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01.12.2011 | Case report | Ausgabe 1/2011 Open Access

Journal of Medical Case Reports 1/2011

Recurrent tibial intra-cortical osteosarcoma: a case report and review of the literature

Journal of Medical Case Reports > Ausgabe 1/2011
Olarn Arpornchayanon, Taninnit Leerapun, Chate Sivasomboon, Jongkolnee Settakorn, Nantawit Sugandhavesa, Dumnoensun Pruksakorn
Wichtige Hinweise

Electronic supplementary material

The online version of this article (doi:10.​1186/​1752-1947-5-93) contains supplementary material, which is available to authorized users.

Competing interests

The authors declare that they have no competing interests.

Authors' contributions

DP wrote the draft manuscript. OA, TL, NS and DP carried out the operation and the patient follow-up. CS participated in the radiological evaluation. JS participated in the pathological studies. All authors read and approved the final manuscript.



Intra-cortical osteosarcoma is the rarest subtype of osseous-producing tumor. Most reported cases present a low-grade histology with slow progression and good oncological control after adequate treatment. In this report, we describe a case and review the literature to propose adequate treatment.

Case presentation

We present the case of a 21-year-old Thai woman who was thought to have an intra-cortical osteosarcoma of the right tibia. We performed a wide resection and reconstruction with bone transportation using an Ilizarov external fixator. The tumor recurred five years later at the same site with a similar histology. We performed a new resection and reconstruction by ankle arthrodesis with adjuvant chemotherapy. At the last follow-up, she had remained active and free from disease for seven years.


This case report of recurrent intra-cortical osteosarcoma describes an atypical presentation. The low-grade histology, adequate surgical margin and adjuvant chemotherapy of the recurrent lesion were favorable factors, and our patient has remained free of any tumor recurrence.

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