The online version of this article (https://doi.org/10.1186/s12876-018-0740-z) contains supplementary material, which is available to authorized users.
The original article has been corrected: authors Glauce Hiromi Yonamine and Carla Aline Fernandes Satiro have had their names corrected.
A correction to this article is available online at https://doi.org/10.1186/s12876-018-0757-3.
Compliance with a gluten-free diet (GFD) is difficult at all ages but particularly for teenagers due to social, cultural, economic, and practical pressures. The multidisciplinary team responsible for the treatment of patients with celiac disease and give support to their parents plays a special role on strengthening GFD and assessing the nutritional and physical health.
A cross-sectional and retrospective study including patients under 20 years of age, with biopsy-confirmed CD, followed regularly at the Department of Pediatrics, Division of Gastroenterology, Hospital das Clínicas, University of Sao Paulo, School of Medicine, Sao Paulo, Brazil, were surveyed using a questionnaire and serologic test applied between November 2011 and February 2012. A retrospective chart review of these patients was performed to collect the anthropometric data along with the results of the serologic test performed at the time of diagnosis and after at least 1 year of treatment with a GFD.
We evaluated 35 patients aged between 2.4 and 19.9 years. Of these 68.6% were female, 88.6% had the typical form of the disease and 51.4% had other comorbidities. The mean age at diagnosis was 5.4 years. Despite dietary guidance, 20% reported non-adherence to the diet. Most children recovered the weight and height deficit after 5 years of treatment, and in some children, excessive weight gain became a concern.
The majority of transgressions occurred intentionally at home or at parties. There was a risk of excessive weight gain, especially in the first two years of treatment. More alternatives and easier access to low cost gluten-free foods, increasing the discussion about the benefits of adhering to a GFD among patients, families, and the general population, besides the acquisition of self-management skills, are crucial to fostering independent children and adolescents who have the knowledge and tools to manage life with CD.
Additional file 1: Questionnaire for assessment of adherence to the treatment of patients with Celiac Disease. Questionnaire constructed for this study comprising two open questions on social events and difficulties with the GFD, and closed questions about food routine, awareness, adherence and difficulties regarding the GFD. (DOC 75 kb)12876_2018_740_MOESM1_ESM.doc
Fasano A, Araya M, Bhatnagar S, Cameron D, Catassi C, Dirks M, Mearin ML, Ortigosa L, Phillips A; Celiac Disease Working Group, FISPGHAN. Federation Of international societies of pediatric gastroenterology, hepatology, and nutrition consensus report on celiac disease. J Pediatr Gastroenterol Nutr 2008;47(2):214–219.
Oliveira RP, Sdepanian VL, Barreto JA, Cortez AJ, Carvalho FO, Bordin JO, de Camargo Soares MA, da Silva Patrício FR, Kawakami E, de Morais MB, Fagundes-Neto U. High prevalence of celiac disease in Brazilian blood donor volunteers based on screening by IgA antitissue transglutaminase antibody. Eur J Gastroenterol Hepatol. 2007;19(1):43–9. CrossRefPubMed
Alencar ML, Ortiz-Agostinho CL, Nishitokukado L, Damião AO, Abrantes-Lemos CP, Leite AZ, Td B, Chamone Dde A, Silva ME, Giannella-Neto D, Sipahi AM. Prevalence of celiac disease among blood donors in São Paulo: the most populated city in Brazil. Clinics (Sao Paulo). 2012;67(9):1013–8. CrossRef
Pereira MA, Ortiz-Agostinho CL, Nishitokukado I, Sato MN, Damião AO, Alencar ML, Abrantes-Lemos CP, Cançado EL, de Brito T, Ioshii SO, Valarini SB, Sipahi AM. Prevalence of celiac disease in an urban area of Brazil with predominantly European ancestry. World J Gastroenterol. 2006, 28;12(40):6546–50.
Valitutti F, Trovato CM, Montuori M, Cucchiara S. Pediatric Celiac Disease: Follow-Up in the Spotlight. Adv Nutr. 2017, 15;8(2):356–361.
Husby S, Koletzko S, Korponay-Szabó IR, Mearin ML, Phillips A, Shamir R, Troncone R, Giersiepen K, Branski D, Catassi C, Lelgeman M, Mäki M, Ribes-Koninckx C, Ventura A, Zimmer KP; ESPGHAN working group on coeliac disease diagnosis.; ESPGHAN gastroenterology committee.; European Society for Pediatric Gastroenterology, hepatology, and nutrition. European Society for Pediatric Gastroenterology, Hepatology, and Nutrition guidelines for the diagnosis of coeliac disease.J Pediatr Gastroenterol Nutr 2012;54(1):136–160.
WHO Multicentre Growth Reference Study Group. WHO child growth standards: length/height-for-age, weight-for-age, weight-for-length, weight-for-height and body mass index-for-age: methods and development. Geneva: World Health Organization; 2006.
Bravo MF, Munõz FMP. Adherence and impact of gluten free diet in children with celiac disease. Rev Chil Pediatr. 2011;82(3):191–7.
Reilly NR, Aguilar K, Hassid BG, Cheng J, Defelice AR, Kazlow P, Bhagat G, Green PH. Celiac disease in normal-weight and overweight children: clinical features and growth outcomes following a gluten-free diet. J Pediatr Gastroenterol Nutr. 2011;53(5):528–31. PubMed
Moreno ML, Rodríguez-Herrera A, Sousa C, Comino I. Biomarkers to Monitor Gluten-Free Diet Compliance in Celiac Patients. Nutrients. 2017, 6;9(1), pii: E46..
Sdepanian VL, de Morais MB, Fagundes-Neto U. [Celiac disease: evaluation of compliance to gluten-free diet and knowledge of disease in patients registered at the Brazilian Celiac Association (ACA)]. Arq Gastroenterol 2001;38(4):232–239.
Hartman C, Hino B, Lerner A, et al. Bone quantitative ultrasound and boné mineral density in children with celiac disease. JPediatr Gastroenteorl Nutr. 2004;39:504–10. CrossRef
Bazzigaluppi E, Roggero P, Parma B, et al. Antibodies to recombinant human tissue-transglutaminase in coeliac disease: diagnostic effectiveness and decline pattern after gluten-free diet. Dig Liver Dis. 2006;38:98–102. PubMed
Byströn IM, Hollen E, Fälth-Magnusson K, Johansson A. Health-related quality of life in children and adolescents with celiac disease: from the perspectives of children and parents. Gastroenterol Res Pract. 2012;2012(986475)
Andreoli CS, Cortez APB, Sdepanian VL, Morais MB. Nutritional evaluation and food intake of celiac disease patients compliant or not with a gluten-free diet. Rev Nutr. Campinas. 2013;26(3):301–11.
- Rate and determinants of non-adherence to a gluten-free diet and nutritional status assessment in children and adolescents with celiac disease in a tertiary Brazilian referral center: a cross-sectional and retrospective study
Glauce Hiromi Yonamine
Carla Aline Fernandes Satiro
- BioMed Central
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