yano M, Shutta R, Sakata Y, Nishino M, Tanouchi J. Effect of the balloon size on lesion formation during visually guided laser balloon ablation in an in vitro model. Circ J. 2021;85:1394–9.CrossRef Matsunaga LY, Egami Y, Nakamura H, Matsuhiro Y, Yasumoto K, Tsuda M, Tanaka A, Okamoto N, Yano M, Shutta R, Sakata Y, Nishino M, Tanouchi J. Effect of the balloon size on lesion formation during visually guided laser balloon ablation in an in vitro model. Circ J. 2021;85:1394–9.CrossRef
21.
Zurück zum Zitat Nair GM, Birnie DH, Nery PB, Redpath CJ, Sarrazin J-F, Roux J-F, et al. Standard vs augmented ablation of paroxysmal atrial fibrillation for reduction of atrial fibrillation recurrence: the AWARE randomized clinical trial. JAMA Cardiol. 2023;8:475–83. Nair GM, Birnie DH, Nery PB, Redpath CJ, Sarrazin J-F, Roux J-F, et al. Standard vs augmented ablation of paroxysmal atrial fibrillation for reduction of atrial fibrillation recurrence: the AWARE randomized clinical trial. JAMA Cardiol. 2023;8:475–83.
22.
Zurück zum Zitat Sousa PA, Barra S, Saleiro C, Khoueiry Z, Adao L, Primo J, et al. Ostial vs. wide area circumferential ablation guided by the ablation index in paroxysmal atrial fibrillation. Europace. 2023;25:1–9.CrossRef Sousa PA, Barra S, Saleiro C, Khoueiry Z, Adao L, Primo J, et al. Ostial vs. wide area circumferential ablation guided by the ablation index in paroxysmal atrial fibrillation. Europace. 2023;25:1–9.CrossRef
23.
Zurück zum Zitat Calkins H, Hindricks G, Cappato R, et al. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Heart Rhythm. 2017;14(10):e275–444.CrossRefPubMedPubMedCentral Calkins H, Hindricks G, Cappato R, et al. 2017 HRS/EHRA/ECAS/APHRS/SOLAECE expert consensus statement on catheter and surgical ablation of atrial fibrillation. Heart Rhythm. 2017;14(10):e275–444.CrossRefPubMedPubMedCentral
24.
Zurück zum Zitat Kistler PM, Chieng D. Persistent atrial fibrillation in the setting of pulmonary vein isolation- where to next? J Cardiovasc Electrophysiol. 2020;31(7):1857–60.CrossRefPubMed Kistler PM, Chieng D. Persistent atrial fibrillation in the setting of pulmonary vein isolation- where to next? J Cardiovasc Electrophysiol. 2020;31(7):1857–60.CrossRefPubMed
25.
Zurück zum Zitat Yamashita S, Takigawa M, Denis A, Derval N, Sakamoto Y, Masuda M, et al. Pulmonary vein-gap re-entrant atrial tachycardia following atrial fibrillation ablation: an electrophysiological insight with high-resolution mapping. Europace. 2019;21:1039–47.CrossRefPubMed Yamashita S, Takigawa M, Denis A, Derval N, Sakamoto Y, Masuda M, et al. Pulmonary vein-gap re-entrant atrial tachycardia following atrial fibrillation ablation: an electrophysiological insight with high-resolution mapping. Europace. 2019;21:1039–47.CrossRefPubMed
Metadaten
Titel
Quantitative comparison of the isolation lesions between conventional- and larger-sized visually guided laser balloon ablation
verfasst von
Takashi Yamasaki
Ken Kakita
Misun Pak
Tetsuhisa Hattori
Publikationsdatum
01.03.2024
Verlag
Springer US
Erschienen in
Journal of Interventional Cardiac Electrophysiology / Ausgabe 5/2024
Print ISSN: 1383-875X
Elektronische ISSN: 1572-8595
DOI
https://doi.org/10.1007/s10840-024-01738-6

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