Breast reduction is a common cosmetic surgical procedure to reduce the size of the breast and to overcome discomfort caused by oversized, ill-shaped and hanging breasts [
1]. Although most complications can be overcome with proper selection of the procedure and with gentle tissue handling, reported percentages of complications are as high as 53% [
2‐
4]. The most common complication is delayed wound healing, and other complications include hematoma, fat necrosis, nipple necrosis, cellulitis and fungal dermatitis [
4‐
6]. Hypertrophy is common after inferior pedicle breast reduction in the inframammary scar, and 15% of all scars are reported to be thick, itchy or uncomfortable [
2]. The assumption is that quality of scarring may be improved when wound healing is effective, without complications. Negative pressure wound therapy (NPWT) refers to the controlled application of sub-atmospheric pressure to promote wound healing and has been applied in a wide array of acute and chronic wounds [
7‐
9]. Over the years, clinical success of NPWT encouraged specialists to apply the technique to closed surgical incisions. It serves as a preventative measure after high-risk procedures, mainly in trauma and cardiothoracic surgery, or in patients with multiple comorbidities and/or risk factors such as obesity and use of steroids [
10,
11]. Stannard et al. [
12,
13] published two studies on different high-risk skeletal traumas in which they concluded that there were significantly less infections and cases of dehiscence in the NPWT group compared to the sites treated with standard care. A recent development in the field of NPWT is a portable disposable system. An early study evaluating the performance and clinical benefits of the system showed promising results [
14].
A study was developed including 32 patients undergoing bilateral reduction mammoplasty, to evaluate the effectiveness of post-surgery incision treatment comparing a portable disposable NPWT system with standard care, using fixation strips. Patients were followed up to 365 days post-surgery.