Skip to main content
Erschienen in: Archives of Gynecology and Obstetrics 6/2019

15.11.2019 | General Gynecology

Recurrence and prediction of abnormal uterine bleeding and re-intervention after initial hysteroscopic treatment: a retrospective cohort study

verfasst von: Silke F. G. Schaffrath, Janique R. J. Dreessen, Marlies Y. Bongers, Sander M. J. van Kuijk, Ben W. J. Mol, Josje Langenveld

Erschienen in: Archives of Gynecology and Obstetrics | Ausgabe 6/2019

Einloggen, um Zugang zu erhalten

Abstract

Purpose

To estimate the incidence of recurrence of complaints and repeated interventions after hysteroscopic treatment for abnormal uterine bleeding in premenopausal women and to determine potential predictors for re-intervention.

Methods

This is a retrospective cohort study in two secondary care centers in the Netherlands. We included 313 premenopausal women who underwent hysteroscopy for complaints of abnormal uterine bleeding and who had intrauterine pathology visualized at ultrasound. The intrauterine structure was hysteroscopically removed. These women were compared with women who had a hysteroscopy for abnormal uterine bleeding, but in whom hysteroscopy showed no abnormalities. We used Chi-squared test for categorical variables and independent-samples T test for continuous variables. p Values less than 0.05 were considered to indicate statistical significance.

Results

In total, 262 women had intrauterine pathology removed at hysteroscopy; 136 (52%) women had recurrence of complaints, while 101 women (39%) underwent re-intervention. Heavy menstrual bleeding at baseline and multiparity were predictive factors for recurrence of abnormal uterine bleeding and re-intervention. In the 51 women with abnormal uterine bleeding in whom hysteroscopy showed no intrauterine abnormality, 29 women (60%) had recurrence of complaints and 12 (24%) a re-intervention.

Conclusion

In premenopausal women with abnormal uterine bleeding, treatment of intrauterine pathology often does not reduce the complaints, thus questioning the effectiveness of hysteroscopic removal of these structures.
Literatur
1.
Zurück zum Zitat Spencer CP, Whitehead MI (1999) Endometrial assessment re-visited. Br J Obstet Gynaecol 106(7):623–632CrossRef Spencer CP, Whitehead MI (1999) Endometrial assessment re-visited. Br J Obstet Gynaecol 106(7):623–632CrossRef
2.
Zurück zum Zitat Fraser IS, Critchley HO, Munro MG, Broder M (2007) Writing Group for this menstrual agreement. A process designed to lead to international agreement on terminologies and definitions used to describe abnormalities of menstrual bleeding. Fertil Steril 87(3):466–476CrossRef Fraser IS, Critchley HO, Munro MG, Broder M (2007) Writing Group for this menstrual agreement. A process designed to lead to international agreement on terminologies and definitions used to describe abnormalities of menstrual bleeding. Fertil Steril 87(3):466–476CrossRef
3.
Zurück zum Zitat Munro MG, Critchley HO, Broder MS, Fraser IS (2011) Disorders FWGoM. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. Int J Gynaecol Obstet 113(1):3–13CrossRef Munro MG, Critchley HO, Broder MS, Fraser IS (2011) Disorders FWGoM. FIGO classification system (PALM-COEIN) for causes of abnormal uterine bleeding in nongravid women of reproductive age. Int J Gynaecol Obstet 113(1):3–13CrossRef
4.
Zurück zum Zitat Preutthipan S, Herabutya Y (2005) Hysteroscopic polypectomy in 240 premenopausal and postmenopausal women. Fertil Steril 83(3):705–709CrossRef Preutthipan S, Herabutya Y (2005) Hysteroscopic polypectomy in 240 premenopausal and postmenopausal women. Fertil Steril 83(3):705–709CrossRef
5.
Zurück zum Zitat Gimpelson RJ, Rappold HO (1988) A comparative study between panoramic hysteroscopy with directed biopsies and dilatation and curettage. A review of 276 cases. Am J Obstet Gynecol 158(3 Pt 1):489–492CrossRef Gimpelson RJ, Rappold HO (1988) A comparative study between panoramic hysteroscopy with directed biopsies and dilatation and curettage. A review of 276 cases. Am J Obstet Gynecol 158(3 Pt 1):489–492CrossRef
6.
Zurück zum Zitat Campo R, Van Belle Y, Rombauts L, Brosens I, Gordts S (1999) Office mini-hysteroscopy. Hum Reprod Update 5(1):73–81CrossRef Campo R, Van Belle Y, Rombauts L, Brosens I, Gordts S (1999) Office mini-hysteroscopy. Hum Reprod Update 5(1):73–81CrossRef
7.
Zurück zum Zitat Litta P, Cosmi E, Saccardi C, Esposito C, Rui R, Ambrosini G (2008) Outpatient operative polypectomy using a 5 mm-hysteroscope without anaesthesia and/or analgesia: advantages and limits. Eur J Obstet Gynecol Reprod Biol 139(2):210–214CrossRef Litta P, Cosmi E, Saccardi C, Esposito C, Rui R, Ambrosini G (2008) Outpatient operative polypectomy using a 5 mm-hysteroscope without anaesthesia and/or analgesia: advantages and limits. Eur J Obstet Gynecol Reprod Biol 139(2):210–214CrossRef
8.
Zurück zum Zitat Hamani Y, Eldar I, Sela HY, Voss E, Haimov-Kochman R (2013) The clinical significance of small endometrial polyps. Eur J Obstet Gynecol Reprod Biol 170(2):497–500CrossRef Hamani Y, Eldar I, Sela HY, Voss E, Haimov-Kochman R (2013) The clinical significance of small endometrial polyps. Eur J Obstet Gynecol Reprod Biol 170(2):497–500CrossRef
9.
Zurück zum Zitat van Dongen H, Janssen CA, Smeets MJ, Emanuel MH, Jansen FW (2009) The clinical relevance of hysteroscopic polypectomy in premenopausal women with abnormal uterine bleeding. Br J Obstet Gynaecol 116(10):1387–1390CrossRef van Dongen H, Janssen CA, Smeets MJ, Emanuel MH, Jansen FW (2009) The clinical relevance of hysteroscopic polypectomy in premenopausal women with abnormal uterine bleeding. Br J Obstet Gynaecol 116(10):1387–1390CrossRef
10.
Zurück zum Zitat Henriquez DD, van Dongen H, Wolterbeek R, Jansen FW (2007) Polypectomy in premenopausal women with abnormal uterine bleeding: effectiveness of hysteroscopic removal. J Minim Invasive Gynecol 14(1):59–63CrossRef Henriquez DD, van Dongen H, Wolterbeek R, Jansen FW (2007) Polypectomy in premenopausal women with abnormal uterine bleeding: effectiveness of hysteroscopic removal. J Minim Invasive Gynecol 14(1):59–63CrossRef
11.
Zurück zum Zitat van Buuren S (2012) Flexible imputation of missing data. Taylor & Francis, LondnCrossRef van Buuren S (2012) Flexible imputation of missing data. Taylor & Francis, LondnCrossRef
12.
Zurück zum Zitat Steyerberg E (2008) Clinical prediction models: a practical approach to development, validation, and updating. Springer, New York Steyerberg E (2008) Clinical prediction models: a practical approach to development, validation, and updating. Springer, New York
13.
Zurück zum Zitat Stamatellos I, Koutsougeras G, Karamanidis D, Stamatopoulos P, Timpanidis I, Bontis J (2007) Results after hysteroscopic management of premenopausal patients with dysfunctional uterine bleeding or intrauterine lesions. Clin Exp Obstet Gynecol 34(1):35–38PubMed Stamatellos I, Koutsougeras G, Karamanidis D, Stamatopoulos P, Timpanidis I, Bontis J (2007) Results after hysteroscopic management of premenopausal patients with dysfunctional uterine bleeding or intrauterine lesions. Clin Exp Obstet Gynecol 34(1):35–38PubMed
Metadaten
Titel
Recurrence and prediction of abnormal uterine bleeding and re-intervention after initial hysteroscopic treatment: a retrospective cohort study
verfasst von
Silke F. G. Schaffrath
Janique R. J. Dreessen
Marlies Y. Bongers
Sander M. J. van Kuijk
Ben W. J. Mol
Josje Langenveld
Publikationsdatum
15.11.2019
Verlag
Springer Berlin Heidelberg
Erschienen in
Archives of Gynecology and Obstetrics / Ausgabe 6/2019
Print ISSN: 0932-0067
Elektronische ISSN: 1432-0711
DOI
https://doi.org/10.1007/s00404-019-05380-w

Weitere Artikel der Ausgabe 6/2019

Archives of Gynecology and Obstetrics 6/2019 Zur Ausgabe

Update Gynäkologie

Bestellen Sie unseren Fach-Newsletter und bleiben Sie gut informiert – ganz bequem per eMail.