11.01.2025 | Research
Reduced-dose CT scan of colorectal cancer
verfasst von:
Shenglin Li, Xinmei Yang, Yuntai Cao, Long Yuan, Ting Lu, Yuxuan Wang, Jun Zhao, Wenjuan Zhang, Junlin Zhou, Guojin Zhang
Erschienen in:
Abdominal Radiology
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Excerpt
Colorectal cancer (CRC) is the third most common malignancy and second leading cause of cancer-related deaths worldwide [
1]. With the clinical application of neoadjuvant chemo-radiotherapy, targeted therapy, and immunotherapy, the long-term survival outcome of CRC patients has greatly improved [
2,
3]. However, the five-year overall survival rate of patients with advanced colorectal cancer remains less than 61% [
4]. Therefore, the American Cancer Society recommends starting screening at 45 years of age to help reduce the incidence and mortality of CRC [
5]. These screening protocols mainly consist of stool and blood-based laboratory tests paired with visual examinations and imaging. Computed tomography (CT) has been shown to be the more tolerable imaging technique, with fewer complications and greater scope of application, and can assess obstructed or challenging anatomy compared to optical colonoscopy [
6‐
8]. …