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Erschienen in: European Spine Journal 2/2008

01.09.2008 | Case Report

Radiculopathy due to malignant melanoma in the sacrum with unknown primary site

verfasst von: Kenichiro Kakutani, Minoru Doita, Kotaro Nishida, Hiroshi Miyamoto, Masahiro Kurosaka

Erschienen in: European Spine Journal | Sonderheft 2/2008

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Abstract

Melanoma is an interesting tumor, showing the appearance of metastasis without any trace of its primary lesion. To report a very rare case of malignant melanoma in the sacrum with unknown primary origin. The authors present a case of a 52-year-old man who was admitted with increasing lower back, left buttock, and left lower extremity pain, and dysuria. Plain radiograph, computed tomography scan, and magnetic resonance imaging revealed a destructive lesion in the sacrum and left ilium, which infiltrated the spinal canal and sacroiliac joint. The tumor cells were immunoreactive for HMB-45. The pathological diagnosis was malignant melanoma. No obvious primary malignant melanoma was detected on the skin surface, on the oral or anal mucosa, or in the fundus oculi. Following radiotherapy and chemotherapy, the severe buttock pain disappeared and the patient was able to walk without impediment. However the patient died nine months after initial diagnosis. Malignant melanoma in the sacrum with an unknown primary site, showing S1 radiculopathy is reported for the first time. The melanoma could have been a metastatic tumor of the sacrum, although the primary site was not detected. The incidence of primary melanoma is increasing faster than any other cancer. Thus treatment of patients with spinal metastasis of melanoma is an important challenge for orthopedic surgeons.
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Metadaten
Titel
Radiculopathy due to malignant melanoma in the sacrum with unknown primary site
verfasst von
Kenichiro Kakutani
Minoru Doita
Kotaro Nishida
Hiroshi Miyamoto
Masahiro Kurosaka
Publikationsdatum
01.09.2008
Verlag
Springer-Verlag
Erschienen in
European Spine Journal / Ausgabe Sonderheft 2/2008
Print ISSN: 0940-6719
Elektronische ISSN: 1432-0932
DOI
https://doi.org/10.1007/s00586-007-0561-1

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