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Clinical Journal of Gastroenterology
Erschienen in: Clinical Journal of Gastroenterology 6/2016

03.10.2016 | Clinical Review

Recent trends and future directions for the medical treatment of ulcerative colitis

verfasst von: Makoto Naganuma, Shinta Mizuno, Kosaku Nanki, Shinya Sugimoto, Takanori Kanai

Erschienen in: Clinical Journal of Gastroenterology | Ausgabe 6/2016

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Abstract

Recently, several medical treatments for ulcerative colitis (UC) have been developed, including 5-aminosalicylic acids (5-ASAs), corticosteroids, thiopurine, calcineurin inhibitors, and anti-tumor necrosis factor (TNF) α treatments. Treatment options including calcineurin inhibitors and anti-TNF treatment for refractory UC are discussed in this article. Furthermore, upcoming treatments are introduced, such as golimumab, vedolizumab, AJM300, tofacitinib. Budesonide foamwill be used as one treatment option in patients with distal colitis. Herbal medicine, such as Qing-Dai is also effective for active UC and may be useful for patients who are refractory to anti-TNFα treatments. In the near future, physicians will able to use many different treatments for UC patients. However, we should not forget 5-ASA and corticosteroids as the fundamental treatments for UC patients.
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Metadaten
Titel
Recent trends and future directions for the medical treatment of ulcerative colitis
verfasst von
Makoto Naganuma
Shinta Mizuno
Kosaku Nanki
Shinya Sugimoto
Takanori Kanai
Publikationsdatum
03.10.2016
Verlag
Springer Japan
Erschienen in
Clinical Journal of Gastroenterology / Ausgabe 6/2016
Print ISSN: 1865-7257
Elektronische ISSN: 1865-7265
DOI
https://doi.org/10.1007/s12328-016-0686-z

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