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Breast Cancer Research

Erschienen in:

01.06.2005 | Poster Presentation

Real-time PCR-based expression profiling of BRCA1-induced genes in primary breast tumors

verfasst von: B Gur, B Bozkurt, O Konu, S Seckin, IG Yulug

Erschienen in: Breast Cancer Research | Sonderheft 2/2005

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Excerpt

BRCA1 possesses a number of features common to transcriptional regulatory proteins, suggesting that it may regulate the expression of one or more downstream genes. It is important to determine which genes are transcriptionally influenced by BRCA1 in vivo to explain its role in tumor suppression and in cancer development. In our previous study, a BRCA1 overexpression system enabled us to define the genes whose expression levels were induced in MCF-7 breast cancer cells by using the PCR-dependent suppression subtractive hybridization technique [1]. …

Atalay A, Crook T, Ozturk M, Yulug IG: Identification of genes induced by BRCA1 in breast cancer cells. Biochem Biophys Res Commun. 2002, 299: 839-846. 10.1016/S0006-291X(02)02751-1.CrossRefPubMed

Eisen Laboratory. [http://rana.lbl.gov/EisenSoftware.htm]

Titel: Real-time PCR-based expression profiling of BRCA1-induced genes in primary breast tumors
verfasst von: B Gur
B Bozkurt
O Konu
S Seckin
IG Yulug
Publikationsdatum: 01.06.2005
Verlag: BioMed Central
Erschienen in: Breast Cancer Research / Ausgabe Sonderheft 2/2005
Elektronische ISSN: 1465-542X
DOI: https://doi.org/10.1186/bcr1149

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